Oral Infection by Staphylococcus Aureus in Patients Affected by White Sponge Nevus: A Description of Two Cases Occurred in the Same Family

Abstract

Introduction. White Sponge Nevus (WSN) is a rare pathology with a pathogenesis on genetic basis, a benign course and a localization affecting the mucosal keratin.WSN is usually a symptomless pathology: when pain is present, some authors reported reduction of symptoms by taking penicillin or oral tetracycline rinses, suggesting that a bacterial overinfection could be at the base of possible painful symptoms.Case Report. We describe 2 patients affected by WSN, father and son: they presented two different oral diseases associated with an infection by Staphylococcus aureus. So, we have performed a careful oral hygiene to reduce infection in the oral cavity. In the following days we prescribed 2 rinses a day with a mouthwash containing chlorhexidine digluconate at two different percentages.Discussion. Early diagnosis of this lesion is important, because it allows us to exclude other more serious diseases. In the most part of cases, WSN requires no treatment because of its benign and asymptomatic behaviour: up to now, no protocol of treatment for this condition was standardized. Even if WSN is a painless condition, sometime a correlated painful symptomatology was reported.Conclusions. In our experience, we have achieved excellent results even with chlorhexidine digluconate rinses, considering that our treated cases were both infected by Staphylococcus aureus.We hypothesize that the corrugated plaques and the altered texture of the mucosa create the right conditions for the colonization and the development of microbial species such as saprophytic bacteria or fungal species.

Primary Diffuse Large B Cell Lymphoma Mimicking Hyperplastic Reactive Lesion (Lymphoma of the Oral Cavity)

“…Similarly to our case, another unusual case of gingival anaplastic large-cell lymphoma mimicking a benign hyperplastic lesion in a 57-year-old man as the first oral clinical manifestation of acquired immunodeficiency syndrome (AIDS) has been reported in the literature [10]. Other benignant oral lesions that might mimic potentially premalignant lesions, for instance, with sponge nevus, require careful clinical and histological examinations, avoiding misdiagnosis [17]. In face of the many potential diagnoses and considering the aggressive behavior of the lesion, the incisional biopsy was performed.…”

The Number of Platelets in Patient’s Blood Influences the Mechanical and Morphological Properties of PRP-Clot and Lysophosphatidic Acid Quantity in PRP

“…About bacterial infection of the oral cavity, it is scientifically confirmed that surface geometry and microarchitecture of materials modified eukaryotic cell adhesion [31] and cariogenic streptococci adhesion [32]. Moreover, the corrugated plaques together with the altered texture of the mucosa create the right conditions for the colonization and the development of microbial species such as saprophytic bacteria or fungal species [33]. The development of novel biomaterial coatings or scaffolds that enhance early osseointegration yet deters the attachment of bacteria are especially desirable properties to avoid aseptic and septic loosening.…”

Preterm Birth and Breastfeeding Are Related to Gastroesophageal Reflux Onset: An Observational Cross-Sectional Study

“…16,17 This anatomical and functional deficiency dramatically impair the PH level in preterm children oral cavity, affecting negatively the enamel structure and the efficacy of saliva to contrast common oral infections. 18 These salivary and PH alterations may be able to create an altered oral environment, leading to a development of atypically aggressive dental pathologies. 19 Our results confirmed the association between GER and preterm birth, as well as GER and breastfeeding: in the light of what literature have showed about the damages related to untreated GER in paediatric patients, we solicit a special attention when dentists perform the anamnesis and the first visit to factors as the long-time breastfeeding and the preterm birth.…”