Oral fibrous histiocytoma and its angiomatoid variant

Benign Fibrous Histiocytoma of Larynx: A Rare Case Report

“…The benign fibrous histiocytoma (BFH) or fibrohistiocytoma is one of the most common mesenchymal tumors in adults, which is usually found to be of cutaneous origin and its presence in non-cutaneous deep organs of the body is rare with few reports in literature [4].…”

Benign Fibrous Histiocytomas of the Oral Mucosa: Report on Three Cases and Review of the Literature

“…Although these lesions do not produce any repercussion on the patients’ general health, they may have local consequences, for example interfere with mastication and compress or displace anatomical structures. Rarely, multiple BFH may occur due to immunosuppression [ 2 ], but none of the oral BHF reviewed had presented as multiple lesions [ 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ]. The overlying mucosa remains most often intact but can show periods of ulceration [ 4 ] due to traumatism, in which case lesions may become painful.…”

“…Fibrous histiocytoma has a malignant form, which is more often encountered in the literature. An intermediately aggressive variant (angiomatoid variant) has also been recognized since 1995 [ 27 ] and is described as having a local aggressiveness and a low rate of metastasis [ 27 , 12 ].…”

“…Only rarely lesions may involve the oral mucosa or jaw bones [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ]. In the oral mucosa, BFH show a predilection to the buccal mucosa and vestibule [ 1 , 4 , 5 , 6 , 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 ]. Compared to oral mucosal lesions, intraosseous lesions that involve the jaw bones are extremely uncommon, with 7 cases of mandibular and 2 maxillary BFH reported to date [ 3 ].…”

Oral Benign Fibrous Histiocytoma – A Review of Literature from 1964-2016

“…CT scans can be of diagnostic aid in Fibrohistiocytic tumours of the bone which presents as a well defined, expansile lytic lesion may or may not be associated with thinning or breach in the cortical plates.MRI scans are used in case of Fibrohistiocytic tumours of the soft tissues which show up as heterogeneously hyper intense on T2-weighted image [14][15][16]. Role of PET scans is not much tapped into and may pave way for better imaging in the recent future.…”