Optimization of the QuEChERS extraction procedure for the determination of polycyclic aromatic hydrocarbons in soil by gas chromatography-mass spectrometry

Cvetković, Jelena; Mitić, Violeta; Stаnkov-Jovаnović, Vesnа; Dimitrijević, Marija; Petrović, Goran; Nikolić, Jelena S.; Stojanović, Gordana

doi:10.1039/c5ay03248b

Cited by 35 publications

(18 citation statements)

References 27 publications

(23 reference statements)

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“…One of the most significant sources of PAHs for humans is soil, wherefrom they can reach air, water and food (Cvetkovic et al, 2016).…”

Section: Resultsmentioning

confidence: 99%

“…More recently, modified versions of the QuEChERS technique has been reported for the analysis of PAHs in soils using GC-MS chromatography (Cvetkovic et al, 2016). There is a need to take advantage of QuEChERS ability to recover a broad range of chemical compounds that can target both parent compounds and metabolites or transformation products.…”

mentioning

confidence: 99%

“…organic acids, certain polar pigments and sugars) (González-Curbelo et al, 2015). The QuEChERS method has been reported to be very adaptable with different matrices, samples sizes and extraction solvents and provides high analyte recoveries (Baduel et al, 2015;Cvetkovic et al, 2016;DeArmond et al, 2015). With such inherent advantages and its "Green Chemistry characteristics (Guardia and Garrigues, 2012), the QuEChERS approach has rapidly expanded to the extraction of different groups of compounds from environmental to bioanalytical matrices (González-Curbelo et al, 2015).…”

mentioning

confidence: 99%

“…Some of the key analytical methods mainly used in the analysis of PAHs and OH-PAHs in biological matrices include an extraction step such as soxhlet extraction (Cvetkovic et al, 2016), solid phase extraction (Baduel et al, 2015), and accelerated solvent extraction (Li et al, 2003) which is coupled to sample clean-up using a dispersive solid phase extraction (Baduel et al, 2015), gel permeation chromatography (Cloutier et al, 2017) or silica gel (Cvetkovic et al, 2016). However, these techniques are often time consuming and mainly use a large volume of chlorinated solvent for extraction.…”

mentioning

confidence: 99%

“…With such inherent advantages and its "Green Chemistry characteristics (Guardia and Garrigues, 2012), the QuEChERS approach has rapidly expanded to the extraction of different groups of compounds from environmental to bioanalytical matrices (González-Curbelo et al, 2015). In the past 10 years a number of QuEChERS protocols have been developed for the analysis of the US-EPA PAHs in both environmental and biological matrices (Anastassiades et al, 2003;Baduel et al, 2015;Cvetkovic et al, 2016;DeArmond et al, 2015). However, the application of QuEChERS approach for the analysis of OH-PAHs is limited to a study on milk samples (Knobel et al, 2013) and rat brain tissue (Grova et al, 2011).…”

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confidence: 99%

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Health risk assessment of mixed contaminants: Interaction of metals on the uptake of polycyclic aromatic hydrocarbons in human liver cells

Lal¹

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A key area of uncertainty in human health risk assessment of chemical mixtures is the application of additivity of dose or effects, which may overestimate or underestimate the actual risk. In this PhD thesis, interaction effects among mixtures of benzo [a]pyrene (B[a]P), pyrene (Pyr), phenanthrene (Phe) and naphthalene (Nap) in the presence or absence of arsenic (As), cadmium (Cd), lead (Pb) is elucidated for bioaccessibility, uptake (surrogate bioavailability) and metabolism of PAHs in human systems using in vitro models. A simulated human digestion based on the use of an in vitro model (Unified BARGE Method) was used to quantify PAH bioaccessibility from exposure to contaminated soils, whereas a human liver hepatocellular (HepG2) cell line (surrogate liver) was used as an in vitro model to quantify uptake and metabolism of PAHs. This PhD To investigate bioaccessibility of PAHs, seven chemically-variant top soils were collected from background sites in Australia and were spiked with PAHs and aged up to 90 days.The UBM results suggest that the most significant interactions between PAHs and soil components controlling its bioaccessibility was completed by the first 7 days of ageing condition of this study. It is noted that there was a significant lower bioaccessibility of Data from pure solution study suggests that uptake of PAHs and in the presence of As, Cd, and Pb in HepG2 cells generally showed less than additive effects among binary, ternary and seven compound mixtures of B[a]P, Pyr, Phe and Nap. Notably, the % uptake of Phe in HepG2 cells was found to decrease significantly in the seven compound mixture (p < 0.05) which had As, Cd and Pb. Using UBM-extracted solutions, interaction effects on uptake of PAHs in HepG2 cells was found to be both additive and less than additive.Moreover, the % uptake data from UBM-extracted real soil samples showed a decrease in % uptake of B[a]P, Pyr, Phe and Nap by 0.7 %, 1.8 %, 0.4 % and 0.04 %, respectively when compared to their individual PAH % uptake in HepG2 cells from exposure to UBMextracted spiked soil samples.Results of bioaccessibility, uptake and metabolism of B[a]P, Pyr, Phe and Nap as individual compounds or mixtures in the presence or absence of As, Cd and Pb provide significant new understanding towards interaction effects of these compounds in the context of human health risk assessment. For assessment of soils contaminated with PAHs and metal/loids, it clarifies situations where additive effects can be expected rather than assuming additivity as a general rule in risk assessment of chemical mixtures.4

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“…One of the most significant sources of PAHs for humans is soil, wherefrom they can reach air, water and food (Cvetkovic et al, 2016).…”

Section: Resultsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

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Health risk assessment of mixed contaminants: Interaction of metals on the uptake of polycyclic aromatic hydrocarbons in human liver cells

Lal¹

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Characterization of synthetic dyes for environmental and forensic assessments: A chromatography and mass spectrometry approach

Terán

Millbern

Shao

et al. 2020

J of Separation Science

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Dyes have become common substances since they are employed in mostly all objects surrounding our daily activities such as clothing and upholstery. Based on the usage and disposal of these objects, the transfer of the dyes to other media such as soil and water increases their prevalence in our environment. However, this prevalence could help to solve crimes and pollution problems if detection techniques are proper. For that reason, the detection and characterization of dyes in complex matrices is important to determine the possible events leading to their deposition (natural degradation, attempts of removal, possible match with evidence, among others).Currently, there are several chromatographic and mass spectrometric approaches used for the identification of these organic molecules and their derivatives with high specificity and accuracy. This review presents current chromatographic and mass spectrometric methods that are used for the detection and characterization of disperse, acid, basic, and reactive dyes, and their derivatives.

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Development of Optical Sensor Strips for Point-of-Care Testing for Pesticide

Mohanta

Bhatt

Deep

et al. 2020

Environmental Chemistry for a Sustainable World

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Optimization of the QuEChERS extraction procedure for the determination of polycyclic aromatic hydrocarbons in soil by gas chromatography-mass spectrometry

Abstract: This study proposes a QuEChERS variant for the extraction of PAHs in soil followed by GC-MS analysis.

Cited by 35 publications

References 27 publications

Health risk assessment of mixed contaminants: Interaction of metals on the uptake of polycyclic aromatic hydrocarbons in human liver cells

Health risk assessment of mixed contaminants: Interaction of metals on the uptake of polycyclic aromatic hydrocarbons in human liver cells

Characterization of synthetic dyes for environmental and forensic assessments: A chromatography and mass spectrometry approach

Development of Optical Sensor Strips for Point-of-Care Testing for Pesticide

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