Oral Ulcers During the Course of Cytomegalovirus Infection in Renal Transplant Recipients

López‐Pintor, Rosa María; Hernández, Gonzalo; Arriba, Lorenzo de; Morales, José; Jiménez, Carlos; Andrés, Amado

doi:10.1016/j.transproceed.2009.06.053

Cited by 36 publications

(24 citation statements)

References 9 publications

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“…6,9,[10][11][12][13][14][15][16][17][18] However, oral manifestations of CMV infection are considered rare. 19 Although oral lesions resulting from CMV infection have been documented in several immunosuppressive conditions, oral involvement CMV has increased since the beginning of the AIDS epidemic. The diagnosis of CMV infection is made from a combination of clinical findings, as well as by laboratory tests.…”

Section: Introductionmentioning

confidence: 99%

Oral Ulcers Induced by Cytomegalovirus Infection: Report on Two Cases

Ribas¹,

Lima²

2017

J Dent Indones

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Human cytomegalovirus (CMV) is a virus that can compromise the lungs and the liver and cause infection in the gastrointestinal tract. In addition, this virus can cause infectious mononucleosis syndrome, infection in the CNS, and retinitis. Moreover, it has been associated with the development of oral hairy leukoplakia and ulcers. Objective: To report two cases of patients with HIV with oral manifestations associated with CMV infection. Case Report: In the first case, the patient sought medical attention, with complaints of weakness, fever, cough, and weight loss. In the second case, the patient complained of weakness and blurred vision for about a week. Both patients were infected with HIV and made irregular use of antiretroviral therapy. Several ulcers were observed in the mouth that caused much discomfort. The diagnosis of CMV infection was defined by the following tests: enzyme immunoassay fluorescence-CMV IgG and PCR for CMV in real time. Ganciclovir has been used in the treatment of patients, and oral ulcerations received symptomatic treatment. Conclusion: The dentist must be aware that CMV may also be responsible for the development of ulcers in the oral cavity, especially in immunocompromised patients.

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Section: Introductionmentioning

confidence: 99%

Oral Ulcers Induced by Cytomegalovirus Infection: Report on Two Cases

Ribas¹,

Lima²

2017

J Dent Indones

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“…Among the most important systemic complications are cardiovascular diseases, and electrolyte imbalance [4], as well as suppression of immune response and humoral [5], cytomegalovirus infection [6] and exacerbation of inflammatory response [7]. The most frequent oral alterations are mouth dryness [8], decreased bone trabeculation [8], malocclusion and enamel hypoplasia [9], periodontal disease [10] and other less common complications [9].…”

Section: Introductionmentioning

confidence: 99%

Oral manifestations in chronic kidney failure patients

Reis

Brancher

Deliberador

et al. 2016

Rev. Odonto Ciênc. (Online)

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Objective: Chronic kidney failure (CKF) is a progressive deterioration of the kidneys. The goal of this study was to analyze the oral manifestation of CKF in a sample of hemodialysis and transplanted patients. Methods: Eighty-three records of patients treated in the Pro-Renal Foundation in Curitiba, Brazil were used. The records were separated in four groups: Transplanted Men (TM = 14), Transplanted Women (TW = 18), Men in Hemodialysis (MHD = 28) and Women in Hemodialysis (WHD = 23). Information about oral and systemic health condition were collected. Data from each group were submitted to correspondence analysis and quantitative variables were compared by Kruskal-Wallis and Dunn's test. Significance level was 0.05. Results: Gingival inflammation, loss of periodontal support tissue, dental calculus and increase in periodontal probing depth were common findings in all patients, but significant association was found in following groups: TM presented dental calculus; TW presented a high prevalence of cardiovascular problems and saburral tongue; MHD presented poor oral hygiene, gingivitis associated with smoking; WHD presented a high prevalence of temporomandibular dysfunction. Conclusions: The most prevalent findings were increase in the periodontal probing depth and gingival recession. Unexpectedly, WHD group presented a high prevalence of temporomandibular dysfunction.Key words: Hemodialysis; Chronic kidney failure; Oral health Manifestações bucais em pacientes portadores de doença hepática crônica ResuMO Objetivo: Insuficiência Renal Crônica (IRC) é caracterizada pela perda progressiva dos rins. O objetivo deste estudo foi analisar as manifestações bucais de uma amostra de pacientes renais transplantados ou que faz hemodiálise. Metodologia: Oitenta e três prontuários de pacientes em atendimento na Fundação Pró-Renal em Curitiba, Brasil foram analisados e quarto grupos foram formados: Homens Transplantados (HT=14), Mulheres Transplantadas (MT=18), Homens em Hemodiálise (HH=28) e Mulheres em Hemodiálise (MH=23). Informações sobre a saúde bucal e sáude geral foram coletadas. Dados de cada grupo foram submetidos à análise pelo teste Kruskal-Wallis, seguido pelo teste de Dunn com nível de significância de 0,05. Resultados: Inflamação gingival, perda de tecido periodontal de suporte, cálculo dentário e aumento de profundidade de sondagem foram encontrados em todos os pacientes, mas associações significantes foram encontradas nos seguintes grupos: HT apresentaram alta prevalência de cálculo dentário; problemas cardiovasculares e língua saburosa foi observada em MT; HH são fumantes, apresentam probre higiene bucal e gengivite; em mulheres em hemodiálise foi relatada uma alta prevalência de disfunção temporomandibular. Conclusão: Em geral, os achados mais comuns são aumento de profundidade de sondagem e recessão gingival. Mulheres que realizam sessões de hemodiálise apresentam disfunção tempormandibular.

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“…Finally, oral lesions attributable to HHV-5, or cytomegalovirus (CMV), have been documented in patients with various immunosuppressive conditions, such as acquired immunodeficiency syndrome (AIDS), lymphoproliferative disorders requiring a bone marrow transplantation, and iatrogenic immunosuppression after organ transplantation. [10][11][12][13][14][15][16][17] In these cases, CMV-related oral lesions commonly appear as chronic mucosal ulcerations and will occasionally demonstrate histopathologic evidence of coinfection by HSV. [17][18][19][20][21][22] As mentioned earlier, simultaneous infection by 2 different herpesviruses has been documented.…”

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confidence: 99%