Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation

Bray, Jonathan JH; Warraich, Mazhar; Whitfield, Michael G.; Peter, Christina; Baral, Ranu; Ahmad, Mahmud; Ahmad, Shazaib; Abraham, George; Kirresh, Ali; Sahibzada, Muhammad Salman; Muzaffar, Adnan; Tomson, Joseph; Lambiase, Pier D.; Captur, Gabriella; Banerjee, Amitava; Providência, Rui

doi:10.1002/14651858.cd013765.pub2

Cited by 3 publications

(2 citation statements)

References 69 publications

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“…[14][15][16] In numerous studies, the use of Cordarone (amiodarone) for 3 months following surgical ablation of AF has shown a significant reduction in AF recurrence. 17,18 In our practice, patients were prescribed Cordarone for up to 3 months after surgery, with discontinuation occurring in case of drugrelated complications or after the 3-month period. This approach has contributed to maintaining a 5-year followup rate, with nearly 60% of patients remaining free from AF.…”

Section: Discussionmentioning

confidence: 99%

Concomitant Surgical Ablation for Treatment of Atrial Fibrillation in Patients Undergoing Minimally Invasive Mitral Valve Surgery: A Single-Center Experience in Vietnam

Chuong,

Thuan,

Thanh

et al. 2024

Thorac Cardiovasc Surg

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Background This study presents the early and midterm outcomes of combining atrial fibrillation (AF) treatment with minimally invasive mitral valve surgery (MIMVS) at our center. Methods From January 2017 to June 2022, our center treated a total of 86 patients with both MIMVS and surgical AF ablation. The patient cohort included 62 women (72.1%) and 24 men (27.9%). The average EuroScore II was 2.64 ± 1.49%, and the patients were followed up for an average period of 46.31 ± 9.84 months. Results Postoperatively, 95.3% of patients experienced a change in sinus rhythm, and 86.2% were discharged in sinus rhythm. The hospital's mortality rate was 2.3%, with a late mortality rate of 3.5%. Survival analysis revealed an atrial fibrillation–free 5-year follow-up rate of 59.1 ± 9.1%. The 5-year survival rate was 92.7 ± 3.3%. Conclusion Our 5-year experience demonstrates that the combination of MIMVS and surgical AF ablation can be routinely performed with favorable peri- and postoperative outcomes. This reflects our hospital's culture and guidance on patient selection, particularly when adopting minimally invasive approaches for multiple procedures.

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Section: Discussionmentioning

confidence: 99%

Concomitant Surgical Ablation for Treatment of Atrial Fibrillation in Patients Undergoing Minimally Invasive Mitral Valve Surgery: A Single-Center Experience in Vietnam

Chuong,

Thuan,

Thanh

et al. 2024

Thorac Cardiovasc Surg

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“…This is because it can significantly impact left atrial (LA) anatomical and electrical remodeling, ultimately reducing the risk of AA recurrence ( 13 ). Given the availability of various AAD, different treatment regimens may lead to different outcomes ( 14 ).…”

Section: Introductionmentioning

confidence: 99%

Factors influencing early recurrence of atrial fibrillation among elderly patients following radiofrequency catheter ablation and the impact of different antiarrhythmic regimens

Fei,

Zhao,

et al. 2024

Front. Med.

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BackgroundPatients with atrial fibrillation (AF) who undergo radiofrequency catheter ablation (RFCA) necessitate the administration of antiarrhythmic drugs to prevent early recurrence. The clinical outcomes among these patients may be influenced by varying antiarrhythmic regimens.ObjectivesTo identify the risk factors associated with early recurrence and compare the clinical outcomes among different antiarrhythmic regimens in elderly patients with AF following radiofrequency catheter ablation (RFCA) during a 3-month period.MethodsA retrospective observational study encompassed 420 elderly patients with AF following RFCA. Baseline data were collected during the initial postoperative visit and clinical outcomes were carefully monitored over a 3-month follow-up period. Logistic regression and Cox-proportional hazard regression analyses were performed to investigate the relationship between various antiarrhythmic regimens and the clinical outcomes.ResultsMultivariate logistic regression analysis revealed that age (p = 0.001), left atrial diameter (p < 0.001), left ventricular diameter (p = 0.015), reactive hyperemia index (RHI) (p < 0.001), antiarrhythmic drug (p < 0.001) and hs-cTnI (p = 0.017) were independent risk factors of early recurrence. Furthermore, in cox survival regression analysis model, survival rate of early recurrence in the amiodarone group was higher than in the propafenone group (HR 2.30, 95%CI 1.17–4.53, p = 0.016) and in the sotalol group (HR 3.60, 95%CI 2.17–5.95, p < 0.001). Compared to the amiodarone group, the incidence of liver dysfunction was lower in the dronedarone group (p = 0.046) and the propafenone group (p = 0.021). The incidence of bradyarrhythmia (p = 0.003), QT interval prolongation (p = 0.035) and atrioventricular transmission block (p = 0.021) were higher in the sotalol group than in the amiodarone group.ConclusionRHI was identified as an independent risk factor for early recurrence among elderly AF patients after RFCA. Compared to amiodarone, propafenone and sotalol exhibited an elevated risk of early recurrence. Although there was no significant difference in early recurrence between amiodarone and dronedarone, dronedarone emerged as the preferred option due to its lower frequency of adverse drug reactions than amiodarone.

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Do oral class I and III antiarrhythmic drugs help maintain sinus rhythm after catheter ablation of atrial fibrillation?

Tort¹,

Sharifan²

2023

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Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm after catheter ablation of atrial fibrillation

Abstract: Oral Class I and III antiarrhythmic drugs for maintaining sinus rhythm a er catheter ablation of atrial fibrillation (Protocol).

Cited by 3 publications

References 69 publications

Concomitant Surgical Ablation for Treatment of Atrial Fibrillation in Patients Undergoing Minimally Invasive Mitral Valve Surgery: A Single-Center Experience in Vietnam

Concomitant Surgical Ablation for Treatment of Atrial Fibrillation in Patients Undergoing Minimally Invasive Mitral Valve Surgery: A Single-Center Experience in Vietnam

Factors influencing early recurrence of atrial fibrillation among elderly patients following radiofrequency catheter ablation and the impact of different antiarrhythmic regimens

Do oral class I and III antiarrhythmic drugs help maintain sinus rhythm after catheter ablation of atrial fibrillation?

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