Oral manifestations in patients with neurofibromatosis type-1: A comprehensive literature review

Javed, Fawad; Ramalingam, Sundar; Ahmed, Hameeda Bashir; Gupta, Brijen K.; Sundar, Chalini; Qadri, Talat; Al‐Hezaimi, Khalid; Romanos, Georgios E.

doi:10.1016/j.critrevonc.2014.02.007

Cited by 65 publications

(64 citation statements)

References 58 publications

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“…Most articles considering NF1 describe missing teeth [4,6]. Hyperdontia is poorly described, especially as an isolated facial manifestation, as in this case report.…”

Section: Discussionmentioning

confidence: 82%

“…Many multisystemic complications such as cerebral tumors or vasculopathies could lead to death [1,2]. Oral and maxillofacial manifestations may also be found in patients with NF1, such as gingival enlargement and pigmentation, oral and perioral neurofibroma, osseous lesions of the maxilla or the mandible, and dental abnormalities [3][4][5][6][7][8][9][10][11][12].…”

Section: Introductionmentioning

confidence: 99%

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Neurofibromatosis type I and supernumerary teeth: up-to date review and case report

Cervellera

Dissaux³

2016

Med Buccale Chir Buccale

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-Introduction: Neurofibromatosis type I (NF1) is a genetic disease that may involve oral manifestations such as supernumerary teeth. Case report: A 17-year-old male patient with NF1 was referred by an orthodontist for avulsion of wisdom teeth and six supernumerary teeth. Ten teeth were removed under general anesthesia in December 2015. Discussion: Management of supernumerary teeth is very controversial and patient care of NF1 is complex. Conclusion: Even though the presence of supernumerary teeth in cases of NF1 is not well-known, patient care is extremely important and requires a team of specialists.Résumé -Les dents surnuméraires dans la neurofibromatose de type I : cas clinique et revue de la littéra-ture. Introduction : La neurofibromatose de type I est une maladie génétique qui peut induire des manifestations orales comme la présence de dents surnuméraires. Observation clinique : Un homme de 17 ans présentant une NF1 a été adressé par son orthodontiste pour l'avulsion de ses dents de sagesse et 6 dents surnuméraires. Les 10 dents ont été extraites sous anesthésie générale en décembre 2015. Discussion : La prise en charge des dents surnuméraires est très controversée et la prise en charge des patients atteints de NF1 est complexe. Conclusion : Même si la présence de dents surnuméraires chez les patients atteints de NF1 est mal connue, la prise en charge de ces patients est très importante et une équipe pluridisciplinaire est nécessaire.

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“…Most articles considering NF1 describe missing teeth [4,6]. Hyperdontia is poorly described, especially as an isolated facial manifestation, as in this case report.…”

Section: Discussionmentioning

confidence: 82%

Section: Introductionmentioning

confidence: 99%

Neurofibromatosis type I and supernumerary teeth: up-to date review and case report

Cervellera

Dissaux³

2016

Med Buccale Chir Buccale

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“…Los tumores en la NF casi siempre se encuentran en la lengua, pero otras regiones orales incluyen paladar, vestíbulo, mucosa bucal, labios, encías y el piso de la boca (18). En el caso de este paciente, además de la presencia de un neurofibroma en cavidad oral, no se cumplían otros criterios de NF, por lo que se consideró un neurofibroma solitario esporádico que además, por el sitio donde se ubicó, era probable que el nervio comprometido fuera el hipogloso.…”

Section: Discussionunclassified

Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

et al. 2018

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REPORTE DE CASO | Resumen |Se presenta el caso de un paciente masculino de 14 años de edad, con antecedente de dos intervenciones quirúrgicas debidas a la presencia de una masa a nivel sublingual -la primera a los 8 meses de edad y la segunda a los 13 años-y sin información de estudios histopatológicos. Cerca de 8 meses después de la última intervención quirúrgica es valorado por el Servicio de Cirugía Maxilofacial de la Fundación Hospital Pediátrico de La Misericordia en Bogotá D.C., Colombia, por crecimiento acelerado de la misma lesión y por problemas en la deglución y el lenguaje. En la revisión del paciente se encuentra una masa importante sublingual, dificultad en el lenguaje, deformidad mandibular y alteraciones en la mordida, por lo que se decide intervenir quirúrgicamente de nuevo. El resultado de la biopsia es un tumor mesenquimal benigno característico de neurofibroma, que por su ubicación sugiere probable compromiso del nervio hipogloso.Palabras clave: Neurofibroma; Nervio hipogloso; Neoplasia (DeCS).

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“…It is well known that periodontal inflammatory conditions are worse in immunocompromised individuals, cigarette smokers, and individuals chewing smokeless tobacco products [15,17,[22][23][24][25][26][27][28]. Moreover, it has also been reported that the outcomes of periodontal surgical interventions are compromised in tobacco smokers [29,30].…”

Section: Discussionmentioning

confidence: 99%

Comparison of an essential-oil-based oral rinse and chlorhexidine as adjuncts to scaling and root planing in the treatment of periodontal inflammation

Alshehri

Alshail

Aldosary

et al. 2015

IMAS

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Abstract:Objective: The aim of the present short-term follow-up study was to compare the effects of an essential oil (EO)-based oral rinse and chlorhexidine as adjuncts to scaling and root planing (SRP) in the treatment of periodontal inflammation. Methods: In Group-1, SRP was performed and participants were instructed to rinse with EO-based oral rinse; in Group-2, SRP was performed and participants were instructed to rinse with chlorhexidine; and in Group-3, SRP was performed and participants were instructed to rinse with water. Periodontal parameters (plaque index [PI], bleeding-on-probing [BOP], and probing pocket depth [PPD] ≥ 4 mm) were assessed at baseline and after 7 and 30 days. Results: In all groups, periodontal parameters (PI, BOP, and PPD ≥ 4 mm) were comparable at baseline. In Groups-1 and -2, there was a significant reduction in PI (P < 0.01), BOP (P < 0.01), and PD ≥ 4 mm after 7 days and 30 days of follow-up than baseline. In Group-3, there was a significant reduction in PI (P < 0.01) and BOP (P < 0.01) after 7 days of follow-up compared to baseline. There was no difference in periodontal parameters after 7 days and 30 days of follow-up in Groups-1 and -2. Conclusion: EO-based oral rinses and chlorhexidine digluconate (CHX) are acceptable adjuncts to SRP in the treatment of periodontal inflammation.

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Oral manifestations in patients with neurofibromatosis type-1: A comprehensive literature review

Cited by 65 publications

References 58 publications

Neurofibromatosis type I and supernumerary teeth: up-to date review and case report

Neurofibromatosis type I and supernumerary teeth: up-to date review and case report

Neurofibroma del hipogloso en un niño colombiano. Reporte de caso

Comparison of an essential-oil-based oral rinse and chlorhexidine as adjuncts to scaling and root planing in the treatment of periodontal inflammation

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