Optimizing early neurological deterioration prediction in acute ischemic stroke patients following intravenous thrombolysis: a LASSO regression model approach
Ning Li,
Ying-Lei Li,
Jia-Min Shao
et al.
Abstract:BackgroundAcute ischemic stroke (AIS) remains a leading cause of disability and mortality globally among adults. Despite Intravenous Thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) emerging as the standard treatment for AIS, approximately 6–40% of patients undergoing IVT experience Early Neurological Deterioration (END), significantly impacting treatment efficacy and patient prognosis.ObjectiveThis study aimed to develop and validate a predictive model for END in AIS patients post rt-P… Show more
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