Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma

Ozga, Andrew T.; Sankaranarayanan, Krithivasan; Tito, Raúl Y.; Obregón-Tito, Alexandra J.; Foster, Morris W.; Tallbull, Gloria; Spicer, Paul; Warinner, Christina; Lewis, Cecil M.

doi:10.1002/ajpa.23033

Cited by 29 publications

(24 citation statements)

References 37 publications

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“…However, our fundamental understanding of contemporary microbiome alterations requires recognition of the current ascertainment bias; the majority of microbiome studies examine populations of European descent, who live industrialized lifestyles (Lewis et al, ; Warinner & Lewis, ). The little existing research on different ethnic populations has shown that there are taxonomic, compositional, and functional differences in the microbiomes of different human populations (Anwesh et al, ; Martínez et al, ; Ozga et al, ; Rampelli et al, ; Yatsunenko et al, ; Zhang et al, ). Therefore, it cannot be assumed that the same instigator will equally impact different microbiomes; dysbiosis may take different forms, provoking various disease responses.…”

Section: Discussionmentioning

confidence: 99%

Consequences of colonialism: A microbial perspective to contemporary Indigenous health

Skelly

Kapellas

Cooper

et al. 2018

American J Phys Anthropol

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Nearly all Indigenous populations today suffer from worse health than their non-Indigenous counterparts, and despite interventions against known factors, this health "gap" has not improved. The human microbiome-the beneficial, diverse microbial communities that live on and within the human body-is a crucial component in developing and maintaining normal physiological health. Disrupting this ecosystem has repercussions for microbial functionality, and thus, human health. In this article, we propose that modern-day Indigenous population health may suffer from disrupted microbial ecosystems as a consequence of historical colonialism. Colonialism may have interrupted the established relationships between the environment, traditional lifeways, and microbiomes, altering the Indigenous microbiome with detrimental health consequences.

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Section: Discussionmentioning

confidence: 99%

Consequences of colonialism: A microbial perspective to contemporary Indigenous health

Skelly

Kapellas

Cooper

et al. 2018

American J Phys Anthropol

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“…However, African populations were characterized by a less diverse saliva microbiome than rural individuals from Alaska or urban individuals from Germany 35 , thus opposite to the trends observed for the gut microbiome. Similarly, the saliva microbiome of Native Americans in Oklahoma had lower diversity than the microbiome of neighbouring more urbanized individuals of European descent 36 . Finally, Clemente et al 3 found no difference between the saliva microbiome of the isolated Yanomami population from Venezuela and individuals from the US (despite differences in their gut microbiome diversity), suggesting no effect of lifestyle.…”

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confidence: 99%

Response of the human gut and saliva microbiome to urbanization in Cameroon

Lokmer

Aflalo

Amougou

et al. 2020

Sci Rep

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Urban populations from highly industrialized countries are characterized by a lower gut bacterial diversity as well as by changes in composition compared to rural populations from less industrialized countries. to unveil the mechanisms and factors leading to this diversity loss, it is necessary to identify the factors associated with urbanization-induced shifts at a smaller geographical scale, especially in less industrialized countries. to do so, we investigated potential associations between a variety of dietary, medical, parasitological and socio-cultural factors and the gut and saliva microbiomes of 147 individuals from three populations along an urbanization gradient in cameroon. We found that the presence of Entamoeba sp., a commensal gut protozoan, followed by stool consistency, were major determinants of the gut microbiome diversity and composition. interestingly, urban individuals have retained most of their gut eukaryotic and bacterial diversity despite significant changes in diet compared to the rural areas, suggesting that the loss of bacterial microbiome diversity observed in industrialized areas is likely associated with medication. finally, we observed a weak positive correlation between the gut and the saliva microbiome diversity and composition, even though the saliva microbiome is mainly shaped by habitat-related factors.Humans living in urban areas from highly industrialized countries host less diverse gut microbiomes than those in rural areas from the less industrialized ones. This effect of industrialization (as we refer to it hereafter) has been reported by numerous studies comparing urban areas in Europe or North America with rural ones in Africa, Asia or South America 1-8 . Loss in alpha diversity is further accompanied by systematic shifts in bacterial composition (see e.g. 9,10 ). Despite crucial implications for human health 11,12 , the factors responsible for these ecological changes are still unclear. Two main (non-exclusive) hypotheses have been proposed: (i) decreased consumption of dietary fibers 13,14 and (ii) improved sanitation and access to medical care (including antibiotics 15 ). In addition, geographical latitude could be a confounding factor, given that it is a proxy for the diversity of environmental bacteria 16 . Indeed, the only two studies that did not find a loss of diversity with industrialization were studies considering rural populations not living in a warm tropical environment 17,18 .To disentangle various factors potentially leading to this observed diversity loss, some authors focused on smaller geographical scales, contrasting urban and rural individuals from the same countries (referred to hereafter as the effect of urbanization). Such studies reported inconsistent results: no significant differences in Russia 19 and Nigeria 20 , some differences in China 21 , and season and altitude dependent shifts in Mongolia 22 and India 23 , respectively. These discrepancies can be partially explained by different definitions of rural areas used in these studies (from iso...

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“…mutans GTs between two different populations separated by geography and ethnicity but with similar SES. However, a very recent paper compared the oral microbiome diversity among Cheyenne and Arapaho individuals in Oklahoma (Ozga, Sankaranarayanan, Tito, et al, ). While there was not an emphasis on S .…”

Section: Discussionmentioning

confidence: 99%

Genotypic characterization and comparison of Streptococcus mutans in American Indian and Southeast Iowa children

Villhauer

Lynch

Warren

et al. 2017

Clinical & Exp Dental Res

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Early childhood caries is a complex health care issue that has a multifactorial etiology. One aspect of this etiology is the colonization and propagation of acidogenic bacteria at an early age. There have been several bacterial species associated with caries but 1 common species is Streptococcus mutans. Here, we describe genotypic diversity and commonality of Streptococcus mutans recovered from children representing 2 groups with similar socioeconomic demographics: a Northern Plains American Indian Tribe and a Southeast Iowa population. Forty 36‐month‐old American Indian children were selected from a cohort of 239 mothers and children, and forty 2‐ to 5‐year‐old children from Southeast Iowa were selected to compare the genotypic profiles of Streptococcus mutans recovered from each child's plaque. S. mutans isolates were selected from whole mouth plaque samples; DNA was extracted and amplified via AP‐PCR to show specific genotype patterns. These patterns were compared with GelComparIIv6.5 gel analysis software. We found 18 distinct genotypes from 524 isolates; 13 of which were common between the 2 communities. Five genotypes were unique to only the American Indian children while the Southeast Iowa children harbored no unique genotypes. Although the American Indian children had some genotypes that were not present in the Southeast Iowa children, these were not widely distributed among the community. Furthermore, the levels of genotypic diversity and commonality were similar between the 2 populations. This study sets the groundwork for a comprehensive comparison of genotypes and caries among larger subsections of both populations.

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Oral microbiome diversity among Cheyenne and Arapaho individuals from Oklahoma

Cited by 29 publications

References 37 publications

Consequences of colonialism: A microbial perspective to contemporary Indigenous health

Consequences of colonialism: A microbial perspective to contemporary Indigenous health

Response of the human gut and saliva microbiome to urbanization in Cameroon

Genotypic characterization and comparison of Streptococcus mutans in American Indian and Southeast Iowa children

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