Oral cryotherapy reduces mucositis and improves nutrition – a randomised controlled trial

Svanberg, Anncarin; Öhrn, Kerstin; Birgegård, Gunnar

doi:10.1111/j.1365-2702.2010.03255.x

Cited by 52 publications

(88 citation statements)

References 18 publications

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“…110 Surprisingly, mucositis severity does not correlate with incidence of BSI. For example, prospective studies evaluating interventions that are effective in reducing mucositis like keratinocyte growth factor 111 and cryotherapy 112 have not shown a beneficial effect in reducing BSI rates.…”

Section: Bloodstream Infection Preventionmentioning

confidence: 99%

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Dandoy

Ardura

Papanicolaou

et al. 2017

Bone Marrow Transplant

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Bacterial bloodstream infections (BSI) cause significant transplant-related morbidity and mortality following allogeneic hematopoietic cell transplantation (allo-HCT). This manuscript reviews the risk factors for and the bacterial pathogens causing BSIs in allo-HCT recipients in the contemporary transplant period. In addition, it offers insight into emerging resistant pathogens and reviews clinical management considerations to treat and strategies to prevent BSIs in allo-HCT patients.

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Section: Bloodstream Infection Preventionmentioning

confidence: 99%

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Dandoy

Ardura

Papanicolaou

et al. 2017

Bone Marrow Transplant

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“…[1][2][3] OM is a significant posttransplant complication, and together with gut tissue damage and inflammation, caused by conditioning regimens, contributes to the development and pathogenesis of acute GVHD. [4][5][6] The incidence of acute GVHD varies between 28 and 45% in the Flu/Mel-reduced intensity conditioning regimen comprising of fludarabine total dose 125-150 mg/m 2 and melphalan total dose 140-180 mg/m 2 .…”

mentioning

confidence: 99%

Oral cryotherapy can significantly reduce oral mucositis but not acute GVHD incidence in Flu/Mel conditioning allo-SCT

Vokurka

Svoboda

Jungová

et al. 2011

Bone Marrow Transplant

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influenced the detailed results of our analysis: more peripheral SC grafts and lower MTX dose administered in the non-cryotherapy group, fewer sibling donor transplantations in cryotherapy group, some patients lost from observation for mortality reasons before day þ 100 without developing acute GVHD. We assume, however, that our findings are potent enough to state, that even although oral cryotherapy significantly reduced OM, it had no impact on acute GVHD incidence reduction. Our findings do not exclude OM from the acute GVHD pathogenesis, but its role appears less significant compared with other possible factors. To get more precise results, a large study comparing the extent of gut damage, OM and acute GVHD characteristics would be needed.

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“…[26] Araştırmalarda oral kriyoterapi buz küplerinin ağızda bekletilmesi ya da soğuk su ile ağız çalkalanması yöntemi ile uygulanmıştır.…”

Section: Kriyoterapiunclassified

Complementary Therapies in the Management of Induced Oral Mucositis during Cancer Treatment

İzgü¹

2017

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ÖZKanser tedavisine bağlı gelişen oral mukozit; ağrı, beslenmede yetersizlik, kilo kaybı ve tedavinin ertelenmesi gibi birçok soruna yol açan ve hastaların yaşam kalitesini olumsuz yönde etkileyen önemli bir sorundur. Mevcut ağız bakımı yaklaşımlarına rağmen bu sorun güncelliğini korumakta ve yeni yöntemlerin etkinliği araştırılmaktadır. Etkinliği araştırılan uygulamalar arasında tamamlayıcı tedaviler, sağlık profesyonellerinin oral mukozit yönetimine ilişkin kanıt oluşturmak amacıyla sıklıkla araştırma yaptığı alanlardan biri haline gelmiştir. Kriyoterapi, düşük yoğunluklu lazer tedavisi, bitkisel yaklaşımlar ve besin destekleri, apiterapi, esansiyel yağlar ve bilişsel davranışçı yaklaşımlar oral mukozit yönetiminde etkinliği araştırılan tamamlayıcı tedavi yaklaşım-ları arasında yer almaktadır. Bu derlemede kanser tedavisine bağlı gelişen oral mukozit yönetiminde etkinliği araştırılmış tamamlayıcı tedavi yaklaşımlarına ilişkin araştırma örnekleri sunulmuş ve bu yöntemlerle ilgili kanıta dayalı uygulama rehberlerinde yer alan önerilere yer verilmiştir.

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Oral cryotherapy reduces mucositis and improves nutrition – a randomised controlled trial

Abstract: Nurses caring for patients treated with myeloablative therapy should place high priority to prevent oral mucositis and hereby reduce its side effects.

Cited by 52 publications

References 18 publications

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Bacterial bloodstream infections in the allogeneic hematopoietic cell transplant patient: new considerations for a persistent nemesis

Oral cryotherapy can significantly reduce oral mucositis but not acute GVHD incidence in Flu/Mel conditioning allo-SCT

Complementary Therapies in the Management of Induced Oral Mucositis during Cancer Treatment

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