Oral iron supplements for children in malaria-endemic areas

Abstract

Iron alone or with antimalaria treatment does not increase the risk of clinical malaria or death when regular malaria surveillance and treatment services are provided. There is no need to screen for anaemia prior to iron supplementation.

Effect of Iron Supplementation in the Prevention of Anemia Associated with Malaria in Children Aged 6 to 59 Months in Bakperou (Benin) in 2013

“…These facts are in support of a possibility of iron supplementation in order to improve the iron supplementation status of these children in the contrary to WHO guidelines who contraindicate iron supply in such children [22] especially in rural settings. The same conclusion has been drawn by Okebe et al in malaria endemic areas [20].…”

Effect of Iron Supplementation in the Prevention of Anemia Associated with Malaria in Children Aged 6 to 59 Months in Bakperou (Benin) in 2013

“…These facts are in support of a possibility of iron supplementation in order to improve the iron supplementation status of these children in the contrary to WHO guidelines who contraindicate iron supply in such children [22] especially in rural settings. The same conclusion has been drawn by Okebe et al in malaria endemic areas [20].…”

Iron Supplementation in Iron-Replete and Nonanemic Pregnant Women in Tanzania

“…A systematic review demonstrated that risk associated with iron supplementation in children was increased in trials where malaria control interventions and treatment were not available, such as the Pemba trial. 34 Regular use of malaria interventions at home had wide coverage in our study participants (>90%) and all women enrolled in our study were given IPTp-SP at the second and third trimesters. This high coverage of malaria prevention measures, coupled with the non-anemic, iron-replete baseline status of our participants, are likely to be important factors that explain the difference in findings between our trial and the Pemba study.…”

Effect of Short-Term Supplementation with Ready-to-Use Therapeutic Food or Micronutrients for Children after Illness for Prevention of Malnutrition: A Randomised Controlled Trial in Nigeria

“…Literature has suggested that iron supplements might worsen the outcome of malaria episodes [ 37 ] [ 38 ]. A review that was published before the start of our study and a later review did not confirm negative effects of iron supplementation on the outcome of malaria [ 39 , 40 ]. The mean number of diagnosed malaria events was higher in MNP group than in the RUTF group ( p = 0.051).…”

Effect of Iron Supplementation in the Prevention of Anemia Associated with Malaria in Children Aged 6 to 59 Months in Bakperou (Benin) in 2013

“…These facts are in support of a possibility of iron supplementation in order to improve the iron supplementation status of these children in the contrary to WHO guidelines who contraindicate iron supply in such children [22] especially in rural settings. The same conclusion has been drawn by Okebe et al in malaria endemic areas [20].…”

Iron Supplementation in Iron-Replete and Nonanemic Pregnant Women in Tanzania

“…A systematic review demonstrated that risk associated with iron supplementation in children was increased in trials where malaria control interventions and treatment were not available, such as the Pemba trial. 34 Regular use of malaria interventions at home had wide coverage in our study participants (>90%) and all women enrolled in our study were given IPTp-SP at the second and third trimesters. This high coverage of malaria prevention measures, coupled with the non-anemic, iron-replete baseline status of our participants, are likely to be important factors that explain the difference in findings between our trial and the Pemba study.…”

Effect of Short-Term Supplementation with Ready-to-Use Therapeutic Food or Micronutrients for Children after Illness for Prevention of Malnutrition: A Randomised Controlled Trial in Nigeria

“…Literature has suggested that iron supplements might worsen the outcome of malaria episodes [ 37 ] [ 38 ]. A review that was published before the start of our study and a later review did not confirm negative effects of iron supplementation on the outcome of malaria [ 39 , 40 ]. The mean number of diagnosed malaria events was higher in MNP group than in the RUTF group ( p = 0.051).…”

Effect of Iron Supplementation in the Prevention of Anemia Associated with Malaria in Children Aged 6 to 59 Months in Bakperou (Benin) in 2013

“…These facts are in support of a possibility of iron supplementation in order to improve the iron supplementation status of these children in the contrary to WHO guidelines who contraindicate iron supply in such children [22] especially in rural settings. The same conclusion has been drawn by Okebe et al in malaria endemic areas [20].…”

Iron Supplementation in Iron-Replete and Nonanemic Pregnant Women in Tanzania

“…A systematic review demonstrated that risk associated with iron supplementation in children was increased in trials where malaria control interventions and treatment were not available, such as the Pemba trial. 34 Regular use of malaria interventions at home had wide coverage in our study participants (>90%) and all women enrolled in our study were given IPTp-SP at the second and third trimesters. This high coverage of malaria prevention measures, coupled with the non-anemic, iron-replete baseline status of our participants, are likely to be important factors that explain the difference in findings between our trial and the Pemba study.…”

Effect of Short-Term Supplementation with Ready-to-Use Therapeutic Food or Micronutrients for Children after Illness for Prevention of Malnutrition: A Randomised Controlled Trial in Nigeria

“…Literature has suggested that iron supplements might worsen the outcome of malaria episodes [ 37 ] [ 38 ]. A review that was published before the start of our study and a later review did not confirm negative effects of iron supplementation on the outcome of malaria [ 39 , 40 ]. The mean number of diagnosed malaria events was higher in MNP group than in the RUTF group ( p = 0.051).…”