Oral syringes with millilitre measurements are safer than dosing cups for administration of medication for children

Moore, Yasmin; Iqbal, Amar

doi:10.1136/archdischild-2016-312289

Cited by 3 publications

(3 citation statements)

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“…Of the three devices studied, the oral syringe has the lowest measurement error despite being significantly higher than the reference value, followed by the transparent dosing spoon and finally the double-dosing spoon. Previous studies also reported the oral syringe is the most accurate device [10,22].…”

Section: Discussionmentioning

confidence: 91%

Dosing Accuracy of Oral Extemporaneous Suspensions of Antibiotics: Measuring Procedures and Administration Devices

Neves

Auxtero

2021

Pharmaceutics

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Extemporaneous suspensions are often marketed with several administration devices that can be freely used by patients/caregivers. The homogeneity of suspensions requires shaking before use. Hence, it is crucial to assess the precision of all devices and the users’ awareness of the shaking procedure. This study was conducted at University Institute Egas Moniz with 40 pharmacy students who were asked to measure 2.5 and 5 mL of two extemporaneous azithromycin suspensions. Formulation A is marketed with a double-dosing spoon and oral syringe, whereas B includes a transparent dosing spoon. Both have a reconstitution cup. The user’s preference for administration devices, the degree of compliance with the ‘shake before use’ instruction and the accuracy of the manipulation were assessed. The double-dosing spoon was the preferred device. The “shake before use” instruction was overlooked by most volunteers. The average measured volumes obtained with the double-dosing spoon were significantly different from the ones obtained with the oral syringe (p < 0.001) and significantly lower than the reference dose (p < 0.001). The oral syringe originates significantly higher values than the reference dose (p < 0.001). The dosing spoons values were significantly different from each other (p < 0.001). Liquid medicines containing several administration devices may be a challenge since they are nonequivalent.

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Section: Discussionmentioning

confidence: 91%

Dosing Accuracy of Oral Extemporaneous Suspensions of Antibiotics: Measuring Procedures and Administration Devices

Neves

Auxtero

2021

Pharmaceutics

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“…The fluid injector (oral syringe) was the principal device used in the pediatric wards, possibly reflecting the high frequency of tubal feeding through the nose, mouth, or gastrostomy in hospitalized pediatric patients. Use of the fluid injector was also common because of the ease of delivering a dissolved or suspended medication into the child’s mouth 12 and the ready availability of the device in hospitals (the oral syringe is usually not provided with prescribed medications at community pharmacies in Japan).…”

Section: Discussionmentioning

confidence: 99%

“…9,10 The use of appropriate measuring devices with oral medications is encouraged, particularly the use of oral syringes as they are more accurate than graduated pipettes or measuring spoons. 11,12 However, which devices caregivers prefer to use in a pediatric ward and at home is not well known.…”

Section: Introductionmentioning

confidence: 99%

Age-Appropriate Pediatric Dosage Forms in Japan: Insights into End-User Perceptions From an Observational Cross-Sectional Survey Assessing the Acceptability of Oral Formulation

Saito

Akabane

Komura

et al. 2019

Ther Innov Regul Sci

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Issues on Powder Forms for Oral Solution and Suspension for Pediatric Patients in Japan: A Questionnaire-Based Observational Survey to Pediatric Pharmacists

Saito

Nakamura

Yamatani

2022

Ther Innov Regul Sci

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Oral syringes with millilitre measurements are safer than dosing cups for administration of medication for children

Cited by 3 publications

References 0 publications

Dosing Accuracy of Oral Extemporaneous Suspensions of Antibiotics: Measuring Procedures and Administration Devices

Dosing Accuracy of Oral Extemporaneous Suspensions of Antibiotics: Measuring Procedures and Administration Devices

Age-Appropriate Pediatric Dosage Forms in Japan: Insights into End-User Perceptions From an Observational Cross-Sectional Survey Assessing the Acceptability of Oral Formulation

Issues on Powder Forms for Oral Solution and Suspension for Pediatric Patients in Japan: A Questionnaire-Based Observational Survey to Pediatric Pharmacists

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