Oral administration of yeast, Saccharomyces cerevisiae, enhances the cellular innate immune response of gilthead seabream (Sparus aurata L.)

Ortuño, Jesús; Cuesta, Alberto; Rodrı́guez, Alejandro; Meseguer, José

doi:10.1016/s0165-2427(01)00406-8

Cited by 243 publications

(168 citation statements)

References 29 publications

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“…That reaction can be related to β-glucans, nucleic acids as well as mannan oligosaccharides [93]. Brewer's yeast may serve as an excellent health promoter for fish culture as even when administered for relatively long periods is able to enhance immune responses as well as growth of various fish species, without causing immunosuppression [94,95]. Furthermore, the relative high levels of nucleic acid nitrogen present (mostly in the form of RNA) that in humans and most monogastric animals can became toxic if taken in excess, as the capacity of excretion of the uric acid formed is limited [96], in fish does not happen due to their very active liver uricase [97].…”

Section: Yeast Treats For Animalsmentioning

confidence: 99%

Yeast: World’s Finest Chef

Faria-Oliveira¹,

Puga²,

Ferreira³

2013

Food Industry

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Section: Yeast Treats For Animalsmentioning

confidence: 99%

Yeast: World’s Finest Chef

Faria-Oliveira¹,

Puga²,

Ferreira³

2013

Food Industry

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“…Neste estudo, não foi observada mortalidade de peixes em nenhum dos tratamentos, provavelmente em razão da permanência de condições laboratoriais adequadas ao desenvolvimento da tilápia do Nilo e dos componentes presentes na levedura e seus derivados (nucleotídeos, oligossacarídeos e complexos de proteínas com polissacarídeos), os quais estão relacionados a benefícios ao sistema imune, conferindo maior resistência frente a infecções bacterianas (SAKAI et al, 2001;ORTUÑO et al, 2002;LI & GATLIN, 2004).…”

Section: ---------------------------------Tratamentos----------------unclassified

“…Na alimentação de peixes, esse ingrediente e seus derivados apresentaram resultados positivos como substitutos da farinha de peixe (PÁDUA, 1996;OLIVA-TELES & GONÇALVES, 2001), de fontes de vitaminas hidrossolúveis (BACCARIN & PEZZATO, 2001), de alimentos funcionais (GAIOTTO, 2005;WATANABE, 2006, PEZZATO, 2006 (HISANO et al, 2007b) e de imunoestimulantes (ORTUÑO et al, 2002;LI E GATLIN, 2003).…”

Section: Introductionunclassified

Utilização de levedura íntegra e seus derivados em dietas para juvenis de tilápia do Nilo

2010

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“…Using whole yeast as the immunostimulant at doses of 1, 5 y 10 g/Kg of feed for 4 weeks, the main effects 513 observed were associated with the highest doses highlighting increased respiratory burst activity, 514 phagocytic ability, natural cytotoxic activity and MPO content in the head kidney of seabream leukocytes 515 [184]. Increases in serum IgM content after 2 week of treatment was also reported [185].…”

mentioning

confidence: 92%

“…In this order several studies using different PAMPs as immunostimulants have been 508 reported. The most frequently studied have been diet additives derived from yeast cultures; by adding the 509 whole yeast [183][184][185][186], the yeast cell walls [187] and also extracts such as MOS [188], chitin [185,189],…”

mentioning

confidence: 99%

The response of fish to immunostimulant diets

Vallejos‐Vidal

Reyes-López

Teles

et al. 2016

Fish & Shellfish Immunology

264

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8 Fish Immunostimulation through dietary manipulation 9The aquaculture sector has shown a rapid growth over the last 30 years with an associated increase in 10 disease problems as result of rapid expansion and amongst other factors high stocking densities. In order 11to maintain fish health and to improve performance immunostimulants have been used as dietary 12 additives to improve weight gain, feed efficiency, and/or disease resistance in cultured fish. 13An immunostimulant is a natural or chemical substance that stimulates the immune system by specific 14(vaccines or antigens) or non-specific (irrespective of antigenic specificity) routes. In Aquaculture, non- 21The immunostimulant effect of dietary supplements in fish has been focused mainly on the evaluation of 22 non-specific immune parameters and, therefore, on the consequences of these treatments on the innate 23 immune system. The innate immune system has both cellular and humoral components by which it carries 24 out its protective function. The major components of the innate immune system at cellular level are 25 leukocytes, mainly monocytes, macrophages and granulocytes [1,2]. Among the granulocytes, neutrophils 26are the most abundant cell-type and their presence has been described in Salmoniformes, Cypriniformes 27 and Perciformes [3]. Neutrophils and macrophages are responsible for the production of bioactive 28 molecules for pathogen recognition and destruction, cellular communication and activation, initiation of 29 an adaptive immune response and later, resolution of an inflammatory response and tissue repair. 30Furthermore, these cell types are responsible in the majority for phagocytosis [4], one of the main 31 mediators of innate immunity to remove pathogens such as bacteria, viruses, and parasites. For this 32 reason, these immune cell types are also called phagocytes. This microbe/killing mechanism triggers 33 diverse antimicrobial processes that use a wide variety of mechanisms including cellular activation, 34 production of oxidative radicals, and the production of cytokines driving the inflammatory response 35 amongst others. 36Two of the most important antimicrobial systems of phagocytic cells are the NADPH phagocyte oxidase 37 and inducible nitric oxide synthase (iNOS) pathways, which are responsible for the generation of 38 superoxide (O2 − ) and nitric oxide (NO) radicals, respectively. NADPH oxidase, a multi-subunit complex, 39 catalyses a one-electron reduction of molecular oxygen into superoxide anion (O2 − ), also referred to as 40 reactive oxygen species (ROS), which is either spontaneously converted to H2O2 or enzymatically by 41 superoxide dismutase (SOD). In comparison to neutrophils, the size of the respiratory burst is much 42 reduced in macrophages [5]. Since O2 − is the first product to be released from the respiratory burst, the 43 measurement of O2 − has been accepted as a direct and accurate way of measuring respiratory burst 44 activity [6]: the reduction of ferricytochrome c to determine extracellular O2 − , and th...

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Oral administration of yeast, Saccharomyces cerevisiae, enhances the cellular innate immune response of gilthead seabream (Sparus aurata L.)

Cited by 243 publications

References 29 publications

Yeast: World’s Finest Chef

Yeast: World’s Finest Chef

Utilização de levedura íntegra e seus derivados em dietas para juvenis de tilápia do Nilo

The response of fish to immunostimulant diets

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