Oral exfoliative cytology and corrosion of metal piercings. Tissue implications

Abstract

We propose the use of exfoliative cytology to monitor corrosion processes and for routine clinical follow up.

Peri‐implantitis is not periodontitis: Scientific discoveries shed light on microbiome‐biomaterial interactions that may determine disease phenotype

“…These findings support a strong role of titanium dissolution products in peri‐implantitis, which may indirectly result in a shift of the peri‐implant microbiome toward dysbiosis. In corroboration, recent studies focusing on potential causative factors of peri‐implantitis have consistently pointed to titanium particles as being associated with peri‐implant inflammation 33,35,76,77 …”

“…In corroboration, recent studies focusing on potential causative factors of peri-implantitis have consistently pointed to titanium particles as being associated with peri-implant inflammation. 33,35,76,77…”

The impact of piercing on various aspects of oral health

“…It should be remembered that exposure to metal ions and particles, which are components of intra-oral jewelry, contributes to the development of hypersensitivity reactions and contact allergy, on the basis of which lichen planus may develop. Lichen planus, on the other hand, poses a risk of developing squamous cell carcinoma of the oral cavity [3,5]. A very rare local complication of oral piercing infection may also be Ludwig's angina, which is an inflammation of the connective tissue of the floor of the mouth and neck, and is potentially life-threatening [14,15].…”

“…hepatitis, HIV, tetanus, tuberculosis), and as a cause of bacterial endocarditis in susceptible patients [1,3,4]. The AAPD strongly opposes the practice of intraoral and perioral tissue piercing and the use of jewelry on intraoral and perioral tissues because of the potential for pathological conditions and after-effects associated with these practices [1,5,6]. Such strong reactions and recommendations of Polish specialists, however, are missing in the national literature.…”

A decennary update on applications of metal nanoparticles (MNPs) in the synthesis of nitrogen- and oxygen-containing heterocyclic scaffolds

“…3 A recent analysis on structures of USFDAapproved drugs administered in combination with other drugs as reported by Njardarson et al revealed that the major importance of these heterocycles in combination drugs is in variety of therapeutic uses. 4 The rich literature [5][6][7][8][9][10][11][12][13][14] on the synthesis of these USFDA-approved drugs is also gaining momentum since for the clinical use of a drug, the drug molecule has be synthesized on a pilot scale using a suitable toolbox of organic chemistry. 15 A plot of the number of publications versus year of publication performed using Sci-Finder 16 for the search string 'synthesis of heterocyclic scaffolds' revealed the increasing popularity of heterocyclic scaffolds synthesized via several organic transformations (Fig.…”