Optimization of window settings for virtual monoenergetic imaging in dual-energy CT of the liver: A multi-reader evaluation of standard monoenergetic and advanced imaged-based monoenergetic datasets

Cecco, Carlo N. De; Caruso, Damiano; Schoepf, U. Joseph; Wichmann, Julian L.; Louw, Janet R. Ter; Perry, Jonathan; Picard, Melissa M.; Schaefer, Amanda R.; Parker, Leland W.; Hardie, Andrew D.

doi:10.1016/j.ejrad.2016.01.007

Cited by 47 publications

(22 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…De Cecco et al [7] determined that parenchymal and vascular attenuation could be significantly increased using the Mono + algorithm at 50 keV when compared to 70 keV using a standard mono-energetic algorithm and blended images. This study also showed that lesion detectability was optimized using this low 50 keV setting.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

et al. 2017

View full text Add to dashboard Cite

Purpose Single-energy low tube potential (SE-LTP) and dual-energy virtual monoenergetic (DE-VM) CT images both increase the conspicuity of hepatic lesions by increasing iodine signal. Our purpose was to compare the conspicuity of proven liver lesions, artifacts, and radiologist preferences in dose-matched SE-LTP and DE-VM images. Methods Thirty-one patients with 72 proven liver lesions (21 benign, 51 malignant) underwent full-dose contrast-enhanced dual-energy CT (DECT). Half-dose images were obtained using single tube reconstruction of the dual-source SE-LTP projection data (80 or 100 kV), and by inserting noise into dual-energy projection data, with DE-VM images reconstructed from 40 to 70 keV. Three blinded gastrointestinal radiologists evaluated half-dose SE-LTP and DE-VM images, ranking and grading liver lesion conspicuity and diagnostic confidence (4-point scale) on a per-lesion basis. Image quality (noise, artifacts, sharpness) was evaluated, and overall image preference was ranked on per-patient basis. Lesion-to-liver contrast-to-noise ratio (CNR) was compared between techniques. Results Mean lesion size was 1.5 ± 1.2 cm. Across the readers, the mean conspicuity ratings for 40, 45, and 50 keV half-dose DE-VM images were superior compared to other half-dose image sets (p < 0.0001). Perlesion diagnostic confidence was similar between halfdose SE-LTP compared to half-dose DE-VM images (p ≥ 0.05; 1.19 vs. 1.24–1.32). However, SE-LTP images had less noise and artifacts and were sharper compared to DE-VM images less than 70 keV (p < 0.05). On a per-patient basis, radiologists preferred SE-LTP images the most and preferred 40–50 keV the least (p < 0.0001). Lesion CNR was also higher in SE-LTP images than DE-VM images (p < 0.01). Conclusion For the same applied dose level, liver lesions were more conspicuous using DE-VM compared to SE-LTP; however, SE-LTP images were preferred more than any single DE-VM energy level, likely due to lower noise and artifacts.

show abstract

Section: Discussionmentioning

confidence: 99%

“…Several studies have investigated the use of DE VM imaging on both anthropomorphic phantoms with simulated abdominal lesions, as well as in patient cohorts [7–11]. …”

mentioning

confidence: 99%

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

et al. 2017

View full text Add to dashboard Cite

show abstract

“…Because blended images were equivalent to conventional CT images, the result justified using 70 keV images as a reference . Furthermore, the optimal W‐L values for 50 keV images were significantly higher and wider and offered notably improved detection sensitivity . This suggested significant potential for optimizing low‐keV image W‐L values.…”

Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

“…De Cecco et al assessed the impact of W‐L values for 50 keV, 70 keV, and linearly blended images . The optimal W‐L values were manually determined by two radiologists for cancer detection tasks . The result showed that the optimal W‐L values for 70 keV images were similar to those for linearly blended images, due to similar lesion and liver attenuation properties .…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Optimizing window settings for improved presentation of virtual monoenergetic images in dual‐energy computed tomography

Marin

Ramírez-Giraldo

et al. 2017

Medical Physics

View full text Add to dashboard Cite

show abstract

Spinal dual-energy computed tomography: improved visualisation of spinal tumorous growth with a noise-optimised advanced monoenergetic post-processing algorithm

et al. 2016

View full text Add to dashboard Cite

show abstract

Optimization of window settings for virtual monoenergetic imaging in dual-energy CT of the liver: A multi-reader evaluation of standard monoenergetic and advanced imaged-based monoenergetic datasets

Cited by 47 publications

References 17 publications

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

Low kV versus dual-energy virtual monoenergetic CT imaging for proven liver lesions: what are the advantages and trade-offs in conspicuity and image quality? A pilot study

Optimizing window settings for improved presentation of virtual monoenergetic images in dual‐energy computed tomography

Spinal dual-energy computed tomography: improved visualisation of spinal tumorous growth with a noise-optimised advanced monoenergetic post-processing algorithm

Contact Info

Product

Resources

About