Oral Kaposi Sarcoma Associated with Severe Alveolar Bone Loss: Case Report and Review of the Literature

Lausten, Leonard; Ferguson, Brett L.; Barker, Bruce F.; Cobb, Charles M.

doi:10.1902/jop.2003.74.11.1668

Cited by 24 publications

(29 citation statements)

References 53 publications

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“…30,31 Effective dental management, however, is fundamental to the overall care and health of these patients. Significant advances in understanding the pathogenesis and progression of this disease will ultimately lead to improved care of this patient population.…”

Section: 2mentioning

confidence: 99%

Systemic disorders and their influence on the development of dental hard tissues: A literature review

Atar¹,

Körperich²

2010

Journal of Dentistry

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Section: 2mentioning

confidence: 99%

Systemic disorders and their influence on the development of dental hard tissues: A literature review

Atar¹,

Körperich²

2010

Journal of Dentistry

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“…Histopathologic evaluation is necessary to achieve a definitive diagnosis . The oral biopsy procedure is simple and safe, but specimens should be of sufficient thickness to include connective tissue …”

Section: Diagnosismentioning

confidence: 99%

Oral Kaposi's sarcoma: a review and update

Fatahzadeh

Schwartz

2013

Int J Dermatology

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Kaposi's sarcoma (KS) is an important mucocutaneous neoplasm with four well-known clinicopathologic types. Involvement of the oral cavity may be seen in all variants but is most common with AIDS-KS. The latter may signal undiagnosed HIV infection. Its common association with disseminated disease has potentially important diagnostic and therapeutic implications. Oral KS (OKS) most often affects the hard and soft palate, gingiva, and dorsal tongue with plaques or tumors of coloration ranging from non-pigmented to brownish-red or violaceous. Its involvement ranges from an incidental finding to proliferative tumor formation that interferes with mastication. OKS needs to be distinguished clinically from other entities, including pyogenic granuloma, hemangioma, bacillary angiomatosis, and gingival enlargement caused by cyclosporine, a drug frequently used in recipients of organ transplantation. KS may flare as part of the immune reconstitution inflammatory syndrome in HIV patients or develop in the context of iatrogenic immunosuppression. Management, which may depend upon a variety of factors including the clinicopathologic type of KS and results of staging, ranges from no treatment to local measures such as intralesional vinblastine or systemic administration of cytotoxic chemotherapy for disseminated disease. Modification of immunosuppressive regimens often helps control post-transplant OKS but enhances the risk of graft rejection. Screening donors and recipients of organ transplants for HHV-8, with prophylactic treatment if infected as well as institution of sirolimus early after transplantation, are proposed strategies aimed at preventing post-transplant OKS.

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“…Elles sont parfois le siège d'une surinfection mycosique ou bactérienne. Quelquefois, on observe des mobilités dentaires et une lyse osseuse [20].…”

Section: Cliniqueunclassified

“…Pour les lésions buccales isolées au stade tumoral, les parties molles adjacentes sont le plus souvent respectées et la lyse osseuse sous-jacente reste exceptionnelle [20]. Le bilan d'extension générale est systématique mais il est mal codifié : il est le plus souvent guidé par les signes d'appel cliniques [21].…”

Section: Radiologie Et Bilan D'extensionunclassified

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Sarcome de Kaposi buccal post-transplantation rénale : présentation d’un cas et revue de la littérature

Hasna

Slama

Sahtout

et al. 2013

Med Buccale Chir Buccale

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Résumé -Abstract -Oral Kaposi sarcoma after renal transplantation: a case report and review of literature. The immunosuppressive therapies are associated with an increase in the risk of Kaposi sarcoma among transplant patients. The management of these tumours is challenging as the immunosuppression must be monitored to prevent a potential transplant rejection. In 2009, a 48-year-old patient was referred to us by the nephrology department for a suspicious palatal lesion. The patient having had a renal transplantation in 2008 was under immunosuppressants. The intra-oral examination revealed a right red-purple palatal swelling, of 2.5 cm in long axis, painless, with firm consistency on palpation. The buccal vestibule was clear. No satellite adenopathy was observed. A biopsy revealed Kaposi sarcoma. An assessment of the local and general extension concluded an absence of an underlying osseous involvement as well as other remote locations. The treatment consisted of a modification of immunosuppressants associated with tumor resection surgery. The loss of mucous substance was repaired by an advanced vestibular flap and rotational palatal flap. The histology confirmed the diagnosis of Kaposi sarcoma and the limits of curative surgery. A 14-month follow-up showed a favorable evolution. Local and regional monitoring did not reveal any recurrence signs; this was confirmed by CTscan follow-up examination. Subsequently, the patient underwent a prosthetic restoration by means of a removable partial denture.

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Oral Kaposi Sarcoma Associated with Severe Alveolar Bone Loss: Case Report and Review of the Literature

Cited by 24 publications

References 53 publications

Systemic disorders and their influence on the development of dental hard tissues: A literature review

Systemic disorders and their influence on the development of dental hard tissues: A literature review

Oral Kaposi's sarcoma: a review and update

Sarcome de Kaposi buccal post-transplantation rénale : présentation d’un cas et revue de la littérature

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