Optimizing elderly pharmacotherapy: polypharmacy vs. undertreatment. Are these two concepts related?

Blanco-Reina, Encarnación; Ariza-Zafra, Gabriel; Ocaña-Riola, Ricardo; León-Ortíz, Matilde; Bellido, I.

doi:10.1007/s00228-014-1780-0

Cited by 51 publications

(65 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The criteria, along with other available explicit criteria, is also criticized by the conflicting evidence of whether their application can achieve objective and measurable improvements in clinical outcomes and prevent possible drug-related adverse events [20,22,[42][43][44][45][46].…”

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Prevalence and predictors of potentially inappropriate medications among home care elderly patients in Qatar

2015

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 98%

“…A more recent study conducted in Spain revealed that the 2012 Beers criteria detected the highest number of PIMs (44 %) when compared to the 2003 Beers and the 2008 STOPP-START criteria (24.3 and 35.4 %, respectively) [22].…”

mentioning

confidence: 98%

Prevalence and predictors of potentially inappropriate medications among home care elderly patients in Qatar

2015

View full text Add to dashboard Cite

show abstract

“…An association has been demonstrated between polypharmacy (using ≥ five medications concomitantly) and underprescribing [27], so the high rate of concurrent PIMs and PPOs is not unexpected.…”

Section: Discussionmentioning

confidence: 99%

Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people

Moriarty

Bennett

Fahey

et al. 2015

Eur J Clin Pharmacol

View full text Add to dashboard Cite

PurposeThis study aims to compare the prevalence of potentially inappropriate medicines (PIMs) and potential prescribing omissions (PPOs) using several screening tools in an Irish community-dwelling older cohort, to assess if the prevalence changes over time and to determine factors associated with any change.MethodsThis is a prospective cohort study of participants aged ≥65 years in The Irish Longitudinal Study on Ageing (TILDA) with linked pharmacy claims data (n = 2051). PIM and PPO prevalence was measured in the year preceding participants’ TILDA baseline interviews and in the year preceding their follow-up interviews using the Screening Tool for Older Persons’ Prescriptions (STOPP), Beers criteria (2012), Assessing Care of Vulnerable Elders (ACOVE) indicators and the Screening Tool to Alert doctors to Right Treatment (START). Generalised estimating equations were used to determine factors associated with change in prevalence over time.ResultsDepending on the screening tool used, between 19.8 % (ACOVE indicators) and 52.7 % (STOPP) of participants received a PIM at baseline, and PPO prevalence ranged from 38.2 % (START) to 44.8 % (ACOVE indicators), while 36.7 % of participants had both a PIM and PPO. Common criteria were aspirin for primary prevention (19.6 %) and omission of calcium/vitamin D in osteoporosis (14.7 %). Prevalence of PIMs and PPOs increased at follow-up (PIMs range 22–56.1 %, PPOs range 40.5–49.3 %), and this was associated with patient age, female sex, and numbers of medicines and chronic conditions.ConclusionsSub-optimal prescribing is common in older patients. Ongoing prescribing review to optimise care is important, particularly as patients get older, receive more medicines or develop more illnesses.Electronic supplementary materialThe online version of this article (doi:10.1007/s00228-015-1815-1) contains supplementary material, which is available to authorized users.

show abstract

“…Compliance with recommendations based on START.v1 criteria, while highly variable, is overall low [12]. When the exact reasons for this variability are still unclear, in some instances, the reasons may be low or conflicting with scientific evidence in old complex patients [13][14][15], controversy of preventive medicine in such population [16], or the fear of polypharmacy [17].…”

Section: Introductionmentioning

confidence: 99%

Application of STOPP/START and Beers criteria: Compared analysis on identification and relevance of potentially inappropriate prescriptions

Boland

Guignard

Dalleur

et al. 2016

European Geriatric Medicine

View full text Add to dashboard Cite

Optimizing elderly pharmacotherapy: polypharmacy vs. undertreatment. Are these two concepts related?

Abstract: Our findings show high rates of polypharmacy and PPO, as well as a clear relationship between these two concepts.

Cited by 51 publications

References 58 publications

Prevalence and predictors of potentially inappropriate medications among home care elderly patients in Qatar

Prevalence and predictors of potentially inappropriate medications among home care elderly patients in Qatar

Longitudinal prevalence of potentially inappropriate medicines and potential prescribing omissions in a cohort of community-dwelling older people

Application of STOPP/START and Beers criteria: Compared analysis on identification and relevance of potentially inappropriate prescriptions

Contact Info

Product

Resources

About