Oral sex practices, oral human papillomavirus and correlations between oral and cervical human papillomavirus prevalence among female sex workers in Lima, Peru

Brown, Brandon; Blas, Magaly M.; Cabral, Alejandra; Cárcamo, César; Gravitt, Patti E.; Halsey, Neal A.

doi:10.1258/ijsa.2011.010541

Cited by 23 publications

(29 citation statements)

References 25 publications

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“…The present study aimed at assessing the prevalence of HPV infection at cervical, oropharyngeal and anal sites of sex workers as well as exploring association between sexual behaviour, condom usage and HPV positivity as well as investigating awareness of the prevention of HPV and other STDs of this HR population. This study's results were consistent with previous papers reporting a significantly higher prevalence of HPV infection among FSWs than that of the general population (Kjaer et al 2000;Ford et al 2003;Canadas et al 2004;Mak et al 2004;del Amo et al 2005;Ortiz et al 2006;Sultana et al 2008;Brown et al 2011;Shikova et al 2011) as the HPV DNA was detected in at least one location in a great majority (82.4%) of the FSWs and less than half of the control women (46.2%).…”

Section: Discussionsupporting

confidence: 92%

“…; Brown et al . ; Shikova et al . ) as the HPV DNA was detected in at least one location in a great majority (82.4%) of the FSWs and less than half of the control women (46.2%).…”

Section: Discussionmentioning

confidence: 99%

“…Some studies have examined the prevalence of HPV infection among female sex workers (FSWs), a population at higher risk of infection because of their sexual behaviour (Kjaer et al 2000;Ford et al 2003;Tideman et al 2003;Canadas et al 2004;Mak et al 2004;del Amo et al 2005;Ortiz et al 2006;Sultana et al 2008;Brown et al 2011;Shikova et al 2011). A majority of the papers demonstrate a significantly higher HPV prevalence in cervical swabs of sex workers than that of the general population (Kjaer et al 2000;Ford et al 2003;Mak et al 2004;del Amo et al 2005;Ortiz et al 2006;Sultana et al 2008).…”

Section: Introductionmentioning

confidence: 99%

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Human papillomavirus infections among Hungarian female sex workers

Marek

Dergez

D’Cruz

et al. 2013

Eur J Cancer Care (Engl)

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The purpose of this study was to assess the human papillomavirus (HPV) prevalence in cervical, oropharyngeal and anal samples of the high-risk population of Hungarian female sex workers (FSWs). HPV testing of swab specimens from FSWs (n = 34) using polymerase chain reaction (PCR) methodology was performed. Results were compared with control group (n = 52) matched for age. Questionnaires were used to obtain data regarding participants' sexual behaviour. Data were analysed using SPSS. HPV DNA was detected in at least one location in a great majority of FSWs (82.4%), compared with 46.2% of the general female population (P < 0.05). Both the cervical and the anal samples of sex workers showed higher infection rates than those of controls (64.7% vs. 34.6% and 50.0% vs. 15.4%, respectively, P < 0.05). High-risk HPV prevalence was also significantly higher in sex workers (55.9% vs. 25.0%, P < 0.05). A significantly higher proportion of FSWs had a history of genital warts (26.5% vs. 3.8%, P < 0.05). The results suggest that condom use may not result in adequate protection from HPV infection. The high infection rates among FSWs should be viewed as a priority group for HPV and cervical cancer prevention programmes since they are sources of HPV infection for the general population.

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Section: Discussionsupporting

confidence: 92%

“…; Brown et al . ; Shikova et al . ) as the HPV DNA was detected in at least one location in a great majority (82.4%) of the FSWs and less than half of the control women (46.2%).…”

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Human papillomavirus infections among Hungarian female sex workers

Marek

Dergez

D’Cruz

et al. 2013

Eur J Cancer Care (Engl)

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“…Consistent with this hypothesis, Brown et al. reported that only 7.6% of women who practiced oral sex had oral HPV. The absence of HPV was higher in women who practiced oral sex than those who did not (33.8% vs. 20%), result similar to that shown by Giraldo et al.…”

Section: Discussionmentioning

confidence: 87%

Association between oral DNA‐HPV and genital DNA‐HPV

Vidotti

Vidal

Monteiro

et al. 2013

J Oral Pathology Medicine

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“…For example, the prevalence of oncogenic HPV in the oral cavity is significantly lower than in the cervix, even among women with similar histories of oral and vaginal sexual activity [4,5]. Furthermore, the relative risk of anogenital HIV-1 transmission is three times higher than oral HIV transmission [6].…”

Section: Introductionmentioning

confidence: 99%

Comparison of the immune microenvironment of the oral cavity and cervix in healthy women

et al. 2013

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Background Despite similar frequencies of exposure, the low prevalence of certain sexually transmitted infections such as Chlamydia, HPV and HIV-1 in the oral cavity relative to the cervix is poorly understood. This could be explained in part by differences in host immune microenvironments between these two anatomic sites. Objective We compared the concentration and correlation of 27 different immune markers in paired secretion specimens collected from the oral and cervical mucosa of healthy women. Methods Paired oral and cervical secretion specimens were collected from thirty-nine women. The concentration of twenty-seven different immune markers was estimated using a Luminex multiplex assay. Marker concentration was normalized to total protein present in the specimen. Median immune marker concentrations were compared across anatomic sites. Unsupervised hierarchical clustering analysis was utilized to identify groups of markers that shared similar patterns of relative concentrations across anatomic sites. Results The oral cavity had significantly higher concentrations of eotaxin, IFN-γ, IL-2, IL-4, IL-5, IL-7, IL-9, IL-13, IL-15, PDGF-BB, TNF-α, (p < 0.01 for each) while the cervix had higher concentrations of proinflammatory markers such as FGF-basic, IL-1ra, IL-1β, IL-6, IL-8, IP-10, G-CSF, GM-CSF, MCP-1, MIP-1β, VEGF (p < 0.01 for each). Hierarchical cluster analysis identified two groups of immune markers comprised of T-cell related immune markers with significantly higher concentrations in the oral cavity relative to the cervix, and a third cluster consisting of mostly inflammatory immune markers which were higher concentrations in the cervix. The oral cavity had a larger number of significant inter-marker correlations as compared to the cervix. Conclusions The oral cavity and cervix have significantly different immune marker profiles, which may in part explain the significantly lower burden of sexually transmitted infections such as Chlamydia, HPV, and HIV-1 in the oral cavity vs. the cervix.

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Oral sex practices, oral human papillomavirus and correlations between oral and cervical human papillomavirus prevalence among female sex workers in Lima, Peru

Cited by 23 publications

References 25 publications

Human papillomavirus infections among Hungarian female sex workers

Human papillomavirus infections among Hungarian female sex workers

Association between oral DNA‐HPV and genital DNA‐HPV

Comparison of the immune microenvironment of the oral cavity and cervix in healthy women

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