Optogenetic stimulation of the basolateral amygdala-medial entorhinal cortex pathway after spatial training has sex-specific effects on downstream activity-regulated cytoskeletal-associated protein expression
Abstract:Previous work from our laboratory suggests that projections from the basolateral amygdala (BLA) to the medial entorhinal cortex (mEC) are a critical pathway by which the BLA modulates the consolidation of spatial learning. Posttraining optogenetic stimulation of this pathway enhances retention of spatial memories. Evidence also indicates that intra-BLA administration of memory-enhancing drugs increases protein levels of activity-regulated cytoskeletal-associated protein (ARC) in the dorsal hippocampus (DH) and… Show more
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