Oral immunisation of wild boar against classical swine fever: evaluation of the first field study in Germany

Kaden, Volker; Lange, Elke; Fischer, Uwe; Strebelow, Günter

doi:10.1016/s0378-1135(00)00148-6

Cited by 105 publications

(153 citation statements)

References 5 publications

Supporting

Mentioning

144

Contrasting

Unclassified

Order By: Relevance

“…Field trials as well as the broad use of C-strain baits in Germany and France support the positive effect of vaccination on controlling CSF outbreaks in wild boar populations (Kaden, 1998, Kaden et al, 2001b, 2003, 2004a.…”

Section: Vaccinationmentioning

confidence: 92%

“…Other vaccine strains are the Japanese 22-140 GPE-negative strain, the Thiverval strain, and the Mexican PAV strains (EC, 2003;Blome et al, 2006). C-strain-based vaccines are also used for oral immunization of wild boar with vaccine carrying baits (Kaden et al, 2001a(Kaden et al, , 2001b(Kaden et al, , 2001c. In Germany, C-strain baits were used in several federal states like Mecklenburg-Western Pommerania, Rhineland Palatinate and North-Rhine-Westphalia (Kaden et al,2002(Kaden et al, , 2003(Kaden et al, , 2004a(Kaden et al, , 2005 During the development of marker vaccines it became clear that the E2-glycoprotein in a purified form was capable of inducing a protective immunity (Rümenapf et al, 1991;Van Zijl et al, 1991;Hulst et al, 1993;Konig et al, 1995;Van Rijn et al, 1996;Peeters et al, 1997).…”

Section: Types Of Vaccines For the Potential Use Of Emergency Vaccinamentioning

confidence: 99%

“…It was shown that after oral application, MLV are highly efficacious both in domestic pigs and wild boar (Kaden and Lange, 2001;Kaden et al, 2001a;Kaden et al, 2000a). (Biront and Leunen, 1988).…”

Section: Efficacymentioning

confidence: 99%

“…The vaccine used is attenuated C-strain in liquid form (Chenut et al,1999) and is incorporated into smelly baits that are attractive for wild boar (Kaden et al,2000a).…”

Section: Vaccinationmentioning

confidence: 99%

“…Baits are distributed either by hand or by airplane (Kaden et al, 2000a). Distribution by hand is performed by hunters on feeding grounds.…”

Section: Vaccinationmentioning

confidence: 99%

See 4 more Smart Citations

Control and eradication of Classic Swine Fever in wild boar

2009

EFSA Journal

View full text Add to dashboard Cite

SummaryClassical swine fever (CSF) is a disease that has been causing major socio-economic damages in the EU during the last decades. Although considerable progress has been made in the eradication and prevention of the disease, the threat for an epidemic still exists.The virus is endemic in the wild boar population of several member states (MS). Wild boar cannot be managed as domestic pigs. Hunting and vaccination have been tentatively used in order to stop transmission by reducing the number of susceptibles. Oral vaccination of wild boar with modified live vaccine based on the C-strain (the only suitable) is used; this vaccine does not allow serological differentiation between vaccinated and infected animals.The aim of the control measures for CSF in wild boar is to reduce the risk of transmission to domestic pigs, to prevent an "endemic phase evolution" or to reduce the endemic phase duration.In order to support and to improve the control and eradication measures as regards CSF in wild boar, EFSA was requested by the Commission to provide scientific advice on the efficacy of the available surveillance, hunting and vaccination measures to control and eradicate CSF in feral pig populations (wild boar), considering the possible use of new diagnostic tests and vaccines.In order to reply to the mandate data were collected from MS through two questionnaires (CSF vaccines, hunting practices and CSF vaccination in wild boar). Data were also extracted from the EU CSF wild boar data base, after requesting permission from the participating MS.Considering that the data received were rather limited and not comparable, the WG decided to use a model in order to fill the gaps in the available knowledge. For the evaluation of the efficacy of CSF control in wild boar a continuous metapopulation compartmental model developed in an EU research project (FP6-5015599-CSFVACCINE&WILDBOAR) was applied.Although the disease manifests in the same manner in both domestic pig and wild boar it is more difficult to identify in wild boar because clinical monitoring of these is hardly possible. Wild boar found dead constitutes the main alert sign of CSF. Hunters and gamekeepers should be instructed to report the finding of each dead wild boar to the competent authority at all times. In case of high-risk situations, a passive surveillance should be complemented by an active serological surveillance. The active sampling of wild boar is not as efficient as in domestic pigs considering that hunting is the sole practical system to obtain samples and that the aim of hunting is quite different.Consequently, the sample size is not controlled by authorities and fits rarely the aim of the survey in terms of detecting the presence of disease at a certain level. In addition, the interpretation of serological results is confounded by maternal derived antibodies (until the 6th month of age), vaccination and the sampling quality.There is no definition at EU level of spatial and temporal units for surveillance, neither for criteria defining a disease free wi...

show abstract

Section: Vaccinationmentioning

confidence: 92%

Section: Types Of Vaccines For the Potential Use Of Emergency Vaccinamentioning

confidence: 99%

Section: Efficacymentioning

confidence: 99%

“…The vaccine used is attenuated C-strain in liquid form (Chenut et al,1999) and is incorporated into smelly baits that are attractive for wild boar (Kaden et al,2000a).…”

Section: Vaccinationmentioning

confidence: 99%

“…Baits are distributed either by hand or by airplane (Kaden et al, 2000a). Distribution by hand is performed by hunters on feeding grounds.…”

Section: Vaccinationmentioning

confidence: 99%

See 3 more Smart Citations