Optimizing respiratory management in preterm infants: a review of adjuvant pharmacotherapies

Koo, Jenny; Steinhorn, Robin H.; Katheria, Anup

doi:10.1038/s41372-021-01139-x

Cited by 2 publications

(3 citation statements)

References 109 publications

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“…Various papers have suggested fundamental characteristics that need to be considered when implementing ICR/S during a Csection. 10,34,35 It is important to have a stable, flat and soft, but firm surface where the neonate can be safely placed during resuscitation. 34 The surface must fulfil the requirements for aseptic conditions in the operating theatre.…”

Section: Discussionmentioning

confidence: 99%

“…9 It has been hypothesised that delayed cord clamping is even more important for neonates who require resuscitative efforts after birth than for vigorous neonates. 10 Feasibility studies of intact cord resuscitation and/or stabilisation (ICR/S) of preterm and term neonates have shown promising results. There are ongoing clinical trials that are exploring strategies for optimising cardiopulmonary resuscitation during delayed cord clamping.…”

Section: Backg Rou N Dmentioning

confidence: 99%

“…On a global level, up to 10% of neonates require interventions to facilitate their transition after birth, while 1% need more extensive resuscitation to stabilise them 9 . It has been hypothesised that delayed cord clamping is even more important for neonates who require resuscitative efforts after birth than for vigorous neonates 10 . Feasibility studies of intact cord resuscitation and/or stabilisation (ICR/S) of preterm and term neonates have shown promising results.…”

Section: Introductionmentioning

confidence: 99%

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Stabilisation and resuscitation with intact cord circulation is feasible using a wide variety of approaches; a scoping review

Alikhani,

Thies‐Lagergren,

Svedenkrans

et al. 2023

Acta Paediatrica

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AimThis scoping review identified studies on approaches to intact cord resuscitation and/or stabilisation (ICR/S) for neonates delivered by Caesarean section (C‐section).MethodsA systematic literature search was carried out using the PubMed, Web of Science, Scopus, Cochrane and CINAHL databases to identify papers published in English from inception to 14 November 2022.ResultsWe assessed 2613 studies and included 18 from 10 countries, covering 1–125 C‐sections: the United States, the United Kingdom, Australia, India, Italy, China, France, The Netherlands, New Zealand and Taiwan. The papers were published from 2014 to 2023, and the majority were randomised controlled trials and observational studies. Different platforms, equipment and staff positions in relation to the operating table were described. Options for resuscitation and stabilisation included different bedding and trolley approaches, and maintaining aseptic conditions was mainly addressed by the neonatal team scrubbing in. Hypothermia was prevented by using warm surfaces, polythene bags and radiant heaters. Equipment was kept easily accessible by mounting it on a trolley or a separate mobile pole.ConclusionWe could not reach definitive conclusions on the optimal method for performing ICR/S during a C‐section, due to study variations. However, a number of equipment and management options appeared to be feasible approaches.

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