2008
DOI: 10.1016/j.pnpbp.2007.09.007
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Oral risperidone, olanzapine and quetiapine versus haloperidol in psychotic agitation

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Cited by 53 publications
(27 citation statements)
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“…Sublingual asenapine (level 3),134 haloperidol IM (level 3),131, 135, 136 haloperidol IM + midazolam IM (level 3),131, 137 haloperidol IM + promethazine IM (level 3),131, 137, 138 risperidone ODT (level 3),136 and ziprasidone IM (level 3)131, 137, 139 are recommended as a second‐line treatment. Haloperidol per os (PO) (level 4),140, 141 loxapine IM (level 4) (clinical opinion), quetiapine PO (level 4),141 and risperidone PO (level 4)140 are included as third‐line options (Table 11). …”
Section: Acute Management Of Bipolar Maniamentioning
confidence: 99%
“…Sublingual asenapine (level 3),134 haloperidol IM (level 3),131, 135, 136 haloperidol IM + midazolam IM (level 3),131, 137 haloperidol IM + promethazine IM (level 3),131, 137, 138 risperidone ODT (level 3),136 and ziprasidone IM (level 3)131, 137, 139 are recommended as a second‐line treatment. Haloperidol per os (PO) (level 4),140, 141 loxapine IM (level 4) (clinical opinion), quetiapine PO (level 4),141 and risperidone PO (level 4)140 are included as third‐line options (Table 11). …”
Section: Acute Management Of Bipolar Maniamentioning
confidence: 99%
“…Based on current data, the oral atypical antipsychotic agents, risperidone (level 2) (29,30), olanzapine (level 2) (30), and quetiapine (level 3) (30,31), should be considered first in the treatment of acute agitation. In patients who refuse oral medications, intramuscular olanzapine (level 2) (32-35), ziprasidone (level 2) (35)(36)(37)(38), and aripiprazole (level 2) (39) or a combination of intramuscular haloperidol and a benzodiazepine should be considered (level 2) (29,35,38,40,41).…”
Section: Psychosocial Interventionsmentioning
confidence: 99%
“…In emergency room psychiatric settings, quetiapine at doses ranging from 300 to 800 mg/day has been shown to be as effective as olanzapine and risperidone, and better tolerated than haloperidol (Villari 2008), despite preliminary data that suggested it to be less efficacious than olanzapine and risperidone (Raja 2003). Relative to haloperidol, quetiapine at doses ranging from 150 to 750 mg has direct calming effects on agitation independent of its effect in improving psychosis.…”
Section: Quetiapinementioning
confidence: 99%