Oral Malignant Melanoma: A Case Report

Sen, Suman; Sen, Sheuli; Kumari, Manisha; Khan, Sufia; Singh, Subhasini

doi:10.14712/23362936.2021.20

Cited by 5 publications

(5 citation statements)

References 10 publications

(7 reference statements)

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“…Nine (9) patients affected by oral mucosal nevi (MN), 4 males and 5 females, were from 21 to 48 years old. The oral nevi onset was tissue-specific, as follows: on the gingiva (4 cases), on mucous membrane of the cheek (2 cases), on labial mucosa (1), alveolar ridge (1) and vermilion (1). All the reported lesions were safely removed without any relapse after 5 years.…”

Section: Resultsmentioning

confidence: 99%

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PReferentially Expressed Antigen in MElanoma (PRAME): preliminary communication on a translational tool able to early detect Oral Malignant Melanoma (OMM)

Cascardi¹,

Cazzato²,

Ingravallo³

et al. 2023

J. Cancer

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Oral malignant melanoma (OMM) has a prevalence less than 1% of all melanomas and it commonly develops on the oral mucosa following a slow and unspecific transformation of unstable melanocytic lesions, often resulting in a diagnostic delay. The marker PReferentially Expressed Antigen in MElanoma (PRAME) seems to be a valid tool to investigate the biological and histological nature of cutaneous melanocytic lesions, but to date its use to characterize pigmented lesions in the oral cavity is largely unexplored. The aim of this study was to create preliminary knowledge on the PRAME expression in OMM, and to compare its expression respect to other dysplastic pigmented lesions of the oral cavity. Interestingly, PRAME has been demonstrated to be reliable in the clinical conditions investigated in our pilot study; in fact, it has clearly differentiated the cases of Melanoma, which showed diffuse and intense positivity (score 6+/7+) to PRAME, from the other melanocytic nevi, which resulted to be mainly negative to PRAME. This means a better differential diagnosis, a reliable early diagnosis and a proper clinical/surgical management of the oncological lesions. In conclusion, PRAME can be a valid qualitative marker for differential diagnosis, not only in cutaneous melanomas, but also in malignant melanoma of the entire head and neck area.

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Section: Resultsmentioning

confidence: 99%

“…Oral Malignant Melanoma (OMM) is a rare variant of mucosal melanoma [1]. OMM epidemiology has recently showed an increased incidence within the Japan population; a predilection for the male sex seems to be generally reported, with a male/female ratio of 2:1 [2][3][4].…”

Section: Introductionmentioning

confidence: 99%

PReferentially Expressed Antigen in MElanoma (PRAME): preliminary communication on a translational tool able to early detect Oral Malignant Melanoma (OMM)

Cascardi¹,

Cazzato²,

Ingravallo³

et al. 2023

J. Cancer

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“…The Omaha system is a standardization system for nursing language that is composed of problem classification, intervention methods, and effectiveness scoring. The application of the Omaha system includes firsthand identification of problems, intervention measures, and evaluation outcome , and the patient's awareness towards their disease can be improved [9][10][11][12] . The continuous nursing system established based on the Omaha system alleviates the adverse psychological and physiological effects of the treatment through health education, counseling, rehabilitation programs, drug prescription, and dietary guidance, so that patients can have a good quality of life and positive outlook towards life [13][14][15] .…”

Section: Discussionmentioning

confidence: 99%

Analysis of the Effect of the Omaha-System-Based Continuous Nursing on Quality of Life of Patients with Oral Cancer

Tian

Huang

Wang

et al. 2023

JCNR

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Objective: To explore the advantages of continuous nursing based on the Omaha system for patients with oral cancer surgery. Methods: 120 cases patients who were treated surgically for oral cancer from January 2020 to June 2022 were selected for this study; the ages of patients ranged from 26–78 years old. The patients were divided into a control group (60 patients) who would undergo routine nursing and an observation group who would undergo continuous nursing based on the Omaha. Statistical analysis was carried out on the clinical data. Results: After nursing, the quality of life, degree of understanding towards the disease, total satisfaction, and total rate of effectiveness of the observation group were significantly higher than those of the control group, and the negative emotion scores were significantly lower in the observation group (P < 0.05). Conclusion: Continuous nursing based on the Omaha system can not only improve the quality of life of oral cancer patients after surgery, but also alleviate the negative emotions of patients, expand the degree of understanding towards the disease, and improve their overall quality of life. Besides, high rates of nursing satisfaction and total effectiveness can promote the postoperative recovery of patients.

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“… 1 Primary malignant melanoma of the esophagus (PMME) is extremely rare, predominantly affecting male patients aged 50–70 years and tends to be aggressive. 2 Primary melanomas of mucosal surfaces remain clinically silent for a long time, often detected in late stages with metastasis and has average life expectancy of <15 months at the time of diagnosis. 3 We present a case of PMME in a middle-aged man presenting with dysphagia and weight loss.…”

Section: Introductionmentioning

confidence: 99%

A Rare Case of Primary Malignant Melanoma of the Esophagus Presenting as Dysphagia

Chaudhry,

Buluku,

Noor

et al. 2024

ACG Case Rep J

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Melanoma is one of the most notorious tumors due to its appearance in unusual locations. The most frequent site is the skin; however, it can sporadically develop as a primary tumor in the esophagus. However, as symptoms appear later, if the primary site is in the gastrointestinal system, it is frequently detected at the metastatic stage. We hereby describe a case of primary malignant melanoma of the esophagus that presented due to dysphagia with solid food and on further workup, found to be at the metastatic stage.

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Oral Malignant Melanoma: A Case Report

Cited by 5 publications

References 10 publications

PReferentially Expressed Antigen in MElanoma (PRAME): preliminary communication on a translational tool able to early detect Oral Malignant Melanoma (OMM)

PReferentially Expressed Antigen in MElanoma (PRAME): preliminary communication on a translational tool able to early detect Oral Malignant Melanoma (OMM)

Analysis of the Effect of the Omaha-System-Based Continuous Nursing on Quality of Life of Patients with Oral Cancer

A Rare Case of Primary Malignant Melanoma of the Esophagus Presenting as Dysphagia

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