Optimum viscosity of barium suspension for use in the double contrast barium meal

Dc, Cumberland

doi:10.1007/bf02256492

Cited by 11 publications

(3 citation statements)

References 4 publications

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“…In this study, we use a medical suspension of micrometre‐sized barium sulphate (Micropaque®, Guerbet) to enhance the absorption of the water‐phase. Such medical suspensions are conceived to have specific physical properties (Cumberland, 1977; Plouraboué et al , 2004), that is, a high density to provide highly contrasted radiographs, low viscosity to readily penetrate within small sized areas and extremely reduced settling and flocculation of the particles to provide homogeneous absorption of the X‐rays. Although barium is usually highly toxic, it is commonly safely used as a medical radiocontrast agent for X‐ray imaging of the gastrointestinal tract or angiography because of its insolubility in water.…”

Section: Methodsmentioning

confidence: 99%

Imaging biofilm in porous media using X-ray computed microtomography

Davit

Iltis

Debenest

et al. 2010

Journal of Microscopy

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SummaryIn this study, a new technique for three-dimensional imaging of biofilm within porous media using X-ray computed microtomography is presented. Due to the similarity in X-ray absorption coefficients for the porous media (plastic), biofilm and aqueous phase, an X-ray contrast agent is required to image biofilm within the experimental matrix using X-ray computed tomography. The presented technique utilizes a medical suspension of barium sulphate to differentiate between the aqueous phase and the biofilm. Potassium iodide is added to the suspension to aid in delineation between the biofilm and the experimental porous medium. The iodide readily diffuses into the biofilm while the barium sulphate suspension remains in the aqueous phase. This allows for effective differentiation of the three phases within the experimental systems utilized in this study. The behaviour of the two contrast agents, in particular of the barium sulphate, is addressed by comparing two-dimensional images of biofilm within a pore network obtained by (1) optical visualization and (2) X-ray absorption radiography. We show that the contrast mixture provides contrast between the biofilm, the aqueousphase and the solid-phase (beads). The imaging method is then applied to two three-dimensional packed-bead columns within which biofilm was grown. Examples of reconstructed images are provided to illustrate the effectiveness of the method. Limitations and applications of the technique are discussed. A key benefit, associated with the presented method, is that it captures a substantial amount of information For example, the quantification of changes in porous media effective parameters, such as dispersion or permeability, induced by biofilm growth, is possible using specific upscaling techniques and numerical analysis. We emphasize that the results presented here serve as a first test of this novel approach; issues with accurate segmentation of the images, optimal concentrations of contrast agents and the potential need for use of synchrotron radiation sources need to be addressed before the method can be used for precise quantitative analysis of biofilm geometry in porous media.

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Section: Methodsmentioning

confidence: 99%

Imaging biofilm in porous media using X-ray computed microtomography

Davit

Iltis

Debenest

et al. 2010

Journal of Microscopy

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“…Improved tolerability of ionic iodinated agents can be easily achieved by mixing contrast solutions with flavored drinks [39]. Tolerability of barium-based contrast may be inversely related to its viscosity [40]. Both the ingestion of nine barium tablets over 2 days and a single 250-mL dose of dilute barium have been well tolerated [11••].…”

Section: Tagging Techniquesmentioning

confidence: 99%

Decreased-Purgation CT Colonography: State of the Art

Mahgerefteh

Blachar

Fraifeld

2011

Curr Colorectal Cancer Rep

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In the setting of CT colonography (CTC), decreasing bowel preparation measures may help to optimize colorectal cancer screening compliance without compromising accuracy. Decreased-purgation or wholly noncathartic CTC, known as nonconventional CTC, may be accomplished in conjunction with fecal tagging. Image post-processing technologies such as electronic cleansing and computer-aided detection may boost accuracy and decrease the need for bowel preparation even further. We review pre-study preparation and image post-processing techniques that have been described in nonconventionalpreparation CTC studies over the past 10 years. We explore in detail specific aspects of nonconventional cathartic and fecal tagging regimens, including substance, dose, and time frame of ingestion.

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“…It has great potential in organ tracking, especially for deep-tissue diagnosis [ 116 ]. X-ray radiography is a common method for gastrointestinal disease diagnosis [ 117 , 118 , 119 ]. Before the X-ray radiography, the patient needs to take the contrast agent orally, such as in the form of a barium meal.…”

Section: In Vivo Trackingmentioning

confidence: 99%

Organic Semiconducting Nanoparticles for Biosensor: A Review

et al. 2023

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Highly bio-compatible organic semiconductors are widely used as biosensors, but their long-term stability can be compromised due to photo-degradation and structural instability. To address this issue, scientists have developed organic semiconductor nanoparticles (OSNs) by incorporating organic semiconductors into a stable framework or self-assembled structure. OSNs have shown excellent performance and can be used as high-resolution biosensors in modern medical and biological research. They have been used for a wide range of applications, such as detecting small biological molecules, nucleic acids, and enzyme levels, as well as vascular imaging, tumor localization, and more. In particular, OSNs can simulate fine particulate matters (PM2.5, indicating particulate matter with an aerodynamic diameter less than or equal to 2.5 μm) and can be used to study the biodistribution, clearance pathways, and health effects of such particles. However, there are still some problems that need to be solved, such as toxicity, metabolic mechanism, and fluorescence intensity. In this review, based on the structure and design strategies of OSNs, we introduce various types of OSNs-based biosensors with functional groups used as biosensors and discuss their applications in both in vitro and in vivo tracking. Finally, we also discuss the design strategies and potential future trends of OSNs-based biosensors. This review provides a theoretical scaffold for the design of high-performance OSNs-based biosensors and highlights important trends and future directions for their development and application.

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Optimum viscosity of barium suspension for use in the double contrast barium meal

Cited by 11 publications

References 4 publications

Imaging biofilm in porous media using X-ray computed microtomography

Imaging biofilm in porous media using X-ray computed microtomography

Decreased-Purgation CT Colonography: State of the Art

Organic Semiconducting Nanoparticles for Biosensor: A Review

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