Oral Candida carriage and resistance against common antifungal agents in hematopoietic stem cell transplantation recipients
Matti Mauramo,
Nurgül Tonoz,
Jörg Halter
et al.
Abstract:Purpose
Allogeneic hematopoietic stem cell transplant (HSCT) recipients receiving long-term and high-dose immunosuppressive medications suffer commonly from oral candida infections. This prospective cohort study examined oral fungal carriage in HSCT recipients and screened the susceptibility against commonly used antifungal agents. An increasing oral occurrence of Candida spp. and the development of resistance against clinically administered fluconazole were hypothesized.
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