Oral Mucus Extravasation Phenomenon with Myxoglobulosis

Schulman, Joshua M.; Jordan, Richard C.

doi:10.1111/cup.12392

Cited by 4 publications

(2 citation statements)

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“…Clinically, oral lesions present as painless, bluish swellings, and measure from 0.1 to 2 cm in diameter [4]. Mucous accumulation within the lumen of single organs, such as the appendix or gallbladder, is also termed a mucocele [3,4].…”

Section: Introductionmentioning

confidence: 99%

“…Whereas mucoceles commonly affect the minor glands of the oral cavity, SDCs typically form in ducts of major salivary glands as a result of mucin accumulation due to distal obstruction [2][3][4][5]. The clinical differential diagnosis of mucoceles and SDCs is broad and may include lipoma, hemangioma, lymphangioma, benign or malignant salivary gland neoplasms, venous varix, lymphoepithelial cyst, soft tissue abscess, and pyogenic granuloma [2,6,7].…”

Section: Introductionmentioning

confidence: 99%

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Laryngeal Myxoglobulosis: A Rare Histologic Variant of Mucocele. The First Reported Case

Krajinović

Fajdiga

Gale

2019

Head and Neck Pathol

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Myxoglobulosis is a rare histologic variant of mucocele that is characterized by transformation of mucin into eosinophilic globules. The globules frequently demonstrate a lamellar pattern and are surrounded by an inflammatory cell infiltrate. Myxoglobulosis has not yet been described in laryngeal mucosa. A 62 year old man presented for a check-up with hoarseness of 2 months duration. He was a current smoker and reported a 40 year habit. An asymmetrical swelling along the length of both vocal cords was consistent with a clinical diagnosis of Reinke's edema. The histopathologic examination demonstrated bilateral pseudocyst formation within Reinke's space. Extravasated mucin was present in the form of eosinophilic globules that filled the left Reinke's space almost entirely and were also seen on the right side. The pseudocyst, mucinous globules, and accompanying inflammatory cells were characteristic of myxoglobulosis. The sequelae of nicotine abuse, including inflammation, increased mucous secretion, and a rasping cough, are considered to be the main etiological factors of laryngeal myxoglobulosis. The patient had no evidence of voice disorder at 18 month follow-up. This case report contributes to the recognition of an exceptionally rare histologic variant of laryngeal mucocele.

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Section: Introductionmentioning

confidence: 99%