Oral lesions in elderly population: a biopsy survey using 2250 histopathological records

Corrêa, Luciana; Frigerio, Maria; Sousa, Suzana Cantanhede Orsini Machado de; Novelli, Moacyr Domingos

doi:10.1111/j.1741-2358.2006.00090.x

Cited by 57 publications

(143 citation statements)

References 20 publications

(40 reference statements)

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“…Roopashree et al; Gupta & Jawanda). The clinical findings showed that women were the most affected gender, which is in agreement with other reports (Roopashree et al;Wang et al;Coelho et al, 2000;Corrêa et al, 2006;. Regarding age, patients older than 40 years were the major group, consistent with Carvalho et al The main affected site was jugal mucosa, as mentioned by others studies in Brazil and different countries (Fernández-González et al, 2010;Oliveira Alves et al, 2010;Werneck et al, 2015).…”

Section: Discussionsupporting

confidence: 82%

Oral Lichen Planus: Clinical Profile and Determination of Oral Epithelial Dysplasia

Paiva

Braga

Almeida-Coburn

et al. 2016

Int. J. Odontostomat.

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ABSTRACT:Oral lichen planus (OLP) is the most common noninfectious oral disease and is considered a potentially malignant disorders (OPMDs). The etiology and pathogenesis of OLP are not completely understood and the malignant transformation remains under discussion. The aim was to asses the cytological and histological features of OLP, and establish relationship between clinical and microscopic profiles. A total of 10 patients diagnosed with OLP were investigated. Slides were prepared and stained with Hematoxylin-Eosin to identify 8 histological features and 8 cytological alterations. Finally, oral epithelial dysplasia degree was determined. Hyperplasia and loss of polarity of basal cells were detected in 90 % of cases. Anisonucleosis, nuclear pleomorphism and hyperchromasia affected 100 % of the sample. Six cases were classified as mild-grade OED, with no cases of severe-grade. Microscopic alterations were higher in women (P <0.0001) and moderategrade OED was diagnosed only in this group (P <0.0014). The findings demonstrated that microscopic and clinical data association should be analyzed to a better understand of disease behavior. OED was absence only in one case, so the periodic follow-up of patients diagnosed with OLP is mandatory to avoid the malignant transformation.KEY WORDS: oral epithelial dysplasia, oral lichen planus, potentially malignant disorders.

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Section: Discussionsupporting

confidence: 82%

Oral Lichen Planus: Clinical Profile and Determination of Oral Epithelial Dysplasia

Paiva

Braga

Almeida-Coburn

et al. 2016

Int. J. Odontostomat.

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“…Correa et al reported a higher incidence of epithelial malignant and premalignant conditions, autoimmune diseases, and salivary gland tumors in an elderly population in Brazil. In their study, inflammatory fibrous hyperplasia, squamous cell carcinoma (SCC) and fibroma were the most common lesions (4). A similar survey in Finland revealed a higher incidence of premalignant lesions and radicular cysts in elderlies (5).…”

Section: Introductionmentioning

confidence: 94%

Oraland Maxillofacial Lesions in an Elderly Population in Shiraz, Iran

Pardis¹,

Taheri²,

Fani³

2014

Avicenna J Dent Res

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Background: Aging causes many changes in human physiology, increasing the risk of pathologic conditions in elderly populations. Different studies have shown higher frequency of oral and maxillofacial lesions in older people. Knowing the prevalence and distribution of these lesions can help dentists in screening these patients. Objectives: This study aimed to evaluate the frequency and distribution of oral pathologic lesions among patients referred to Oral Pathology Department of Shiraz Dental School. Patients and Methods: By referring to archives of Oral Pathology Department of Shiraz University of Medical Sciences, the histopathological reports of all 231 patients aged 60 years or over were reviewed. The data were described and analyzed using SPSS software. Chi-square test was performed and a P value less than 0.05 was considered significant. Results: The most prevalent lesion was oral lichen planus (21.6%), followed by inflammatory fibrous hyperplasia (15.8%) and squamous cell carcinoma (7.6%). There was a statistically significant difference between men and women in the occurrence of odontogenic cysts and dermatologic diseases. (P = 0.018 and 0.002, respectively;chi-square = 5.63 and 9.47, respectively). Moreover, non-neoplastic lesions were the most prevalent group of lesions in this study. Conclusions: High frequency of life-threatening oral conditions among elderly populations makes it essential for dentists to pay special attention to the most frequent lesions and help enhance the life quality of elderlies by early diagnosis and management of these diseases.

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“…O tipo histológico mais prevalente foi o carcinoma epidermóide nos dois anos estudados (Tabela 1) com 72,7% dos casos de câncer de boca, em consonância com os estudos de Gervásio et al 21 e Corrêa et al 13 . Oliveira et al 3 analisaram o perfil epidemiológico da cidade de São Paulo entre 1997 e 1999 e tiveram a mesma constatação, o mesmo ocorrendo no Chile, onde 90% dos casos de câncer de boca também corresponderam ao carcinoma epidermóide 14 .…”

Section: Metodologiaunclassified

Epidemiologia do câncer de boca em laboratório público do Estado de Mato Grosso, Brasil

Borges¹,

Garbín

Carvalhosa³

et al. 2008

Cad. Saúde Pública

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O objetivo deste trabalho foi analisar a epidemiologia do câncer de boca, dos casos diagnosticados pelo laboratório público do Estado de Mato Grosso, Brasil, após a instituição da política de atenção às doenças da boca e da face do estado. Trata-se de um estudo epidemiológico transversal. O objeto estudado foi o laudo histopatológico, pesquisando-se um total de 1.324 laudos emitidos entre janeiro de 2005 e dezembro 2006. Verificaram-se os casos de câncer de boca, o seu percentual em relação ao universo das lesões bucais e as seguintes variáveis: tipo histológico, sexo, idade e procedência dos pacientes (capital ou do interior). Após a análise dos dados verificaram-se 44 lesões de câncer de boca, representando 3% dos diagnósticos. O tipo histológico mais incidente foi o carcinoma epidermóide. A maioria dos diagnósticos foi referente aos homens na 5ª e 6ª décadas de vida residentes no interior do estado. Conclui-se com este estudo que em dois anos de funcionamento o serviço público de patologia bucal registrou um considerável número de casos de câncer de boca.

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Oral lesions in elderly population: a biopsy survey using 2250 histopathological records

Abstract: The distribution of oral diseases using biopsies allows greater accuracy in data about oral health of elderly patients, especially when considering malignant and pre-malignant lesions.

Cited by 57 publications

References 20 publications

Oral Lichen Planus: Clinical Profile and Determination of Oral Epithelial Dysplasia

Oral Lichen Planus: Clinical Profile and Determination of Oral Epithelial Dysplasia

Oraland Maxillofacial Lesions in an Elderly Population in Shiraz, Iran

Epidemiologia do câncer de boca em laboratório público do Estado de Mato Grosso, Brasil

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