Oral Leiomyomatous Hamartoma of the Median Maxillary Gingiva

Alqahtani, Dalal Abdullah; Qannam, Ahmed

doi:10.1177/1066896912471852

Cited by 10 publications

(9 citation statements)

References 11 publications

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“…During the embryonic development, fusion of several tissues has been considered due to the predilection of such occurrence at the base of the tongue and upper median gingiva 6 9 10. These remain inconspicuous at birth and are apparent when they enlarge rapidly following a traumatic episode.…”

Section: Discussionmentioning

confidence: 99%

Gingival leiomyomatous hamartoma of the maxilla: a rare entity

2016

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Hamartoma is a tumour-like malformation appearing as a focal overgrowth of normal cells. Leiomyomatous hamartomas (LHs) are rare in the oral cavity and commonly seen in the Japanese and less than 40 cases have been reported in the Japanese and English literature. The clinical differential diagnoses are irritational (traumatic) fibroma and congenital epulis. It has to be differentiated histopathologically from its neoplastic counterparts and mesenchymomas. Hence, we report such a case of LHs, which presented as a sessile gingival growth occurring in the midline in a 15-year-old girl. The final diagnosis was based on the histopathological appearance which was confirmed by immunohistochemical staining of various markers. A review of the literature of previous cases was also carried out.

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Section: Discussionmentioning

confidence: 99%

Gingival leiomyomatous hamartoma of the maxilla: a rare entity

2016

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“…The term hamartoma is used to describe a nonneoplastic, abnormal, and haphazard overgrowth of conglomerates of mature cells and tissues indigenous to the anatomic site from which it occurs, often with one predominating element [ 1 , 2 ]. This tumor-like malformation is benign, and most hamartomas are located in the liver, spleen, pancreas, and kidneys [ 3 ]. Oral hamartomas are rare [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…This tumor-like malformation is benign, and most hamartomas are located in the liver, spleen, pancreas, and kidneys [ 3 ]. Oral hamartomas are rare [ 3 ]. An oral leiomyomatous hamartoma, as the name suggests, is therefore a lesion composed mostly of smooth-muscle tissue.…”

Section: Introductionmentioning

confidence: 99%

“…An oral leiomyomatous hamartoma, as the name suggests, is therefore a lesion composed mostly of smooth-muscle tissue. They typically present as smooth, soft, nodular lesions that are present at birth and further develop in the first decade of life [ 3 ]. They are usually painless masses without obvious symptoms [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

“…They are usually painless masses without obvious symptoms [ 1 ]. In most of the published reports, manifestations have commonly been on the gingiva, tongue, and hard palate, specifically the dorsum of the tongue and the anterior maxillary gingiva or alveolar ridge in the incisive papilla region [ 1 , 3 ]. Due to its low clinical morbidity and nonspecific symptoms, diagnosis and treatment remains a challenge [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

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Lingual Leiomyomatous Hamartoma in an Adult Male

Nguyen

Firth

Mougos³

et al. 2018

Case Reports in Dentistry

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An otherwise healthy 20-year-old male presented with an exophytic, polypoid, yellowish lesion involving the dorsal surface of his tongue, which he reported being present since birth and unchanged. This was removed by surgical excision and diagnosed as a leiomyomatous hamartoma. Histological examination revealed a combination of fibrovascular connective tissue, conspicuous smooth-muscle bundles, adipose tissue, minor salivary gland tissue, blood vessels, lymphoid tissue, peripheral nerves, and normal skeletal muscle. This case is exceptional due to the patient's age, as until now, lingual leiomyomatous hamartomas have been reported almost exclusively in a paediatric population. To our knowledge, this is the eldest age at which a LLH has been reported in the literature. This underscores the need for clinicians to consider this rarely reported entity when considering the radiographic and clinical differential diagnoses for these lesions, both in the paediatric and adult populations. We also present a review of the literature regarding lingual leiomyomatous hamartomas.

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Hamartoma of the Oral Cavity with Ectopic Meningothelial Elements in Infants: A Rare Entity with Report of Two Cases

Tekkeşın

Chiosea

Ozolek

2019

Head and Neck Pathol

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Choristomas and hamartomas within the oral cavity are relatively uncommon lesions and may present with diverse clinical and histopathological appearances. In this report, we describe two infant patients with hamartoma with ectopic meningothelial elements involving tongue and maxillary alveolar ridge. To the best of our knowledge, these are the first two cases in which a meningothelial proliferation has been identified in the oral cavity. Hamartoma with ectopic meningothelial elements is a rare condition that has been classically described occurring in the scalp. These lesions are characterized by bland round to spindle-shape cells that interdigitate through collagen bundles and express progesterone receptor and epithelial membrane antigen by immunohistochemistry supporting a meningothelial origin.

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Oral Leiomyomatous Hamartoma of the Median Maxillary Gingiva

Cited by 10 publications

References 11 publications

Gingival leiomyomatous hamartoma of the maxilla: a rare entity

Gingival leiomyomatous hamartoma of the maxilla: a rare entity

Lingual Leiomyomatous Hamartoma in an Adult Male

Hamartoma of the Oral Cavity with Ectopic Meningothelial Elements in Infants: A Rare Entity with Report of Two Cases

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