Orbital lymphangioma: an analysis of 26 patients

Abstract

Aim-To evaluate retrospective data on the clinical findings, histological features, radiological diagnosis, and management outcomes in orbital lymphangioma. Methods-Data on 26 orbital lymphangioma patients managed over 16 years were re-evaluated. The computed tomograph and magnetic resonance scans and histological slides were reviewed. Parametric techniques were used to assess correlations among clinical, radiological, and histopathological factors. Results-At presentation proptosis was present in 85%, ptosis in 73%, and restrictive eye movements in 46% of patients. The accuracy of the initial radiology interpretations was 77%. 24 cases required one or more surgeries. The mean follow up was 9.2 years (range 1-14 years). 58% of patients developed recurrences. In cases that recurred, motility restriction was significantly more frequent at initial examination than cases without recurrence (p<0.05). After therapy, 75% of patients were satisfied with their visual function and cosmetic appearance. Conclusions-Conservative management of orbital lymphangioma with multiple partial resections may achieve satisfactory results. (Br J Ophthalmol 1999;83:76-80)

Pediatric Orbit Tumors and Tumorlike Lesions: Nonosseous Lesions of the Extraocular Orbit

“…Venouslymphatic malformations grow with the patient, but accelerated growth may occur in response to hormonal changes such as those associated with puberty or pregnancy (26,31). Restricted ocular motility is another relatively frequent complaint, occurring in up to one-half of patients (37). Visual disturbance is uncommon at the time of presentation, even with relatively large lesions, but may develop after repeated episodes of hemorrhage in deep lesions (18,31).…”

“…(Fig 13). The lesion can have components with cysts more than 1-2 cm in size (macrocystic) and portions that appear more solid (microcystic) (32,37).…”

Sclerotherapy for Orbital Lymphangioma – Case Series and Literature Review

“…Intraorbital haemorrhage has been reported as a common cause of exacerbation of proptosis. Such haemorrhage was spontaneous, or after local/systemic infection, or local trauma (2,5,6). …”

Linfangioma orbitário: relato de caso

“…Trata-se de paciente do sexo feminino, que é discretamente mais acometido por linfangioma que o masculino, na proporção de 1,4:1 (2,5) . A idade de aparecimento dos sintomas também coincidiu com a relatada na literatura, que é na primeira década de vida, embora o tumor possa manifestar-se desde o nascimento até a idade adulta (2) .…”

“…O linfangioma pode acometer apenas a conjuntiva e a pálpebra, localizar-se na órbita ou apresentar-se com os dois componentes, superficial e profundo (2) . Pode manifestar-se clinicamente por proptose, restrição da motilidade ocular extrínseca, ptose (4)(5)(6)(7) , dor, diplopia (4,8) , exposição corneana (4) , perda visual por neuropatia óptica compressiva e ambliopia (7) . Exacerbações do quadro clínico tendem a ocorrer em casos de hemorragia intralesional e episódios de infecção das vias aéreas superiores, que resultam em hiperplasia linfóide por reação do sistema imunológico, o que explicaria a reativação do quadro (2,9) .…”