Oral and dermal toxicity of alkenones extracted from i Isochrysis species i

Abstract

Introduction 3. Materials and methods 3.1. Test materials 3.2. Experimental animals 3.3. Study design 3.4. Suspension 3.5. Sub-acute oral gavage of the alkenones 3.6. Blood analysis 3.7. Histology 3.8. Assessment of the dermal toxicity after the sub-acute administration of alkenones 3.9. Assessment of the toxicity after the sub-chronic dermal administration of alkenones 3.10. Determination of skin water loss 3.11. Statistical analysis 4. Results 4.1. The effects of the sub-acute oral administration from alkenones 4.2. The effects of the sub-acute dermal exposure from alkenones 4.3. The effects of repeated dermal exposure from alkenones 5. Discussion 6. Acknowledgments 7. References