Oral and Psychological Alterations in Haemophiliac Patients

Abstract

Haemophiliacs are hereditary coagulopathies whose basic anomaly consists of the quantitative or qualitative alteration of one or more plasma proteins in the coagulation system. The objective of this review is to analyse all risk factors, predispositions and alterations to the oral-maxillofacial district in patients with haemophilia. The broader assessment also includes the psychological aspects that could affect the treatment and maintenance of oral conditions. The study takes into consideration all the works in the literature in the last 10 years. Works that present oral, dental and psychological changes in haemophilia patients have been combined. A total of 16 studies were analysed carefully evaluating and explaining all the alterations and risk factors that this disease provides. The aim of the review is to report all the anomalies reported in the literature for these patients, and to direct and update the clinician in the treatment of haemophilia patients.

Oral Health and Molecular Aspects of Malignant Fibrous Histiocytoma Patients: A Systematic Review of the Literature

“…Only one study reported a relapse of the disease 2 weeks after a first surgery consisting of local excision with maxillectomy [38], while 4 studies made no reference to recurrence [32][33][34]40]. These invasive surgeries often require post-surgical rehabilitations [51,52], and in some cases are made complex by the presence of local contraindications (noble anatomical structures [53][54][55][56], or systemic contraindications (general health conditions of the patient [22][23][24]26,57]). Post-surgical and infection management are important [27,28,30].…”

“…Distant metastases of MFH commonly occur via hematogenous or lymphatic spread [1,6,20,21]. Unfortunately, it is not always possible to intervene in a timely manner in these cases, due to delays related to diagnosis or systemic conditions of the patient who need adequate protocols or therapies [22][23][24]. Many syndromic patients or those suffering from systemic diseases may also present intra and post-operative complications [23,25,26] or represent a high post-surgical infection risk [27][28][29] and therefore need adequate therapies [27,30].…”

Oral Health and Fibromyalgia Syndrome: A Systemic Review

“…Medications used for fibromyalgia that may be beneficial for masticatory muscle pain according to De Rossi et al [22]. There are several syndromes and diseases which, due to their characteristics, can be similar to fibromyalgia as symptoms, and which will be excluded, even though they may be concomitant; among them, there are mainly: Sjögren syndrome, due to the low nuclear antibodies contained, multiple sclerosis, other systemic neurological syndromes, arthritis and arthrosis [37,39,[58][59][60][61][62][63]. Due to the impossibility of formulating a diagnosis based on medical evidence, and especially considering the equivocal nature of fibromyalgia, there is no universally adopted therapy whose efficacy is scientifically proven, different drugs are used [59], such as non-steroidal anti-inflammatory drugs (NSAIDs), selective serotonin reuptake inhibitors (SSRIs), cannabinoids, and muscle relaxants.…”

Water Contamination Risks at the Dental Clinic

“…It must be borne in mind that through the instruments of the dental practice, viruses and bacteria present in the water supply are sprayed into the environment in the form of aerosols and come into direct contact with the wounds of the patient undergoing treatment. Furthermore, some patients of the dental practice are more susceptible to this route of infection given their hygienic and dental conditions [27][28][29][30][31][32][33][34][35][36].…”