Optimized Reconstruction Algorithm Based Analysis of Effects of Exercise Therapy Combined with Celecoxib Capsules on the Rehabilitation of Knee Osteoarthritis Using Computed Tomography Images

Abstract

The aim was to explore the application value of computed tomography (CT) images based on optimized reconstruction algorithm (ORA) in knee osteoarthritis (KOA) and to analyze the rehabilitation effect of exercise therapy combined with celecoxib capsules on KOA. On the basis of iterative reconstruction algorithm, sparse data and compressed sensing (CS) algorithm were introduced in this study for the image reconstruction and were compared with the reconstruction effects of other algorithms. 105 patients with KOA were selected as the subjects investigated, who were treated in the hospital from December 2018 to January 2020. They were divided randomly into group A (exercise therapy), group B (celecoxib capsule therapy), and group C (exercise therapy combined with celecoxib capsules), with 35 patients in each group. All the patients were scanned by CT. Visual analogue score (VAS) method was adopted to compare the pain symptoms of patients in the three groups before and after treatment. The Lysholm knee function score was employed to evaluate the knee function of the patient before and after treatment, and finally the difference in the total effective rate of treatment was compared. The results showed that the reconstruction algorithm in this study had a higher degree of coincidence with the original image, and its root mean square error (RMSE), peak signal-to-noise ratio (PSNR), and structural similarity (SSIM) were greatly higher than those of filtered back-projection (FBP) algorithm. There was no huge difference between Lysholm score and VAS in patients of the three groups before treatment ( P > 0.05 ). Besides, Lysholm score in all dimensions and its total score after treatment were higher than those of patients in the three groups before treatment ( P < 0.05 ), and those of patients in group C increased extremely in contrast to group A ( P < 0.05 ). VAS after treatment were all lower in patients of the three groups than those before treatment ( P < 0.05 ), and VAS of patients in group C were sharply lower than those of group A ( P < 0.05 ), but the total effective rate of patients in group C was dramatically higher than the rate of group A ( P < 0.05 ). It indicated that an algorithm with short scanning time and good image quality was established based on iterative reconstruction algorithm. Exercise therapy combined with celecoxib capsules could alleviate the pain symptoms and improve the function of knee joint, which was more advantageous than the simple rehabilitation comprehensive therapy. Therefore, it had higher clinical value for the patients with KOA.