Oral Sarcoidosis: Report of a Case and Review of Literature

Kasamatsu, Atsushi; Kanazawa, Harusachi; Watanabe, Toshihide; Matsuzaki, Osamu

doi:10.1016/j.joms.2005.09.028

Cited by 41 publications

(49 citation statements)

References 14 publications

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“…Head and neck lesions of sarcoidosis are manifested in 10 to 15% of patients [2,3]. Oral involvement of sarcoidosis is relatively rare and usually the buccal mucosa, lips, gingivae, tongue and palate are the affected sites [1,4]. Oral manifestation of sarcoidosis has been described and includes multiple nodular painless indistinct ulceration of gingiva, buccal mucosa, labial mucosa and palate [5].…”

Section: Discussionmentioning

confidence: 99%

Sarcoidosis Presenting as Isolated Gingival Enlargement: A Rare Case Entity

Tripathi

Aggarwal

Chopra

et al. 2014

JCDR

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Section: Discussionmentioning

confidence: 99%

Sarcoidosis Presenting as Isolated Gingival Enlargement: A Rare Case Entity

Tripathi

Aggarwal

Chopra

et al. 2014

JCDR

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“…Oral lesions are infrequent in sarcoidosis (5,6). A recent review of the English-language literature turned up only 68 well-documented cases of oral sarcoidosis.…”

Section: Discussionmentioning

confidence: 99%

“…In very few cases do the lesions affect more than one localization (6). Clinically, the lesions usually consist of diffuse enlargement at the submucous level or a nodular lesion, firm to the touch, with normal overlying mucous membrane (5). Papulae and superficial ulcerations have also been observed (5,7).…”

Section: Discussionmentioning

confidence: 99%

Specific (granulomatous) oral lesions of sarcoidosis ; Report of two cases

Marcoval

Mañá²

2010

Med Oral

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Sarcoidosis is a multisystemic granulomatous disease of unknown etiology that usually presents with bilateral hiliar adenopathies, pulmonary infiltrations, and ocular and cutaneous lesions. The specific cutaneous lesions, or granulomatous, are produced in from 9% to 37% of patients with systemic sarcoidosis. Nevertheless, few patients have been described having specific lesions from sarcoidosis in the oral mucous membrane. We present 2 patients with systemic sarcoidosis who developed specific sarcoidosis lesions in the oral mucous membrane. The first patient presented a plaque on the tongue of a chronic nature associated with facial lupus pernio. The second patient presented a rapidly growing nodular lesion on the lower lip that was in fact the presentation sign of the disease. Although infrequent, oral lesions may constitute the first sign of systemic sarcoidosis. For this reason the oral mucous membrane needs to be explored when there is suspicion of sarcoidosis, and systemic sarcoidosis must be included in the differential diagnosis of oral granulomatous lesions.

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“…6 Involvement of the oral mucous membranes is unusual and distinctly rare: Tongue (23%), buccal mucosa and vestibule (23%), lip (23%), hard and soft palate (17%) and gingiva (14%) indicating that oral sarcoidosis affects any site of the oral mucosa excluding the floor of the mouth. 11,12 Sarcoidosis of the gingivae as the primary or initial clinical lesion must be considered highly unusual as there are relatively few reports of gingival sarcoidosis. Gingival sarcoidosis often appears as drug-induced gingivitis.…”

Section: Introductionmentioning

confidence: 99%

“…13 Oral mucosal involvement in sarcoidosis usually manifests after systemic symptoms develop. 12 Oral manifestations of sarcoidosis have been described and include multiple, nodular, painless, indistinct ulcerations of the gingiva, buccal mucosa, labial mucosae and palate. Biopsy of oral sarcoidosis lesions reveal noncaseating granulomas with associated multinucleate giant cells and a lymphocytic infiltrate.…”

Section: Introductionmentioning

confidence: 99%