Oral propranolol in the treatment of proliferating infantile haemangiomas: British Society for Paediatric Dermatology consensus guidelines

Šolman, Lea; Glover, Mary; Beattie, P.E.; Buckley, H; Clark, S.M.; Gach, J; Giardini, Alessandro; Helbling, Ignacio Marcelo; Hewitt, Richard; Laguda, Bisola; Langan, Sinéad; Martinéz, Anna E.; Murphy, Ruth; Proudfoot, Laura E.; Ravenscroft, Jane; Shahidullah, Hossain; Shaw, Lindsay; Syed, Samira; Wells, Louise; Flohr, Carsten

doi:10.1111/bjd.16779

Cited by 63 publications

(72 citation statements)

References 34 publications

(41 reference statements)

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“…10,11 More recent consensus statements 1,12-14 vary in specific recommendations for propranolol initiation. Both Australian and British guidelines 13,14 recommend full-term healthy infants without comorbidities may undergo outpatient initiation without in-office monitoring with initial doses of 1 mg/kg/d. 13,14 Both state that a thorough medical While rare, hypoglycemia, seen primarily with intercurrent illness or decreased feeding, is a serious potentially life-threatening risk, 16 other risks include bronchospasm and wheezing, usually in the context of a respiratory illness, cold hands and feet, gastrointestinal upset, and sleep disturbances.…”

Section: Potential Risks Associated With Betablocker Treatmentmentioning

confidence: 99%

Management of infantile hemangiomas during the COVID pandemic

Frieden

Püttgen

Drolet

et al. 2020

Pediatric Dermatology

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The COVID-19 pandemic has caused significant shifts in patient care including a steep decline in ambulatory visits and a marked increase in the use of telemedicine. Infantile hemangiomas (IH) can require urgent evaluation and risk stratification to determine which infants need treatment and which can be managed with continued observation. For those requiring treatment, prompt initiation decreases morbidity and improves long-term outcomes. The Hemangioma Investigator Group has created consensus recommendations for management of IH via telemedicine. FDA/EMAapproved monitoring guidelines, clinical practice guidelines, and relevant, up-to-date Pediatric Dermatology FRIEDEN Et al.

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Section: Potential Risks Associated With Betablocker Treatmentmentioning

confidence: 99%

Management of infantile hemangiomas during the COVID pandemic

Frieden

Püttgen

Drolet

et al. 2020

Pediatric Dermatology

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“…Regarding the initiation of propranolol, almost half of the respondents (46·2%, 114 of 247) mentioned that they performed electrocardiography, although it does not seem useful for routine screening, given the low probability of detecting a cardiological contraindication . In particular, oral propranolol does not seem to increase the risk of sudden infant death syndrome.…”

Section: Clinical Vignettes: Prescription Of Oral Propranolol Accordimentioning

confidence: 99%

Modalities of use of oral propranolol in proliferative infantile haemangiomas: an international survey among practitioners

et al. 2020

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Correspondence between pigmented lesions identified by melanoma patients trained to perform partner-assisted skin self-examination and dermatological examination. Cancer Epidemiol Biomarkers Prev 2015; 24:1247-53. 4 Robinson JK, Wayne JD, Martini MC et al. Early detection of new melanomas by patients with melanoma and their partners using a structured skin self-examination skills training intervention: a randomized clinical trial. JAMA Dermatol 2016; 152:979-85. 5 Hultgren BA, Turrisi R, Mallett KA et al. Influence of quality of relationship between patient with melanoma and partner on partnerassisted skin examination education: a randomized clinical trial.

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“…Consensus statements from the Australian Vascular Anomalies Network and Australian Paediatric Dermatology Group, American Paediatric Association, British Society for Peadiatric Dermatology and an European expert group all recommend oral propranolol as first line treatment for infantile haemangiomas . All of the above groups acknowledge to some extent that further research needs to be done given these guidelines are based on expert opinion and low‐quality evidence.…”

Section: Clinical Perspectivementioning

confidence: 99%