Oral post-treatment supplementation with a combination of glutamine, citrulline, and antioxidant vitamins additively mitigates jejunal damage, oxidative stress, and inflammation in rats with intestinal ischemia and reperfusion
Yu-Wen Chiu,
Chien-Hsing Lee,
Hui-Chen Lo
Abstract:Introduction
Intestinal ischemia and reperfusion (IIR) injury is closely associated with oxidative stress. Evidence shows that oral supplementation with glutamine and citrulline alleviates IIR-induced jejunal damage. We investigated the effects of a combination of glutamine, citrulline, and antioxidant vitamins on IIR-induced jejunal damage, oxidative stress, and inflammation.
Method
Male Wistar rats that underwent 60 min of superior mesenteric artery occlusion were orally administered glutamine plus citrull… Show more
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