Oral health management of a patient with 47,XYY syndrome

Shah, Altaf; Manjunatha, Bhari Sharanesha; Bindayel, Naif A; Khounganian, Rita

doi:10.1136/bcr-2013-010408

Cited by 3 publications

(2 citation statements)

References 18 publications

(20 reference statements)

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“…Narrow forehead [53], brachycephaly [56], dental anomalies (such as delayed eruption, ectopic teeth, hypodontia, enamel defects) [49] Tibiofibular synostosis [50], unilateral preaxial hexadactyly [49], hip dysplasia [49,55], bilateral clubfoot [69], pes valgus [49] Mosaicism (47,XXY/46,XX) − − Jacobs syndrome 47,XYY Delayed eruption of permanent teeth [57,61], bimaxillary protrusion [61], enlarged head circumference [61], facial asymmetry [61], macrodontia [13], agenesia of permanent maxillary lateral incisors [13] Short hands [62], radial head dislocation [71], cubitus varus [71], hindfoot varus [71], pes cavus [71] Mosaicism − −…”

Section: Xxxxymentioning

confidence: 99%

Skeletal and dental abnormalities in patients with sex chromosome aberrations: a systematic case-based review

Gruszczyński¹,

Nijakowski²,

Wolska-Bułach³

et al. 2022

polp

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Sex chromosome aneuploidies (SCAs) are common chromosomal disorders characterised by an atypical number of sex chromosomes. Turner syndrome (TS), Klinefelter syndrome (KS), and Jacobs syndrome (JS) are associated with a wide spectrum of skeletal manifestations, including craniofacial and limb anomalies. This systematic review aimed to analyse the incidence of skeletal abnormalities in selected SCAs based on case reports. In this review, 55 articles were included from the MEDLINE/PubMed and Google Scholar databases, according to PRISMA guidelines. High-arched palate, skeletal class II, and cubitus valgus were most frequently demonstrated among TS patients. Patients with KS and JS most often presented micrognathia, hypertelorism, and flat nasal bridge in the craniofacial region. In contrast, radioulnar synostosis, clinodactyly, and pes planus could be observed in the limbs of KS patients. The presence of dysmorphic facial features and limb malformations may indicate SCAs, which are underdiagnosed in the general population due to a variety of phenotypes.

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Section: Xxxxymentioning

confidence: 99%

Skeletal and dental abnormalities in patients with sex chromosome aberrations: a systematic case-based review

Gruszczyński¹,

Nijakowski²,

Wolska-Bułach³

et al. 2022

polp

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show abstract

“…Results also showed that the FISH, Cbanding and quantitative fluorescent PCR is a fast and reliable method for detection of additional Y chromosome aneuploidies. In general, the majority of XYY males are phenotypically, normal but limited literature findings claimed the possible role of double Y chromosomes and autism [10][11][12][13] . The current case of 47,XYY syndrome was reported due to without autistic profiles such as language and social impairment.…”

Section: Case Reportmentioning

confidence: 99%

An infertile case of 47,XYY syndrome without autistic spectrum: Cost effective well-define of extra Y chromosome by GTG, C bandings, QF-PCR and FISH analyses

Özdemir

Paksoy

Gurgen

et al. 2016

Cumhuriyet Medical Journal

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The Autism Spectrum Disorders (ASD) was frequently reported in autosomal and sex chromosome abnormalities and limited findings pointed out the Y chromosome. In the current case, it was aimed to identify the genetic cause for a man without autism profiles using combined cytogenetic and molecular genetic techniques. Automated karyotype analysis was made after combined methods with GTG, C bandings, QF-PCR and FISH techniquesfor the current case. Additional Y chromosome was identified after conventional GTG and C-banded karyotype analysis. The current case of 47,XYY syndrome was reported due to without autistic profiles such as language and social impairment. The proband's karyotype was determined as 47,XYY. No other numerical and/or structural chromosomal abnormalities were detected in the karyotype analysis. Cytogenetic methods combined with cost-effective techniques such as C, GTG banding and FISH provide well-define of extra Y chromosome in the presented case of without autistic spectrum. Both Y chromosomes were in the same size and C-banded profiles in the current proband pointed out that both are originated from one chromosome by endoreduplication Y chromosome after zigot formation

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Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome

Scheidt¹,

Sanabe²,

Diniz³

2015

J Indian Soc Pedod Prev Dent

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Chromosome 47, XYY syndrome is usually diagnosed late. Some of the clinical characteristics of XYY syndrome may be perceptible in dental care. The slow development of cognitive and motor activities and tall stature is common in XYY patients. The aim of this article was to relate the oral, physical, and behavioral aspects of a 6-year-old patient with the chromosome 47, XYY syndrome, diagnosed by means of karyotyping. The patient presented motor difficulty, which led to a fall and traumatism in the anterior region. In the radiography, agenesia of the permanent maxillary lateral incisors, presence of taurodontism in the primary molars, and macrodontia of the maxillary central incisors and permanent molars could be observed. Once the diagnosis was made, it was possible to understand his difficulty at school, and make available appropriate monitoring by a suitable multidisciplinary team to stimulate, control, and minimize the day-to-day difficulties found by patients with this syndrome.

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Oral health management of a patient with 47,XYY syndrome

Cited by 3 publications

References 18 publications

Skeletal and dental abnormalities in patients with sex chromosome aberrations: a systematic case-based review

Skeletal and dental abnormalities in patients with sex chromosome aberrations: a systematic case-based review

An infertile case of 47,XYY syndrome without autistic spectrum: Cost effective well-define of extra Y chromosome by GTG, C bandings, QF-PCR and FISH analyses

Oral, physical, and behavioral aspects of patient with chromosome 47, XYY syndrome

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