Oral appliance therapy in obstructive sleep apnea and snoring - systematic review and new directions of development

Ilea, Aranka; Timuș, Daniela; Höpken, Julian; Andrei, Vlad; Băbțan, Anida-Maria; Petrescu, Nausica Bianca; Câmpian, Radu Septimiu; Boșca, Adina Bianca; Şovrea, Alina Simona; Negucioiu, Marius; Mesaroş, Anca

doi:10.1080/08869634.2019.1673285

Cited by 29 publications

(30 citation statements)

References 42 publications

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“…There are various mandibular advancement appliances used in the treatment of OSAS patients [20]. Among the reasons we prefer the SomnoMed MAS device, which positions the mandible for 8 hours at night for all patients with obstructive sleep apnea syndrome, the sagittal screws placed in the upper part can be activated in the sagittal direction when necessary, the outer part of the apparatus is made of rigid acrylic that wraps all teeth rigidly and increases stabilization,…”

Section: Discussionmentioning

confidence: 99%

Evaluation of facial soft tissues by stereophotogrammetry method in patients with obstructive sleep apnoea: a morphological study

Ünal

Hüseyin

2021

Folia Morphol

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We aimed to use the "SomnoMed MAS" device, which brings the mandible forward in Obstructive Sleep Apnea Syndrome patients due to mandibular retrognathia, and to examine its effects on facial soft tissues by stereophotogrammetry (3dMD) method. Thirty-one patients with a mean age of 44 years and 6 months were included in the study. SomnoMed MAS, one of the splint appliances that position the mandible in front, was applied to all patients and the changes in facial soft tissues were examined by overlapping the images taken at different times with the 3dMD Face system. The obtained data were analyzed statistically and the level of statistical significance was determined as p≤0.05.Mouth width decreased statistically during T0-T1 period. In T0-T2 period, while crista philtri and labiale inferius points moved backwards, Mouth width, nose width decreased and nasal base width increased. In the T0-T3 period, nasal base width increased statistically, the philtrum width and the mouth width decreased, and the soft tissue nasion point came to the fore.Splint treatment, which positions the mandible in front in adult OSAS patients, affected the middle and lower facial soft tissues with the forward and downward translational movement of the lower jaw.

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Section: Discussionmentioning

confidence: 99%

Evaluation of facial soft tissues by stereophotogrammetry method in patients with obstructive sleep apnoea: a morphological study

Ünal

Hüseyin

2021

Folia Morphol

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“…Among various intraoral devices with different action sites, mandibular advancement devices are the most commonly used for treatment of OSA [ 56 ]. 92% of patients with OSA can benefit from OAs for improving the AHI index and symptoms of OSA [ 57 ].…”

Section: Treatment Of Osamentioning

confidence: 99%

Clinical and Research Solutions to Manage Obstructive Sleep Apnea: A Review

Xia

2021

Sensors

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Obstructive sleep apnea (OSA), a common sleep disorder disease, affects millions of people. Without appropriate treatment, this disease can provoke several health-related risks including stroke and sudden death. A variety of treatments have been introduced to relieve OSA. The main present clinical treatments and undertaken research activities to improve the success rate of OSA were covered in this paper. Additionally, guidelines on choosing a suitable treatment based on scientific evidence and objective comparison were provided. This review paper specifically elaborated the clinically offered managements as well as the research activities to better treat OSA. We analyzed the methodology of each diagnostic and treatment method, the success rate, and the economic burden on the world. This review paper provided an evidence-based comparison of each treatment to guide patients and physicians, but there are some limitations that would affect the comparison result. Future research should consider the consistent follow-up period and a sufficient number of samples. With the development of implantable medical devices, hypoglossal nerve stimulation systems will be designed to be smart and miniature and one of the potential upcoming research topics. The transcutaneous electrical stimulation as a non-invasive potential treatment would be further investigated in a clinical setting. Meanwhile, no treatment can cure OSA due to the complicated etiology. To maximize the treatment success of OSA, a multidisciplinary and integrated management would be considered in the future.

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“…ese devices can be mainly distinguished in three categories: mandibular advancement devices, tongue-retaining devices, and soft palate-lifting devices [8,9]. Several systematic reviews on the efficacy of oral appliances (OA) for OSA treatment were published over the past years [9][10][11][12][13][14][15][16]. ese systematic reviews were published from 2006 to 2019 and were based on articles published before 2018 [16].…”

Section: Introductionmentioning

confidence: 99%

“…Several systematic reviews on the efficacy of oral appliances (OA) for OSA treatment were published over the past years [9][10][11][12][13][14][15][16]. ese systematic reviews were published from 2006 to 2019 and were based on articles published before 2018 [16]. Six revisions only include randomised clinical trials (RCT) [9-12, 14, 15], one includes randomised and nonrandomised clinical trials [13], and the other one includes RCT and observational studies [16].…”

Section: Introductionmentioning

confidence: 99%

“…These systematic reviews were published from 2006 to 2019 and were based on articles published before 2018 [ 16 ]. Six revisions only include randomised clinical trials (RCT) [ 9 – 12 , 14 , 15 ], one includes randomised and nonrandomised clinical trials [ 13 ], and the other one includes RCT and observational studies [ 16 ]. All of these systematic reviews include a single RCT without any limitation in the number of sample sizes with a range from a few dozens of patients to less than one hundred patients.…”

Section: Introductionmentioning

confidence: 99%

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Clinical Evidence in the Treatment of Obstructive Sleep Apnoea with Oral Appliances: A Systematic Review

Rossi

Giudice

Pardo

et al. 2021

International Journal of Dentistry

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Background. Recent clinical guidelines have extended indications for oral appliances to subjects affected by moderate-to-severe obstructive sleep apnoea (OSA). The aim of this systematic review covering this important issue for public health is twofold: updating and summarizing the best available scientific evidence by selecting RCTs of quality only, and identifying the therapeutic pathways that can be transferred to the current clinical practice. Methods. All the abstracts which were published before February 18, 2019, have been identified in three electronic databases (PubMed, Web of Science, and Cochrane). The Cochrane Collaboration’s tool for assessing risk of bias was used as an assessment tool in order to evaluate the quality of the selected studies. Results. The search strategy yielded 2,260 studies. After removing duplicates and studies that did not comply with the inclusion criteria, 32 full-text articles were assessed for eligibility, and 17 RCTs were finally included in the qualitative synthesis. The 17 selected studies were very heterogeneous in the type of included RCTs in terms of patient inclusion criteria, sample size, distribution of the two genders in the various groups, duration of treatment, and definition of primary and secondary outcomes, without any restriction on the definition of the control group. A common finding was the positive responsiveness of oral appliance treatment in subjects affected by mild-to-moderate OSA with some evidence for cases of severe OSA. Conclusion. Higher-quality studies are needed in order to provide additional useful guidelines for dental clinicians for OSA management.

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Oral appliance therapy in obstructive sleep apnea and snoring - systematic review and new directions of development

Cited by 29 publications

References 42 publications

Evaluation of facial soft tissues by stereophotogrammetry method in patients with obstructive sleep apnoea: a morphological study

Evaluation of facial soft tissues by stereophotogrammetry method in patients with obstructive sleep apnoea: a morphological study

Clinical and Research Solutions to Manage Obstructive Sleep Apnea: A Review

Clinical Evidence in the Treatment of Obstructive Sleep Apnoea with Oral Appliances: A Systematic Review

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