Oral Candida carriage and prevalence of Candida species among Maras powder users and non‐users

Keten, Derya; Keten, Hamit Sırrı; Göktaş, Mustafa Tuğrul; Üçer, Hüseyin; Ersoy, Özgür; Çelık, Mustafa

doi:10.1111/jop.12260

Cited by 8 publications

(7 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…which are often reported at higher prevalence than C. dubliniensis [ 7 , 55 ], and among denture stomatitis patients, e.g. C. krusei and C. parapsilosis [ 56 , 61 ], or in oral samples in general, e.g. C. tropicalis [ 61 , 62 ], were not observed in this cohort.…”

Section: Resultsmentioning

confidence: 61%

See 1 more Smart Citation

Clonal evolution of Candida albicans, Candida glabrata and Candida dubliniensis at oral niche level in health and disease

Moorhouse

Moreno-Lopez

Gow

et al. 2021

Journal of Oral Microbiology

View full text Add to dashboard Cite

Background: Candida species have long been recognised as aetiological agents of opportunistic infections of the oral mucosa, and more recently, as players of polymicrobial interactions driving caries, periodontitis and oral carcinogenesis. Methods: We studied the clonal structure of Candida spp. at oral niche resolution in patients (n = 20) with a range of oral health profiles over 22 months. Colonies from oral micro-environments were examined with multilocus sequencing typing. Results: Candida spp. identified were C. albicans, C. glabrata and C. dubliniensis . Increased propensity for micro-variations giving rise to multiple diploid strain types (DST), as a result of loss of heterozygosity, was observed among C. albicans clade 1 isolates compared to other clades. Micro-variations among isolates were also observed in C. dubliniensis contra to expectations of stable population structures for this species. Multiple sequence types were retrieved from patients without clinical evidence of oral candidosis, while single sequence types were isolated from oral candidosis patients. Conclusion: This is the first study to describe the clonal population structure, persistence and stability of Candida spp. at oral niche level. Future research investigating links between Candida spp. clonality and oral disease should recognise the propensity to micro-variations amongst oral niches in C. albicans and C. dubliniensis identified here.

show abstract

Section: Resultsmentioning

confidence: 61%

“…C. krusei and C. parapsilosis [ 56 , 61 ], or in oral samples in general, e.g. C. tropicalis [ 61 , 62 ], were not observed in this cohort.…”

Section: Resultsmentioning

confidence: 68%

Clonal evolution of Candida albicans, Candida glabrata and Candida dubliniensis at oral niche level in health and disease

Moorhouse

Moreno-Lopez

Gow

et al. 2021

Journal of Oral Microbiology

View full text Add to dashboard Cite

show abstract

“…Many epidemiological studies have reported a close relationship between smoking and the occurrence of C. albicans infection. 2,3 A previous study reported that patients with clinically suspected oral leucoplakia (OLK) who had smoking habit were significantly associated with Candida infection. 4 We have previously shown that smoking exacerbates oral C. albicans infection and dampens the defence response of epithelial cells in rats.…”

Section: Introductionmentioning

confidence: 99%

Smoking increases oral mucosa susceptibility to Candida albicans infection via the Nrf2 pathway: In vitro and animal studies

Chen

Huang

et al. 2021

J Cellular Molecular Medi

View full text Add to dashboard Cite

Smoking and Candida albicans (C. albicans) infection are risk factors for many oral diseases. Several studies have reported a close relationship between smoking and the occurrence of C. albicans infection. However, the exact underlying mechanism of this relationship remains unclear. We established a rat infection model and a C. albicans‐Leuk1 epithelial cell co‐culture model with and without smoke exposure to investigate the mechanism by which smoking contributes to C. albicans infection. Oral mucosa samples from healthy individuals and patients with oral leucoplakia were also analysed according to their smoking status. Our results indicated that smoking induced oxidative stress and redox dysfunction in the oral mucosa. Smoking‐induced Nrf2 negatively regulated the NLRP3 inflammasome, impaired the oral mucosal defence response and increased the oral mucosa susceptibility to C. albicans. The results suggest that the Nrf2 pathway could be involved in the pathogenesis of oral diseases by mediating an antioxidative response to cigarette smoke exposure and suppressing host immunity against C. albicans.

show abstract

“…Some studies have reported that the carriage rate of oral Candida species in healthy subjects ranges between 17% and 75% (2,3). A significant risk factor for increased oral Candida carriage is habitual tobacco usage (cigarette smoking and tobacco chewing) (4,5). One possible reason for this is that chemicals in tobacco, such as nicotine, nitrosodietheinal amine and aromatic hydrocarbons, act as sources of nutrition for Candida species, thus facilitating their growth (6).…”

Section: Introductionmentioning

confidence: 99%

Comparison of oral Candida carriage in waterpipe smokers, cigarette smokers, and non-smokers

Akram

Al‐Kheraif

Kellesarian

et al. 2018

Journal of Oral Science

View full text Add to dashboard Cite

The aim of the present cohort study was to compare oral carriage of Candida in waterpipe smokers (WS), cigarette smokers (CS), and non-smokers (NS). A total of 141 individuals (46 WS, 45 CS, and 50 NS) were included. A questionnaire was used to gather demographic information and data on the daily frequency and duration of smoking habits, the reasons for smoking, and daily oral hygiene maintenance habits. Oral Candida (C.) samples were cultured and yeast species were identified using polymerase chain reaction. Unstimulated whole salivary flow rate (UWSFR) was also recorded. The numbers of missing teeth (MT) were counted and tongue lesions were clinically identified. C. albicans was the most prevalent yeast species isolated from all groups. Oral C. albicans carriage was higher among WS (P < 0.05) and CS (P < 0.05) than among NS. Oral C. tropicalis carriage, age, UWSFR and the number of MT were comparable among the groups. Oral Candida carriage was significantly higher among WS and CS than among NS. Therefore it appears that WS and CS are at an increased risk of developing oral candida infections.

show abstract

Oral Candida carriage and prevalence of Candida species among Maras powder users and non‐users

Cited by 8 publications

References 28 publications

Clonal evolution of Candida albicans, Candida glabrata and Candida dubliniensis at oral niche level in health and disease

Clonal evolution of Candida albicans, Candida glabrata and Candida dubliniensis at oral niche level in health and disease

Smoking increases oral mucosa susceptibility to Candida albicans infection via the Nrf2 pathway: In vitro and animal studies

Comparison of oral <i>Candida</i> carriage in waterpipe smokers, cigarette smokers, and non-smokers

Contact Info

Product

Resources

About