Oral Intake of<i>Lactobacillus helveticus</i>-Fermented Milk Whey Decreased Transepidermal Water Loss and Prevented the Onset of Sodium Dodecylsulfate-Induced Dermatitis in Mice

Baba, Hidehiko; Masuyama, Akihiro; Yoshimura, Chiaki; Aoyama, Yoshiko; Takano, Toshiaki; Ohki, Kohji

doi:10.1271/bbb.90370

Cited by 33 publications

(26 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the present study, the daily topical application of 50 μl of 10% SDS gradually increased dermatitis, reduced SC hydration, increased TEWL, and increased skin surface pH over a 4-day treatment period. The degree of decreased SC hydration and increased TEWL was milder in this study than in another report, in which 500 μl of 10% SDS in 70% ethanol was topically applied once daily for 4 days in hairless HR-1 mice (11). SDS application in our study gradually increased hindpaw scratching, as examined 22-24 h after each SDS application, which may therefore be due to changes in cutaneous conditions rather than surfactant irritation.…”

Section: Discussioncontrasting

confidence: 53%

“…Sodium dodecyl sulphate (SDS), a neutral anionic surfactant found in many shampoos and cleansers, causes irritant reactions in human and animal skin (9)(10)(11). Repeated topical application of 10% SDS induces various adverse skin reactions, such as dermatitis, skin dryness, and barrier disruption (11).…”

mentioning

confidence: 99%

“…Repeated topical application of 10% SDS induces various adverse skin reactions, such as dermatitis, skin dryness, and barrier disruption (11). In this study, we first examined whether the repeated topical application of 10% SDS would cause pruritus in mice, and next determined whether histamine released from mast cells and/or keratinocytes would be involved in the pruritogenic action of SDS.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Surfactant-induced Chronic Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis

Inami¹,

Sasaki²,

Andoh³

et al. 2014

Acta Derm Venerol

View full text Add to dashboard Cite

Shampoo and cleansers containing anionic surfactants including sodium dodecyl sulphate (SDS) often cause pruritus in humans. Daily application of 1-10% SDS for 4 days induced hind-paw scratching (an itch-related behaviour) in a concentration-dependent manner, and 10% SDS also caused dermatitis, skin dryness, barrier disruption, and an increase in skin surface pH in mice. SDS-induced scratching was inhibited by the opioid receptor antagonist naloxone and the H histamine receptor antagonist terfenadine. Mast-cell deficiency did not inhibit SDS-induced scratching, although it almost completely depleted histamine in the dermis. Treatment with SDS increased the histamine content of the epidermis, but not that of the dermis. SDS treatment increased the gene expression and post-translation processing of L-histidine decarboxylase in the epidermis. The present results suggest that repeated application of SDS induces itch through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.

show abstract

Section: Discussioncontrasting

confidence: 53%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Surfactant-induced Chronic Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis

Inami¹,

Sasaki²,

Andoh³

et al. 2014

Acta Derm Venerol

View full text Add to dashboard Cite

show abstract

“…Measurement of the skin moisture content, transepidermal water loss (TEWL) and erythema dose. All three factors related to skin homeostasis were assessed on the dorsal skin of each mouse using the appropriate devices (20). TEWL was detected using a Corneometer CM825 (Courage and Khazaka Electronics, Cologne, Germany).…”

Section: Methodsmentioning

confidence: 99%

UV radiation-induced skin aging in hairless mice is effectively prevented by oral intake of sea buckthorn (Hippophae rhamnoides L.) fruit blend for 6 weeks through MMP suppression and increase of SOD activity

Hwang

Kim

Choi

et al. 2012

International Journal of Molecular Medicine

View full text Add to dashboard Cite

Oxidative stress and oxidative photodamage induced by UV radiation can cause serious skin damage that is characterized by wrinkling, roughness, laxity and pigmentation. The effects of a sea buckthorn (Hippophae rhamnoides L.) fruit blend (SFB) containing sea buckthorn fruit extract, blueberry extract and collagen on UV-induced skin aging were examined by treating hairless mice for 6 weeks with UV irradiation and SFB administered orally. The effects of SFB were measured in the skin of these mice by phenotypical and histological analysis and western blotting. According to wrinkle formation analysis, the oral intake of SFB induced a decrease in wrinkle formation in the damaged skin of UV-irradiated mice. The thickness of the epidermis and dermis in the vitamin extracts (Vit)- and SFB-treated group was lower than that in the vehicle-treated group, but the group treated with SFB50 was the most effective group. The mice treated with the Vit- or SFB solution maintained a normal moisture content through the inhibition of transdermal water loss (TEWL) and an increase in skin moisture content. Furthermore, the levels of matrix metalloproteinase (MMP) and collagen protein expression were assessed in five groups to examine the mechanisms underlying the effects of SFB oral intake. The application of SFB induced a decrease in MMP-1 and -9 expression to the levels observed in the vehicle-treated group, but MMP-9 expression showed a much larger decrease than MMP-1. Furthermore, the expression of collagen-1 in the skin corresponded to MMP expression except for the SFB30-treated group, whereas the superoxide dismutase (SOD) activity was increased dramatically in the SFB50-treated group. These results suggest that SFB has potential as a protective and therapeutic drug candidate against skin aging that functions by regulating the moisture content, MMP expression levels and SOD activity.

show abstract

“…The oral administration of milk fermented with L. helveticus strain CM4 decreased transepidermal water loss and the size of dermatitis area in SDS-exposed Hos:HR-1 hairless mice, improving skin moisture content. On the contrary, no significant effects were exerted by artificially acidified milk whey (Baba et al, 2010). In vitro experiments on human epidermal keratinocytes supplemented with the same fermented milk whey preparation identified an increase in profilaggrin mRNA, a precursor of filaggrin that is involved in epidermal hydration and flexibility and is a marker of epidermal terminal differentiation (Baba et al, 2006).…”

Section: Other Proposed Health-promoting Properties Of L Helveticusmentioning

confidence: 99%

Health-Promoting Properties of Lactobacillus helveticus

Taverniti¹,

Guglielmetti²

2012

Front. Microbio.

100

View full text Add to dashboard Cite

Lactobacillus helveticus is an important industrial thermophilic starter that is predominantly employed in the fermentation of milk for the manufacture of several cheeses. In addition to its technological importance, a growing body of scientific evidence shows that strains belonging to the L. helveticus species have health-promoting properties. In this review, we synthesize the results of numerous primary literature papers concerning the ability of L. helveticus strains to positively influence human health. Several in vitro studies showed that L. helveticus possesses many common probiotic properties, such as the ability to survive gastrointestinal transit, adhere to epithelial cells, and antagonize pathogens. In vivo studies in murine models showed that L. helveticus could prevent gastrointestinal infections, enhance protection against pathogens, modulate host immune responses, and affect the composition of the intestinal microbiota. Interventional studies and clinical trials have also demonstrated a number of health-promoting properties of L. helveticus. Finally, several studies suggested that specific enzymatic activities of L. helveticus could indirectly benefit the human host by enhancing the bioavailability of nutrients, removing allergens and other undesired molecules from food, and producing bioactive peptides through the digestion of food proteins. In conclusion, this review demonstrates that in light of the scientific literature presented, L. helveticus can be included among the bacterial species that are generally considered to be probiotic.

show abstract

Oral Intake ofLactobacillus helveticus-Fermented Milk Whey Decreased Transepidermal Water Loss and Prevented the Onset of Sodium Dodecylsulfate-Induced Dermatitis in Mice

Cited by 33 publications

References 11 publications

Surfactant-induced Chronic Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis

Surfactant-induced Chronic Pruritus: Role of L-Histidine Decarboxylase Expression and Histamine Production in Epidermis

UV radiation-induced skin aging in hairless mice is effectively prevented by oral intake of sea buckthorn (Hippophae rhamnoides L.) fruit blend for 6 weeks through MMP suppression and increase of SOD activity

Health-Promoting Properties of Lactobacillus helveticus

Contact Info

Product

Resources

About