Oral lichen planus after COVID-19, a case report

Saleh, Wafaa; SHawky, Eman; Halim, Ghady Abdel; Ata, Fatma

doi:10.1016/j.amsu.2021.103051

Cited by 17 publications

(26 citation statements)

References 15 publications

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“…Reports of lichen planus onset following SARS‐CoV‐2 infection have demonstrated that the cases had occurred up to 1 month after the infection. 4 , 26 On the other hand, the few reports of lichen planus following SARS‐CoV‐2 vaccination had occurred about 1–2 weeks after receiving the vaccines. 3 , 27 , 28 In a repeated and more thorough history taking, the patient recalled some faint and scares lesions arising a few days following her first vaccine dose on her both ankles, which faded away, and recurred soon after the second vaccine dose with a more robust appearance, so as obliging her to seek physician visits.…”

Section: Discussionmentioning

confidence: 99%

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COVID‐19 vaccine‐related new‐onset lichen planus

Babazadeh

Miladi

Barary

et al. 2022

Clinical Case Reports

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Coronavirus disease 2019 (COVID‐19) vaccines significantly impacted world health and well‐being. However, various adverse events have been observed following severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccination. Cutaneous reactions have been prevalent following many vaccines, including COVID‐19 vaccines. Here, we present a case of new‐onset lichen planus in a patient who received the COVID‐19 vaccine at the same time as being infected with SARS‐CoV‐2. A 52‐year‐old woman presented to the clinic with extensive pruritic skin lesions. The eruptions had appeared a week after her second dose of the Sinopharm COVID‐19 vaccine. She mentioned a history of SARS‐CoV‐2 infection approximately 10 days following the first dose of her vaccine, causing a 1‐month delay in getting the second dose. Her past medical history was not significant. On examination, erythematous and squamous papules were demonstrated predominantly on the extremities, including inguinal and axillary folds. Moreover, desquamation of the lips was visible, and buccal lesions were also found. After consultation with a dermatologist, a skin biopsy was indicated for the patient, but she refused to undergo the procedure. Therefore, considering the typical appearance of the eruptions, lichen planus was suspected, for which she was treated with oral antihistamines and topical corticosteroids.

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Section: Discussionmentioning

confidence: 99%

“… 1 , 2 Nonetheless, lichen planus has been reported less commonly after SARS‐CoV‐2 infection or COVID‐19 vaccination, necessitating its careful discussion. 3 , 4 Here, we present a case of new‐onset lichen planus in a patient who received the COVID‐19 vaccine at the same time as being infected with SARS‐CoV‐2.…”

Section: Introductionmentioning

confidence: 98%

COVID‐19 vaccine‐related new‐onset lichen planus

Babazadeh

Miladi

Barary

et al. 2022

Clinical Case Reports

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“…Since our patient got infected with the virus in the meantime between the two doses of the vaccines, it is difficult to determine whether she developed this dermatologic disease due to SARS-CoV-2 infection or as a consequence of its vaccines. Reports of lichen planus onset following SARS-CoV-2 infection have demonstrated that the cases had occurred up to one month after the infection [4,26]. On the other hand, the few reports of lichen planus following SARS-CoV-2 vaccination had occurred about one to two weeks after receiving the vaccines [3,27,28].…”

Section: Discussionmentioning

confidence: 99%

“…Psoriasis and seborrheic dermatitis are among the most common long-lasting dermatologic disorders triggered or flared up following this viral infection or related vaccines [1,2]. Nonetheless, lichen planus has been reported less commonly after SARS-CoV-2 infection or COVID-19 vaccination, necessitating its careful discussion [3,4]. Here, we present a case of new-onset lichen planus in a patient who received the COVID-19 vaccine at the same time as being infected with SARS-CoV-2.…”

Section: Introductionmentioning

confidence: 99%

COVID-19 vaccine-related new-onset lichen planus

Babazadeh

Miladi

Barary

et al. 2021

Preprint

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“…F [ 28 ] (Hertel et al) Vaccination Tozinameran, 2nd dose 14 days Upper and lower vestibules Unspecified Unspecified 63-y.o. M [ 29 ] (Saleh et al) Infection N/A 30–31 days Oral mucosa Topical corticosteroids 3 times daily for 10 days followed by a symptom-dependent taper Marked improvement after 4 weeks (decreased pain and size of lesions) 41-y.o. M [ 10 ] (Alabdulaaly et al) Infection N/A 14 days Bilateral buccal mucosa and gingival margins Fluocinonide 0.05% gel Resolution in 1 month 56-y.o.…”

Section: Appendixmentioning

confidence: 99%

Lichen planus after COVID-19 infection and vaccination

Zou

Daveluy

2022

Arch Dermatol Res

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Lichen planus (LP) is an inflammatory disorder believed to result from CD8 + cytotoxic T -cell (CTL)-mediated autoimmune reactions against basal keratinocytes. We present a review of LP following COVID-19 infection and vaccination. Literature searches were conducted on PubMed and Google Scholar from 2019 to 7/2022. 36 articles were selected based on subject relevance, and references within articles were also screened. 39 cases of post-vaccination LP and 6 cases of post-infection LP were found among case reports and case series. 152 cases of post-vaccination LP and 12 cases of post-infection LP were found in retrospective and prospective studies. LP is a rare complication of COVID-19 infection and vaccination that may be mediated by overstimulation of T -cell responses and proinflammatory cytokine production. However, it does not represent a limitation against COVID-19 vaccination, and the benefits of vaccination considerably outweigh the risks.

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Oral lichen planus after COVID-19, a case report

Cited by 17 publications

References 15 publications

COVID‐19 vaccine‐related new‐onset lichen planus

COVID‐19 vaccine‐related new‐onset lichen planus

COVID-19 vaccine-related new-onset lichen planus

Lichen planus after COVID-19 infection and vaccination

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