Oral precancer and cancer

López‐López, José; Omaña-Cepeda, Carlos; Jané‐Salas, Enric

doi:10.1016/j.medcle.2016.03.006

Cited by 4 publications

(3 citation statements)

References 51 publications

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“…Precancer describes the signs in a normal cell that could transform to cancer. ( Lopez-Lopez et al, 2015 ). searched pre-oral cancer lesion prevention keywords from 2005 to 2015 and clinical trials from January 2011 to 2015.…”

Section: Introductionmentioning

confidence: 99%

“…searched pre-oral cancer lesion prevention keywords from 2005 to 2015 and clinical trials from January 2011 to 2015. The authors referred to the less significant patterns between pre-oral cancer lesions and early diagnosis ( Lopez-Lopez, Omana-Cepeda and Jane-Salas, 2015 ). However, some oral conditions might present before oral cancer, such as erythroplakia, leukoplakia, lichen planus, and submucosal fibrosis ( Abati, Bramati, Bondi, Lissoni and Trimarchi, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

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Using CADD tools to inhibit the overexpressed genes FAP, FN1, and MMP1 by repurposing ginsenoside C and Rg1 as a treatment for oral cancer

Abouelwafa,

Ibrahim,

El-Hadidi

et al. 2023

Front. Mol. Biosci.

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Oral cancer is one of the most common cancer types. Many factors can express certain genes that cause the proliferation of oral tissues. Overexpressed genes were detected in oral cancer patients; three were highly impacted. FAP, FN1, and MMP1 were the targeted genes that showed inhibition results in silico by ginsenoside C and Rg1. Approved drugs were retrieved from the DrugBank database. The docking scores show an excellent interaction between the ligands and the targeted macromolecules. Further molecular dynamics simulations showed the binding stability of the proposed natural products. This work recommends repurposing ginsenoside C and Rg1 as potential binders for the selected targets and endorses future experimental validation for the treatment of oral cancer.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Using CADD tools to inhibit the overexpressed genes FAP, FN1, and MMP1 by repurposing ginsenoside C and Rg1 as a treatment for oral cancer

Abouelwafa,

Ibrahim,

El-Hadidi

et al. 2023

Front. Mol. Biosci.

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“…La importancia de su conocimiento radica en que el LPO es capaz de malignizar, siendo considerado como un trastorno o desorden potencialmente maligno. Las formas clínicas de presentación de esta entidad han sido estudiadas en la bibliografía, destacando las variedades papular, reticular, atrófica, ampollar, erosiva y en placa 5 . La variante reticular es la más frecuente apareciendo como una lesión blanca, lineal en forma estrellada, reticular o anular ligeramente sobreelevada, palpable denominadas estrías de Wickham y que no se desprenden al raspado.…”

Section: Introductionunclassified

Liquen plano oral. Reporte de un caso y revisión de la literatura

Leonardi¹,

Caciva²,

Piemonte³

et al. 2020

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El liquen plano oral (LPO) es una enfermedad mucocutánea crónica, de carácter inflamatorio, etiología desconocida y naturaleza autoinmune, en la que se produce una agresión por parte de los linfocitos T dirigida frente a las células basales del epitelio de la mucosa oral. El diagnóstico del LPO debe basarse en la observación clínica y confirmarse con la descripción de las características histopatológicas. Se presenta caso clínico de paciente femenina de 39 años de edad que acudió a consulta odontológica al Servicio de Estomatología de la Escuela de Odontología, de la Facultad de Ciencias de la Salud, Universidad Católica de Córdoba, por presentar múltiples lesiones blancas en la cavidad bucal de 1 año de evolución. La paciente manifiesta episodios de stress. Se realizó biopsia de tipo incisional y se envió a anatomía patológica donde se confirmó el diagnóstico de Liquen Plano Oral.

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Lesiones de la mucosa oral que requieren derivación para estudio

Gómez

2020

FMC - Formación Médica Continuada en Atención Primaria

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Oral precancer and cancer

Cited by 4 publications

References 51 publications

Using CADD tools to inhibit the overexpressed genes FAP, FN1, and MMP1 by repurposing ginsenoside C and Rg1 as a treatment for oral cancer

Using CADD tools to inhibit the overexpressed genes FAP, FN1, and MMP1 by repurposing ginsenoside C and Rg1 as a treatment for oral cancer

Liquen plano oral. Reporte de un caso y revisión de la literatura

Lesiones de la mucosa oral que requieren derivación para estudio

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