Oral furosemide and hydrochlorothiazide/amiloride versus intravenous furosemide for the treatment of nephrotic edema

Optimizing diuretic treatment of patients with edema and nephrotic syndrome

“…In pediatric patients, amiloride was as effective as furosemide and additive. 5 In adult patients with NS, amiloride (or its analogue triamterene) has been administered as a rational add-on for sequential blockade of Na + transporters along the nephron 6,7 or as add-on in single patients with NS and resistant edema with remarkable, but casuistic, effect. 8 Schork et al show in adult patients with NS 1 that amiloride significantly reduced OH on Day 8, and both drugs did at Day 16 compared to baseline.…”