Orbital apex syndrome secondary to herpes zoster ophthalmicus

Ruiz-Arranz, Celia; Reche-Sainz, J.A.; Uña-Iglesias, M.C. de; Ortueta‐Olartecoechea, Ana; Muñoz-Gallego, A.; Ferro-Osuna, M.

doi:10.1016/j.oftale.2020.06.009

Cited by 3 publications

(29 citation statements)

References 10 publications

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“…About 50-85% of HZO cases experience ocular complaints such as conjunctivitis, uveitis, episcleritis, keratitis, or retinitis [20,21]. Rare manifestations are the sterile iris abscess [22], oculomotoric nerve palsy [23], superior orbital fissure syndrome [24], orbital apex syndrome [25], and isolated nonreactive mydriasis [26].…”

Section: Hz Ophthalmicus (Hzo)mentioning

confidence: 99%

Herpes zoster: A Review of Clinical Manifestations and Management

Patil

Goldust

Wollina

2022

Viruses

183

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The Varicella-zoster virus (VZV) or human herpes virus 3 is a neurotropic human alpha herpes virus responsible for chickenpox/varicella and shingles/herpes zoster (HZ). This review will focus on HZ. Since HZ is secondary to varicella, its incidence increases with age. In children and youngsters, HZ is rare and associated to metabolic and neoplastic disorders. In adults, advanced age, distress, other infections (such as AIDS or COVID-19), and immunosuppression are the most common risk factors. HZ reactivation has recently been observed after COVID-19 vaccination. The disease shows different clinical stages of variable clinical manifestations. Some of the manifestations bear a higher risk of complications. Among the possible complications, postherpetic neuralgia, a chronic pain disease, is one of the most frequent. HZ vasculitis is associated with morbidity and mortality. Renal and gastrointestinal complications have been reported. The cornerstone of treatment is early intervention with acyclovir or brivudine. Second-line treatments are available. Pain management is essential. For (secondary) prophylaxis, currently two HZV vaccines are available for healthy older adults, a live attenuated VZV vaccine and a recombinant adjuvanted VZV glycoprotein E subunit vaccine. The latter allows vaccination also in severely immunosuppressed patients. This review focuses on manifestations of HZ and its management. Although several articles have been published on HZ, the literature continues to evolve, especially in regard to patients with comorbidities and immunocompromised patients. VZV reactivation has also emerged as an important point of discussion during the COVID-19 pandemic, especially after vaccination. The objective of this review is to discuss current updates related to clinical presentations, complications, and management of HZ.

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Section: Hz Ophthalmicus (Hzo)mentioning

confidence: 99%

Herpes zoster: A Review of Clinical Manifestations and Management

Patil

Goldust

Wollina

2022

Viruses

183

123

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“…The authors reviewed previous case reports describing OAS, which totaled 19 cases. 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Among the published cases of OAS, the average age of patients was approximately 67 (range 29–84) years. 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Most affected patients were women (80%).…”

Section: Discussionmentioning

confidence: 99%

“… 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Most affected patients were women (80%). 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 Our patient was male with an older age than previous reports. Some comorbidities were reported, including diabetes mellitus, hypertension, acquired immunodeficiency syndrome, multiple myeloma, and leukemia.…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, several cases OAS caused by herpes zoster infection have been more reported. 9 , 10 , 11 , 12 , 13 , 14 Regarding OAS, various clinical presentations, treatments, and long‐term sequelae can occur. Current evidence published in the literature suggests that OAS treatment is possible using antiviral plus anti‐inflammatory drugs via either an oral or intravenous route.…”

Section: Introductionmentioning

confidence: 99%

“…However, a definitive treatment of this condition remains unclear. 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 …”

Section: Introductionmentioning

confidence: 99%

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Orbital apex syndrome due to herpes zoster infection in a patient with chronic kidney disease: A case report

Srimanan

Panyakorn

2023

Clinical Case Reports

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El herpes: una enfermedad viral recurrente y sus implicaciones en la salud

Ponce-Pincay,

Jaramillo-Coveña,

Landa-Rivera

2023

MQRInvestigar

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La presente investigación tuvo como objetivo comprender la naturaleza del herpes, y evaluar sus implicaciones en la salud. Metodología: fue de diseño documental y el tipo de estudio es descriptivo. Los resultados revelaron que el herpes es una enfermedad viral altamente contagiosa causada principalmente por el virus del herpes simple (HSV) y el virus varicela-zóster (VZV), que puede manifestarse en diversas formas, incluyendo herpes labial, herpes genital y herpes zóster. Además, se encontró que el herpes puede tener implicaciones graves en la salud, como complicaciones neurológicas, dolor crónico, y riesgo aumentado de adquirir otras infecciones de transmisión sexual. Las conclusiones destacaron la importancia de la detección temprana y el tratamiento adecuado del herpes para prevenir complicaciones a largo plazo y mejorar la calidad de vida de los pacientes. Además, se subrayó la necesidad de promover la educación sobre la prevención y el manejo del herpes, así como la importancia de las medidas de higiene y vacunación. El impacto de esta investigación radica en su contribución al conocimiento de una enfermedad viral prevalente que afecta a millones de personas en todo el mundo, lo que puede guiar estrategias de salud pública más efectivas y mejorar la atención médica de los pacientes afectados por el herpes, reduciendo así su carga en la salud global y mejorando la calidad de vida de las personas afectadas.

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Orbital apex syndrome secondary to herpes zoster ophthalmicus

Cited by 3 publications

References 10 publications

Herpes zoster: A Review of Clinical Manifestations and Management

Herpes zoster: A Review of Clinical Manifestations and Management

Orbital apex syndrome due to herpes zoster infection in a patient with chronic kidney disease: A case report

El herpes: una enfermedad viral recurrente y sus implicaciones en la salud

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