Oral collagen supplementation for skin aging: A fad or the future?

Jhawar, Nikita; Wang, Jordan V; Saedi, Nazanin

doi:10.1111/jocd.13096

Cited by 35 publications

(31 citation statements)

References 14 publications

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“…In recent years, oral collagen supplementation has become popular as it has been increasingly marketed to consumers as an anti-aging product, because HC oral supplementation reaches the deeper layers of the skin and improves skin physiology and appearance increasing hydration, elasticity, firmness, wrinkle reduction, and skin rejuvenation [122,123] (Table 2).…”

Section: Hydrolyzed Collagen: Sources and Applicationsmentioning

confidence: 99%

Hydrolyzed Collagen—Sources and Applications

et al. 2019

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Hydrolyzed collagen (HC) is a group of peptides with low molecular weight (3–6 KDa) that can be obtained by enzymatic action in acid or alkaline media at a specific incubation temperature. HC can be extracted from different sources such as bovine or porcine. These sources have presented health limitations in the last years. Recently research has shown good properties of the HC found in skin, scale, and bones from marine sources. Type and source of extraction are the main factors that affect HC properties, such as molecular weight of the peptide chain, solubility, and functional activity. HC is widely used in several industries including food, pharmaceutical, cosmetic, biomedical, and leather industries. The present review presents the different types of HC, sources of extraction, and their applications as a biomaterial.

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Section: Hydrolyzed Collagen: Sources and Applicationsmentioning

confidence: 99%

Hydrolyzed Collagen—Sources and Applications

et al. 2019

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“…Aesthetic‐based manufacturers have taken advantage of this consumer interest by developing and marketing various over‐the‐counter treatments, including oral supplements. Recently, oral collagen peptides have been advertised to reverse the clinical signs of aging by increasing dermal collagen, hyaluronic acid, and water content of the skin 2‐4 . Although there are many purported benefits of ingesting collagen peptides, few studies have actually validated their efficacy, and larger, more robust studies are still needed.…”

Section: Figurementioning

confidence: 99%

“…Recently, oral collagen peptides have been advertised to reverse the clinical signs of aging by increasing dermal collagen, hyaluronic acid, and water content of the skin. [2][3][4] Although there are many purported benefits of ingesting collagen peptides, few studies have actually validated their efficacy, and larger, more robust studies are still needed. Currently, the available evidence remains limited, contradictory, and lacking in standardized methodology; 3,4 despite this, the popularity of oral collagen supplements continues to rise.…”

mentioning

confidence: 99%

“…[2][3][4] Although there are many purported benefits of ingesting collagen peptides, few studies have actually validated their efficacy, and larger, more robust studies are still needed. Currently, the available evidence remains limited, contradictory, and lacking in standardized methodology; 3,4 despite this, the popularity of oral collagen supplements continues to rise. A more in depth understanding of this trend may offer practitioners insights into consumer perspectives and expectations, which can help guide patient education and counseling.…”

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confidence: 99%

“…Consequently, it is important to understand the proposed molecular pathways at play. These collagen supplements are theorized to increase hyaluronic acid production by skin fibroblasts, induce the migration of fibroblasts, promote stronger collagen fibrils, and increase water content of the stratum corneum by increasing the total availability of biologically active peptides in the skin [2][3][4]. Animal studies have reported encouraging data, but clinically translating these results to humans may be limited by differences in physiology and pharmacokinetics 3.…”

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confidence: 99%

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Understanding aesthetic interest in oral collagen peptides: A 5‐year national assessment

Albornoz

Shah

Murgia

et al. 2020

J of Cosmetic Dermatology

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Oral supplementation with collagen peptides has recently grown in popularity. It has been marketed to offer skin rejuvenating properties, such as wrinkle reduction, skin plumping, and moisturizing effects. However, current data are limited regarding its effects on the skin. Despite the controversial status of oral collagen supplements, its popularity has continued to rise. Here, we examine the consumer interest in oral collagen peptides over a 5‐year period in the United States.

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Skincare potential of a sustainable postbiotic extract produced through sugarcane straw fermentation by Saccharomyces cerevisiae

Duarte

Carvalho

et al. 2023

BioFactors

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Postbiotics are defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit on the host.” They can be produced by fermentation, using culture media with glucose (carbon source), and lactic acid bacteria of the genus Lactobacillus, and/or yeast, mainly Saccharomyces cerevisiae as fermentative microorganisms. Postbiotics comprise different metabolites, and have important biological properties (antioxidant, anti‐inflammatory, etc.), thus their cosmetic application should be considered. During this work, the postbiotics production was carried out by fermentation with sugarcane straw, as a source of carbon and phenolic compounds, and as a sustainable process to obtain bioactive extracts. For the production of postbiotics, a saccharification process was carried out with cellulase at 55°C for 24 h. Fermentation was performed sequentially after saccharification at 30°C, for 72 h, using S. cerevisiae. The cells‐free extract was characterized regarding its composition, antioxidant activity, and skincare potential. Its use was safe at concentrations below ~20 mg mL−1 (extract's dry weight in deionized water) for keratinocytes and ~ 7.5 mg mL−1 for fibroblasts. It showed antioxidant activity, with ABTS IC50 of 1.88 mg mL−1, and inhibited elastase and tyrosinase activities by 83.4% and 42.4%, respectively, at the maximum concentration tested (20 mg mL−1). In addition, it promoted the production of cytokeratin 14, and demonstrated anti‐inflammatory activity at a concentration of 10 mg mL−1. In the skin microbiota of human volunteers, the extract inhibited Cutibacterium acnes and the Malassezia genus. Shortly, postbiotics were successfully produced using sugarcane straw, and showed bioactive properties that potentiate their use in cosmetic/skincare products.

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Oral collagen supplementation for skin aging: A fad or the future?

Cited by 35 publications

References 14 publications

Hydrolyzed Collagen—Sources and Applications

Hydrolyzed Collagen—Sources and Applications

Understanding aesthetic interest in oral collagen peptides: A 5‐year national assessment

Skincare potential of a sustainable postbiotic extract produced through sugarcane straw fermentation by Saccharomyces cerevisiae

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