Oral disorders in patients with newly diagnosed haematological diseases

Uutela, Pauliina; Passweg, Jakob; Joda, Tim; Weiger, Roland; Mauramo, Matti; Waltimo, Tuomas

doi:10.1007/s00784-019-03178-3

Cited by 4 publications

(3 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Dental diseases were prevalent in this cohort, which is in accordance with other studies in recent years [ 17 , 18 , 30 , 36 – 38 ]. In our study, the overall incidence of periodontal diseases, measured clinically as PD >5 mm and BoP, was observed in almost 30% and 75% of patients, respectively.…”

Section: Discussionsupporting

confidence: 93%

Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study

et al. 2023

View full text Add to dashboard Cite

Despite advances in transplant medicine, prevalence of complications after hematopoietic stem cell transplantation (HSCT) remains high. The impact of pre-HSCT oral health factors on the incidence and severity of complications post-HSCT is poorly understood. The aim of this prospective, observational study was to analyze oral health in patients planned for HSCT. Patients ≥18 years requiring HSCT were included from five sites between 2011–2018. General health, oral findings and patient-reported symptoms were registered in 272 patients. Oral symptoms around disease onset were reported by 43 patients (15.9%) and 153 patients (58.8%) reported oral complications during previous chemotherapy. One third of patients experienced oral symptoms at the oral examination before conditioning regimen and HSCT. In total, 124 (46.1%) patients had dental caries, 63 (29.0%) had ≥one tooth with deep periodontal pockets, 147 (75.0%) had ≥one tooth with bleeding on probing. Apical periodontitis was observed in almost 1/4 and partially impacted teeth in 17 (6.3%) patients. Oral mucosal lesions were observed in 84 patients (30.9%). A total of 45 (17.4%) of 259 patients had at least one acute issue to be managed prior to HSCT. In conclusion, oral symptoms and manifestations of oral disease were prevalent in patients planned for HSCT. The extent of oral and acute dental diseases calls for general oral screening of patients pre-HSCT.

show abstract

Section: Discussionsupporting

confidence: 93%

Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study

et al. 2023

View full text Add to dashboard Cite

show abstract

“…These results reinforce the need for developing oral hygiene protocols and the inclusion of dental professionals in the hospital team, both to provide proper care to patients who are dependent on medical figures, and as a preventative measure for all independent patients, to whom dental professionals could offer instruction on correct oral hygiene methods. In fact, including oral health care programs is effective in the prevention of pneumonia [ 10 ], reducing the pain of oral mucositis in patients undergoing chemotherapy [ 29 ], allowing early detection of caries in patients with severe hematologic pathologies (which could aggravate the risk of atherosclerosis) [ 30 ], facilitating the screening of patients with diabetes for the prevention of inflammation [ 31 ], and reducing the risk of developing cardiovascular disease [ 32 ]. In addition, hospitalized patients may be directly or indirectly exposed to factors that may impair their oral health status, and the difficulty of maintaining proper oral hygiene during hospitalization worsens this risk [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Oral Hygiene Practice among Hospitalized Patients: An Assessment by Dental Hygiene Students

et al. 2022

View full text Add to dashboard Cite

Aim: An epidemiological study was carried out, in hospital wards, with the aim of assessing the oral health status of patients subjected to multiple medical treatments. Material and Methods: The study was conducted at Fondazione IRCCS Policlinico San Matteo (Pavia, Italy). A questionnaire was submitted to patients for the evaluation of oral hygiene devices used; then, a clinical examination was conducted to collect Decayed Missing Filled Teeth (DMFT) index, Plaque Index (PI), and Marginal Gingival Index (MGI) values. Results: Manual toothbrushes were used by a wide range of the sample study (65–100% among hospital wards), together with mouthwash (20–80%); interproximal aids were used by few patients (the lowest recorded value was 33.3%). Conclusion: dental hygienists could be integrated into hospital wards as oral hygiene procedure instructors, for the improvement of the oral health conditions of hospitalized patients.

show abstract

“…The interaction between leukemia and the oral microbiome exacerbates periodontal disease. The infiltration of leukemic cells into the gingiva, combined with an impaired immune response, creates conditions for the destruction of the periodontium and complicates the maintenance of oral hygiene, increasing the risk of infection [ 105 , 106 ].…”

Section: The Relationship Between Hematological Disorders and Periodo...mentioning

confidence: 99%

The Bloody Crossroads: Interactions between Periodontitis and Hematologic Diseases

Łobacz,

Mertowska,

Mertowski

et al. 2024

IJMS

View full text Add to dashboard Cite

Periodontitis is a common oral condition that can have a significant impact on the overall health of the body. In recent years, attention has been paid to potential relationships between periodontitis and various hematological disorders. This publication aims to present information available in the literature on this relationship, focusing on examples of red blood cell disorders (such as aplastic anemia and sickle cell anemia) and white blood cell disorders (such as cyclic neutropenia, maladaptive trained immunity, clonal hematopoiesis, leukemia, and multiple myeloma). Understanding these associations can help physicians and dentists better diagnose, monitor, and treat patients associated with both groups of conditions, highlighting the need for interdisciplinary care for patients with oral disorders and hematologic diseases.

show abstract

Oral disorders in patients with newly diagnosed haematological diseases

Cited by 4 publications

References 38 publications

Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study

Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study

Oral Hygiene Practice among Hospitalized Patients: An Assessment by Dental Hygiene Students

The Bloody Crossroads: Interactions between Periodontitis and Hematologic Diseases

Contact Info

Product

Resources

About