Oral erythema multiforme related to bronchodilators intake: A report of a case

Abstract

Erythema multiforme is a reactive inflammatory mucocutaneous disorder. It is classified into three groups: erythema multiforme minor, major, and oral erythema multiforme. The oral mucosa is mostly involved. The etiology of this lesion varied from bacterial, viral, or fungal infection to drug reaction. The aim was to report a case of oral erythema multiforme related to drug intake, in order to highlight clinical and histological features in addition to therapeutic modalities of drug‐induced oral erythema multiforme. A 74‐year‐old female patient consulted for painful ulcerations in the oral cavity, associated with burning sensation and inability to eat or swallow for the past 8 days. After detailed anamnesis and clinical examination, the diagnosis of oral erythema multiforme related to drug intake was retained. Oral erythema multiforme is a benign inflammatory disorder involving the oral mucosa with pathognomonic clinical and histological features. It may result from viral, bacterial, or fungal infection and from drug intake reaction. The interruption of the implicated molecule associated with symptomatic treatment is the principal therapeutic modalities.

Ibuprofen-Induced Pancytopenia and Erythema Multiforme in an Elderly Female Patient

“…The reported prevalence rate of EM is less than 1% [13]. EM typically occurs in young adults 20 to 40 years of age and is more common in women [13].…”

“…The reported prevalence rate of EM is less than 1% [13]. EM typically occurs in young adults 20 to 40 years of age and is more common in women [13]. Patients who are immunocompromised, immunosuppressed, or have underlying autoimmune disorders are more predisposed to developing EM [13].…”

“…EM typically occurs in young adults 20 to 40 years of age and is more common in women [13]. Patients who are immunocompromised, immunosuppressed, or have underlying autoimmune disorders are more predisposed to developing EM [13]. Although EM due to drugs is rare, the drugs that are most commonly associated are NSAIDs and antibiotics.…”