Oral Treatment of Acne vulgaris and Oil Acne with Tetracycline

Abstract

In 51 patients with acne vulgaris and 34 patients suffering from occupational oil acne the clinical effect of orally administered tetracycline was evaluated before, during and after a 3-monthly treatment (total dose of antibiotic: 1st month, 28.5 g; 2nd and 3rd months, 15.0 g). Patients treated with placebo were used as controls. Investigations of the skin fluorescence under Wood’s light were performed during the treatment period. In one half of the patients with acne vulgaris and oil acne oral treatment with tetracycline had a very good clinical effect. The purpose of this investigation was the comparison of the results of the treatment of acne vulgaris and occupational oil acne with tetracycline.

Wood’s light in dermatology

“…Wood's lamp examination of the skin normally yields a negative finding. 34,37 To monitor the effectiveness of topical applications Protective creams are useful for factory workers when gloves cannot be used. Recently, Wigger-Alberti et al 38 reported the usefulness of Wood's light examination to monitor how workers apply protective creams to their hands.…”

Elaioconiose: relato de caso

“…Treatment with systemic antibiotics, such as tetracycline, and topical and systemic retinoids has been reported, with moderate success. 5,6 Preventive measures are also recommended such the application of silicone creams, frequent hand/clothes washing and using personal protective equipment. 7 Elaioconiosis is an occupational dermatosis that needs to be identified and treated as such by a dermatologist.…”

Occupational Acne

“…Previous studies reported favorable effects of systemic tetracycline for 3 months in the treatment of oil acne [51]. Isotretinoin is also known to play a role in the treatment of oil acne [52].…”