Oral Submucous Fibrosis: Case Report and Review of Diagnosis and Treatment

Aziz, Shahid R.

doi:10.1016/j.joms.2008.06.064

Cited by 55 publications

(47 citation statements)

References 8 publications

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“…11,12,13,14,15,16 The definition by the World Health Organization(WHO) of an precancerous oral condition: -a generalized pathological state of the oral mucosa associated with a significantly increased risk of cancer‖ fits well with the characteristics of OSMF. 17,18 The condition is thought to be multifactorial in origin with a high incidence in people who chew areca-nut,and a significant malignant transformation rate (7-30%) 19 poses global problems for public health. The physical effects, which include a burning sensation in the mucosa and progressive trismus, can also have psychological and social implications for patients.…”

Section: IIImentioning

confidence: 99%

“…Excessive salivation, defective gustatory sensation, and dryness of the mouth can also occur in clinically early stages of the disease 4 . Later symptoms After varying periods of time, in some cases a few years after the appearance of the initial symptoms, patients complain of stiffening of certain areas of the oral mucosa, leading to (I) difficulties in opening the mouth, (2) in ability to whistle or to blow out a candle, and (3) difficulties in swallowing 19 . When the fibrosis reaches the pharynx, the patient may experience referred pain in the ears 20 .…”

Section: Early Symptomsmentioning

confidence: 99%

“…As said before OSMF has a malignant transformation rate of 7-30%. 19 Pathogenesis is thought to be multifactorial. The carcinogenic effects of tobacco acting in synergy with areca-nut is well known, but the second report on betel quid by the International Agency for Research on Cancer (IARC)identified areca-nut as a -group one carcinogen‖ 34,35,36 .…”

Section: Early Symptomsmentioning

confidence: 99%

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Oral Submucous Fibrosis Turning Malignant. A case report and review of literature.

Jesudasan¹

2013

IOSR-JDMS

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Section: IIImentioning

confidence: 99%

Section: Early Symptomsmentioning

confidence: 99%

Section: Early Symptomsmentioning

confidence: 99%

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Oral Submucous Fibrosis Turning Malignant. A case report and review of literature.

Jesudasan¹

2013

IOSR-JDMS

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“…This precancerous condition is caused by betelnut chewing and is mainly endemic to the Asian subcontinent. 1,2 Arecanut is identified as group one carcinogen by International Agency for research on cancer (IARC). [3][4][5] OSMF has a high malignant transformation rate of 7-30%.…”

Section: Introductionmentioning

confidence: 99%

“…[3][4][5] OSMF has a high malignant transformation rate of 7-30%. [1][2][3][4][5] A variety of treatment modalities are suggested. [4][5][6] The characteristic features of OSMF are loss of pigmentation, blanching and leathery texture of oral mucosa, depapillation and reduced movement of tongue, progressive reduction of mouth opening and sunken cheeks.…”

Section: Introductionmentioning

confidence: 99%

Clinical evaluation of different treatment methods for OSMF: A five-year experience with 144 cases

Bhatnagar¹

2020

JOOO

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Introduction: Oral submucous fibrosis (OSMF) is chronic, insidious, debilitating condition of oral cavity and sometimes pharynx, characterized by progressive hyalinization of juxtaepithelial tissue and progressive fibrosis of the oral cavity. It is a premalignant disease. The repeated ulceration in mouth and the progressive reduction of mouth opening is very debilitating to the patient. The disease once occurs does not reverse. None of the modalities provide the complete remission of the disease and are aimed at improving the functions of the mouth like chewing and opening of mouth. Aims and Objectives: The aim of this study is to establish a treatment protocol for OSMF depending on the stage of the disease. As the disease has multiple stages, a single treatment modality is not adequate for the treatment. The treatment has to be devised according to the symptoms of the patient and the stage of the disease. Materials and Methods: It is a retrospective study done on 144 patients who are followed up for six months. The treatment was done depending on the stage of disease and the outcomes were evaluated. Results: The cessation of the arecanut chewing habits and regular physiotherapy is a single most important factor for the success of treatment. Noninvasive treatment methods give good results with patient in stage I and Stage II disease. In our institute, single stage pedicled nasolabial flap worked well for the patients in stage III and Stage IV disease. The good mouth opening was achieved even in patients with mouth opening less than 5mm. Conclusion:The proposed protocol is very effective in treating patients with OSMF. The medicinal treatment is effective in patients with mouth opening more than 20 mm. It helps in the resolution of symptoms and improvement of mouth opening. However, in severe cases with mouth opening less then 20mm, surgical treatment is required. Among the surgical treatments used by us single stage pedicled nasolabial flap gave the best results.

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Interventions for managing oral submucous fibrosis

Jones,

Veale,

et al. 2024

Cochrane Database of Systematic Reviews

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Oral Submucous Fibrosis: Case Report and Review of Diagnosis and Treatment

Cited by 55 publications

References 8 publications

Oral Submucous Fibrosis Turning Malignant. A case report and review of literature.

Oral Submucous Fibrosis Turning Malignant. A case report and review of literature.

Clinical evaluation of different treatment methods for OSMF: A five-year experience with 144 cases

Interventions for managing oral submucous fibrosis

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