Abstract:Protein folding and docking framework is crucial for computational structural biology. It can deliver a corresponding 3D structure using given constrains (e.g. distance and orientation distribution constraints proposed by trRosetta). In this paper, we propose OPUS-Fold3, a gradient-based all-atom folding and docking framework. OPUS-Fold3 is capable of modeling protein backbone and side chains either separately or simultaneously using given constrains. As a docking framework, OPUS-Fold3 is also capable of deali… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.