1999
DOI: 10.1111/j.0006-341x.1999.00437.x
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Optimum Experimental Designs for Multinomial Logistic Models

Abstract: Multinomial responses frequently occur in dose level experiments. For example, in a study of the influence of gamma radiation on the emergence of house flies (Musca domestica L., 1758), three disjoint outcomes occurred: death before the pupae opened, death during emergence, and life after emergence. Although the flies are easy to breed, this sort of bioassay is, in general, very expensive since it requires the use of a gamma radiation source. Experiments therefore need to be designed to involve the minimum num… Show more

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Cited by 43 publications
(27 citation statements)
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References 34 publications
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“…Inequality (21) implies that lim t→∞ Φ p Σ ξ 0 +ξ S (t) (g) = −∞, which contradicts the fact that Φ p Σ ξ 0 +ξ S (t) (g) is a nonnegative function. Similar arguments can be applied to the case when K ≤ δ, in which we let α = 1.…”
Section: Appendixmentioning
confidence: 95%
See 1 more Smart Citation
“…Inequality (21) implies that lim t→∞ Φ p Σ ξ 0 +ξ S (t) (g) = −∞, which contradicts the fact that Φ p Σ ξ 0 +ξ S (t) (g) is a nonnegative function. Similar arguments can be applied to the case when K ≤ δ, in which we let α = 1.…”
Section: Appendixmentioning
confidence: 95%
“…Optimal designs for model (10) depend on the values of the unknown parameters (Zocchi and Atkinson, 1999). We assume that θ 1 = (1, 1, −1, 2) and θ 2 = (−1, 2, 1, −1), and let the design space X = {(6i/s, 6j/s, 6k/s), i, j, l = 0, 1, .…”
Section: Examplementioning
confidence: 99%
“…Chaloner and Larntz (1989) considered determination of optimal design for experiments using logistic regression. Zocchi and Atkinson (1999) considered design for multinomial logistic models. Dey, Ghosh, and Mallick (2000) edited a collection of articles that provided Bayesian analyses for GLMs.…”
Section: Binary Regressionmentioning
confidence: 99%
“…For multinomial data, the response may be modelled using a multivariate GLM [35], with potentially different linear predictors used to describe the probability of success in each category, together with an identifiability constraint. The design problem is then a natural generalisation of that given in Section 2, using a suitably defined information matrix [36] which will depend on the parameters from each linear predictor.…”
Section: Discussionmentioning
confidence: 99%