Oral Acitretin and Topical Imiquimod as Neoadjuvant Treatment for Giant Basal Cell Carcinoma

Sanmartín, Verónica; Aguayo, Rafael; Baradad, M.; Casanova, J. M.

doi:10.1016/j.adengl.2012.03.002

Cited by 4 publications

(1 citation statement)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Представленное клиническое наблюдение свидетельствует о недостаточной информированности и онкологической настороженности как пациентов, так и врачей различных специальностей, чем и обусловлена поздняя диагностика уже запущенной стадии заболевания и необходимость конструктивного радикального лечения. С учетом повышенного риска метастазирования и смерти от гигантской БКК актуальными являются ранняя диагностика и своевременное адекватное лечение [7,8,13,[19][20][21][22][23]. Таким образом, гигантская БКК является редкой деструктивной опухолью, требующей своевременной диагностики и адекватной эффективной терапии в каждом конкретном случае.…”

Section: заключениеunclassified

Giant basal cell carcinoma (case report)

Grekova,

Zilberberg,

Rimar

2023

Russian Medical Inquiry

View full text Add to dashboard Cite

Basal cell skin cancer, or basal cell carcinoma (BCC), is the most common malignant tumor originating from skin keratinocytes or hair follicles. Giant BCCs are malignant skin neoplasms sized more than 5 cm with a greater tendency to invasion and metastasis than "standard" BCCs (sized less than 5 cm). Two or more foci in one person at the same time rarely occur. This paper describes a 69-year-old woman with skin lesions affecting the left scapula sized 20×10 cm and xiphoid process sized 7×4.5 cm that have existed for more than 15 years. During this period, the patient received various treatments with temporary insignificant improvement. Dermoscopy of the skin lesion of the scapula revealed pathological tree- like and tortuous vessels, homogeneous white and red zones, and ulcerations. Dermoscopy of skin lesion of the xiphoid process was uninformative because of rough surface hemorrhagic crusts. Cytology identified complexes of basaloid cells with atypia. Pathomorphologically, both tumors belonged to nodular BCC. For additional examination and treatment decisions, the patient was referred to the regional oncological dispensary. KEYWORDS: skin cancer, giant basal cell carcinoma, dermoscopy, pathomorphological examination, nodular type. FOR CITATION: Grekova Yu.N., Zilberberg N.V., Rimar O.G. Giant basal cell carcinoma (case report). Russian Medical Inquiry. 2023;7(6):383– 386 (in Russ.). DOI: 10.32364/2587-6821-2023-7-6-7.

show abstract

Section: заключениеunclassified

Giant basal cell carcinoma (case report)

Grekova,

Zilberberg,

Rimar

2023

Russian Medical Inquiry

View full text Add to dashboard Cite

show abstract

Treatment of multiple Bowen's disease with squamous cell and basal cell carcinomas with oral acitretin combined with excision

Li¹,

Song²,

Zhang³

et al. 2014

Dermatologica Sinica

View full text Add to dashboard Cite

Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options

et al. 2016

View full text Add to dashboard Cite

Giant basal cell carcinomas (GBCCs) are large basal cell carcinomas (BCCs; <5 cm) with a greater propensity to invade and metastasize than standard BCCs. The presence of 2 GBCCs in a single individual is rare. We present the case of a 71-year-old Caucasian male with bilateral GBCCs on the dorsal forearms, measuring 130 cm² and 24 cm², respectively, that developed over a 21-year period. Over this period, the patient treated the tumors with herbal remedies. Histologic evaluation showed a conventional nodular BCC for both tumors. Computed tomography and magnetic resonance imaging revealed a T4N0M0 stage for the larger lesion. Surgical excision and grafting and reconstruction were offered, but he declined. This case highlights a shared belief in holistic treatments and rejection of Western medical interventions that are common among many patients with GBCC. Studies reporting nonsurgical treatments for GBCCs, including radiotherapy, vismodegib, topical imiquimod, and acitretin are reviewed.

show abstract

Oral Acitretin and Topical Imiquimod as Neoadjuvant Treatment for Giant Basal Cell Carcinoma

Cited by 4 publications

References 15 publications

Giant basal cell carcinoma (case report)

Giant basal cell carcinoma (case report)

Treatment of multiple Bowen's disease with squamous cell and basal cell carcinomas with oral acitretin combined with excision

Giant Basal Cell Carcinomas Arising on the Bilateral Forearms of a Patient: A Case Report and Review of Nonsurgical Treatment Options

Contact Info

Product

Resources

About